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Oxysterols: From physiological tuners to pharmacological opportunities

British journal of pharmacology, 2021-08, Vol.178 (16), p.3089-3103

2021

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Biochemical and molecular mechanisms of action of bisphosphonates

Bone (New York, N.Y.), 2011-07, Vol.49 (1), p.34-41

2011

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Cellular and molecular mechanisms of action of bisphosphonates

Cancer, 2000-06, Vol.88 (12), p.2961-2978

2000

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putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (38), p.16511-16516

2009

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Molecular Mechanisms of Action of Bisphosphonates: Current Status

Clinical cancer research, 2006-10, Vol.12 (20), p.6222s-6230s

2006

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Technological variation in the earliest Oldowan from Gona, Afar, Ethiopia

Journal of human evolution, 2010-06, Vol.58 (6), p.474-491

2010

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Ardipithecus ramidus postcrania from the Gona Project area, Afar Regional State, Ethiopia

Journal of human evolution, 2019-04, Vol.129, p.1-45

2019

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Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer

Cancer discovery, 2015-01, Vol.5 (1), p.35-42

2015

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Estimating sexual size dimorphism in fossil species from posterior probability densities

Proceedings of the National Academy of Sciences - PNAS, 2021-11, Vol.118 (44), p.1

2021

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Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and non-resorbing cells

Bone (New York, N.Y.), 2008-05, Vol.42 (5), p.848-860

2008

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The Molecular Mechanism of Nitrogen-Containing Bisphosphonates as Antiosteoporosis Drugs

Proceedings of the National Academy of Sciences - PNAS, 2006-05, Vol.103 (20), p.7829-7834

2006

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Molecular mechanisms of action of bisphosphonates and new insights into their effects outside the skeleton

Bone (New York, N.Y.), 2020-10, Vol.139, p.115493, Article 115493

2020

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Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL

Nature genetics, 2007-08, Vol.39 (8), p.960-962

2007

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The bisphosphonate zoledronic acid has antimyeloma activity in vivo by inhibition of protein prenylation

International journal of cancer, 2010-01, Vol.126 (1), p.239-246

2010

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Defective Protein Prenylation in a Spectrum of Patients With Mevalonate Kinase Deficiency

Frontiers in immunology, 2019-08, Vol.10, p.1900-1900

2019

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Increased core body temperature exacerbates defective protein prenylation in mouse models of mevalonate kinase deficiency

The Journal of clinical investigation, 2022-10, Vol.132 (19), p.1-16

2022

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Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo

Journal of bone and mineral research, 2012-04, Vol.27 (4), p.835-847

2012

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From vesicle to cytosol

eLife, 2018-06, Vol.7

2018

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Mechanisms of osteopontin and CD44 as metastatic principles in prostate cancer cells

Molecular cancer, 2007-03, Vol.6 (1), p.18-18, Article 18

2007

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Synthesis and Characterization of Bone Binding Antibiotic-1 (BBA-1), a Novel Antimicrobial for Orthopedic Applications

Molecules (Basel, Switzerland), 2021-03, Vol.26 (6), p.1541

2021

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Cytosolic Entry of Bisphosphonate Drugs Requires Acidification of Vesicles after Fluid-Phase Endocytosis

Molecular pharmacology, 2006-05, Vol.69 (5), p.1624-1632

2006

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The regulation of osteoclast function and bone resorption by small GTPases

Small GTPases, 2011-05, Vol.2 (3), p.117-130

2011

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Inhibition of Protein Prenylation by Bisphosphonates Causes Sustained Activation of Rac, Cdc42, and Rho GTPases

Journal of bone and mineral research, 2006-05, Vol.21 (5), p.684-694

2006

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Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans

The Journal of clinical investigation, 2007-04, Vol.117 (4), p.919-930

2007

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Archaeology and the Origins of Human Cumulative Culture: A Case Study from the Earliest Oldowan at Gona, Ethiopia

Current anthropology, 2019-06, Vol.60 (3), p.309-340

2019

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Oxysterols: From physiological tuners to pharmacological opportunities

Biochemical and molecular mechanisms of action of bisphosphonates

Cellular and molecular mechanisms of action of bisphosphonates

putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

Molecular Mechanisms of Action of Bisphosphonates: Current Status

Technological variation in the earliest Oldowan from Gona, Afar, Ethiopia

Ardipithecus ramidus postcrania from the Gona Project area, Afar Regional State, Ethiopia

Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer

Estimating sexual size dimorphism in fossil species from posterior probability densities

Visualizing mineral binding and uptake of bisphosphonate by osteoclasts and non-resorbing cells

The Molecular Mechanism of Nitrogen-Containing Bisphosphonates as Antiosteoporosis Drugs

Molecular mechanisms of action of bisphosphonates and new insights into their effects outside the skeleton

Osteoclast-poor human osteopetrosis due to mutations in the gene encoding RANKL

The bisphosphonate zoledronic acid has antimyeloma activity in vivo by inhibition of protein prenylation

Defective Protein Prenylation in a Spectrum of Patients With Mevalonate Kinase Deficiency

Increased core body temperature exacerbates defective protein prenylation in mouse models of mevalonate kinase deficiency

Influence of bone affinity on the skeletal distribution of fluorescently labeled bisphosphonates in vivo

From vesicle to cytosol

Mechanisms of osteopontin and CD44 as metastatic principles in prostate cancer cells

Synthesis and Characterization of Bone Binding Antibiotic-1 (BBA-1), a Novel Antimicrobial for Orthopedic Applications

Cytosolic Entry of Bisphosphonate Drugs Requires Acidification of Vesicles after Fluid-Phase Endocytosis

The regulation of osteoclast function and bone resorption by small GTPases

Inhibition of Protein Prenylation by Bisphosphonates Causes Sustained Activation of Rac, Cdc42, and Rho GTPases

Involvement of PLEKHM1 in osteoclastic vesicular transport and osteopetrosis in incisors absent rats and humans

Archaeology and the Origins of Human Cumulative Culture: A Case Study from the Earliest Oldowan at Gona, Ethiopia

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