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Chimeric antigen receptors: driving immunology towards synthetic biology

Current opinion in immunology, 2016-08, Vol.41, p.68-76

Sadelain, Michel

2016

Volltextzugriff (PDF)

Gene therapy comes of age

Science (American Association for the Advancement of Science), 2018-01, Vol.359 (6372)

2018

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PD-1- and CTLA-4-based inhibitory chimeric antigen receptors (iCARs) divert off-target immunotherapy responses

Science translational medicine, 2013-12, Vol.5 (215), p.215ra172

2013

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Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia

The New England journal of medicine, 2018-02, Vol.378 (5), p.449-459

2018

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The pharmacology of second-generation chimeric antigen receptors

Nature reviews. Drug discovery, 2015-07, Vol.14 (7), p.499-509

2015

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The promise and potential pitfalls of chimeric antigen receptors

Current opinion in immunology, 2009-04, Vol.21 (2), p.215-223

2009

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The Journey from Discoveries in Fundamental Immunology to Cancer Immunotherapy

Cancer cell, 2015-04, Vol.27 (4), p.439-449

2015

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Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Nature biotechnology, 2009-03, Vol.27 (3), p.275-280

2009

Volltextzugriff (PDF)

Clinical Impact of Immune Microenvironment in Stage I Lung Adenocarcinoma: Tumor Interleukin-12 Receptor β2 (IL-12Rβ2), IL-7R, and Stromal FoxP3/CD3 Ratio Are Independent Predictors of Recurrence

Journal of clinical oncology, 2013-02, Vol.31 (4), p.490-498

2013

Volltextzugriff (PDF)

Mesothelin Overexpression Promotes Mesothelioma Cell Invasion and MMP-9 Secretion in an Orthotopic Mouse Model and in Epithelioid Pleural Mesothelioma Patients

Clinical cancer research, 2012-05, Vol.18 (9), p.2478-2489

2012

Volltextzugriff (PDF)

Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (31), p.12759-12764

2009

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Genome Editing Technologies: Defining a Path to Clinic

Molecular therapy, 2015-05, Vol.23 (5), p.796-806

2015

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The Potential of Stem Cells as an In Vitro Source of Red Blood Cells for Transfusion

Cell stem cell, 2012-02, Vol.10 (2), p.115-119

2012

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miR-371-3 Expression Predicts Neural Differentiation Propensity in Human Pluripotent Stem Cells

Cell stem cell, 2011-06, Vol.8 (6), p.695-706

2011

Volltextzugriff (PDF)

Cancer antigen profiling for malignant pleural mesothelioma immunotherapy: expression and coexpression of mesothelin, cancer antigen 125, and Wilms tumor 1

Oncotarget, 2017-09, Vol.8 (44), p.77872-77882

2017

Volltextzugriff (PDF)

Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition

Blood, 2013-01, Vol.121 (5), p.770-780

2013

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Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain

Nature biotechnology, 2005-05, Vol.23 (5), p.601-606

2005

Volltextzugriff (PDF)

A method to sequence and quantify DNA integration for monitoring outcome in gene therapy

Nucleic acids research, 2011-06, Vol.39 (11), p.e72

2011

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Chronic inflammation in tumor stroma is an independent predictor of prolonged survival in epithelioid malignant pleural mesothelioma patients

Cancer Immunology, Immunotherapy, 2011-12, Vol.60 (12), p.1721-1728

2011

Volltextzugriff (PDF)

An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity

Molecular therapy. Oncolytics, 2016, Vol.3 (C), p.1-9, Article 16023

2016

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Prostate-specific membrane antigen retargeted measles virotherapy for the treatment of prostate cancer

The Prostate, 2009-07, Vol.69 (10), p.1128-1141

2009

Volltextzugriff (PDF)

Intercellular Transfer of P-Glycoprotein Mediates Acquired Multidrug Resistance in Tumor Cells

Proceedings of the National Academy of Sciences - PNAS, 2005-02, Vol.102 (6), p.1933-1938

2005

Volltextzugriff (PDF)

A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference

Nature biotechnology, 2006-01, Vol.24 (1), p.89-94

2006

Volltextzugriff (PDF)

Escape Mutations, Ganciclovir Resistance, and Teratoma Formation in Human iPSCs Expressing an HSVtk Suicide Gene

Molecular therapy. Nucleic acids, 2016, Vol.5 (2), p.e284-e284, Article e284

2016

Volltextzugriff (PDF)

Abstract 3499: CD56 targeted chimeric antigen receptors for immunotherapy of multiple myeloma

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.3499-3499

2012

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Chimeric antigen receptors: driving immunology towards synthetic biology

Gene therapy comes of age

PD-1- and CTLA-4-based inhibitory chimeric antigen receptors (iCARs) divert off-target immunotherapy responses

Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia

The pharmacology of second-generation chimeric antigen receptors

The promise and potential pitfalls of chimeric antigen receptors

The Journey from Discoveries in Fundamental Immunology to Cancer Immunotherapy

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Clinical Impact of Immune Microenvironment in Stage I Lung Adenocarcinoma: Tumor Interleukin-12 Receptor β2 (IL-12Rβ2), IL-7R, and Stromal FoxP3/CD3 Ratio Are Independent Predictors of Recurrence

Mesothelin Overexpression Promotes Mesothelioma Cell Invasion and MMP-9 Secretion in an Orthotopic Mouse Model and in Epithelioid Pleural Mesothelioma Patients

Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation

Genome Editing Technologies: Defining a Path to Clinic

The Potential of Stem Cells as an In Vitro Source of Red Blood Cells for Transfusion

miR-371-3 Expression Predicts Neural Differentiation Propensity in Human Pluripotent Stem Cells

Cancer antigen profiling for malignant pleural mesothelioma immunotherapy: expression and coexpression of mesothelin, cancer antigen 125, and Wilms tumor 1

Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition

Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain

A method to sequence and quantify DNA integration for monitoring outcome in gene therapy

Chronic inflammation in tumor stroma is an independent predictor of prolonged survival in epithelioid malignant pleural mesothelioma patients

An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity

Prostate-specific membrane antigen retargeted measles virotherapy for the treatment of prostate cancer

Intercellular Transfer of P-Glycoprotein Mediates Acquired Multidrug Resistance in Tumor Cells

A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA interference

Escape Mutations, Ganciclovir Resistance, and Teratoma Formation in Human iPSCs Expressing an HSVtk Suicide Gene

Abstract 3499: CD56 targeted chimeric antigen receptors for immunotherapy of multiple myeloma

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