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Palladium Catalyzed Asymmetric Three-Component Coupling of Boronic Esters, Indoles, and Allylic Acetates

Journal of the American Chemical Society, 2017-05, Vol.139 (17), p.6038-6041

2017

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P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage

Cell, 2014-09, Vol.158 (6), p.1324-1334

2014

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Rhodium‐Catalyzed Enantioselective Radical Addition of CX4 Reagents to Olefins

Angewandte Chemie International Edition, 2017-07, Vol.56 (30), p.8780-8784

International ed. in English, 2017

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A Concise Total Synthesis of Dictyodendrins F, H, and I Using Aryl Ynol Ethers as Key Building Blocks

Journal of the American Chemical Society, 2016-08, Vol.138 (33), p.10684-10692

2016

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The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis

Molecular psychiatry, 2015-04, Vol.20 (4), p.500-508

2015

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Total synthesis of the dictyodendrins as an arena to highlight emerging synthetic technologies

Natural product reports, 2017-08, Vol.34 (8), p.11-134

2017

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[3 + 2]-Cycloadditions of Azomethine Imines and Ynolates

Organic letters, 2016-06, Vol.18 (11), p.2608-2611

2016

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Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

Science (American Association for the Advancement of Science), 2015-06, Vol.348 (6240), p.1223-1223

2015

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Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system

Nature communications, 2023-02, Vol.14 (1), p.784-13, Article 784

2023

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P7C3 Neuroprotective Chemicals Block Axonal Degeneration and Preserve Function after Traumatic Brain Injury

Cell reports (Cambridge), 2014-09, Vol.8 (6), p.1731-1740

2014

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Chiral Allene-Containing Phosphines in Asymmetric Catalysis

Journal of the American Chemical Society, 2011-11, Vol.133 (45), p.18066-18069

2011

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Highly Active Oligomeric (salen)Co Catalysts for Asymmetric Epoxide Ring-Opening Reactions

Journal of the American Chemical Society, 2001-03, Vol.123 (11), p.2687-2688

2001

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Synthesis of Cyclopentenones from Cyclopropanes and Silyl Ynol Ethers

Angewandte Chemie (International ed.), 2008-09, Vol.47 (37), p.7068-7070

2008

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Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency

Nature communications, 2024-07, Vol.15 (1), p.6125-20, Article 6125

2024

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Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (42), p.17010-17015

2012

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In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity

Journal of molecular biology, 2014-05, Vol.426 (10), p.2045-2058

2014

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Tandem Allylation/1,2-Boronate Rearrangement for the Asymmetric Synthesis of Indolines with Adjacent Quaternary Stereocenters

Journal of the American Chemical Society, 2018-10, Vol.140 (41), p.13242-13252

2018

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Iron-Catalyzed Carbometalation of Propargylic and Homopropargylic Alcohols

Journal of the American Chemical Society, 2006-11, Vol.128 (47), p.15050-15051

2006

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Enantioselective Total Synthesis of (−)-Kibdelone C

Journal of the American Chemical Society, 2011-07, Vol.133 (26), p.9956-9959

2011

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Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase

Nature chemical biology, 2016-04, Vol.12 (4), p.218-225

2016

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Inhibitors of 15-Prostaglandin Dehydrogenase To Potentiate Tissue Repair

Journal of medicinal chemistry, 2017-05, Vol.60 (9), p.3979-4001

2017

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A second-generation 15-PGDH inhibitor promotes bone marrow transplant recovery independently of age, transplant dose and granulocyte colony-stimulating factor support

Haematologica (Roma), 2018-06, Vol.103 (6), p.1054-1064

2018

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Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (42), p.17016-17021

2012

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A Virus-Packageable CRISPR System Identifies Host Dependency Factors Co-Opted by Multiple HIV-1 Strains

mBio, 2023-02, Vol.14 (1), p.e0000923-e0000923

2023

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Evolution of a Synthetic Strategy: Total Synthesis of (±)-Welwitindolinone A Isonitrile

Journal of the American Chemical Society, 2008-02, Vol.130 (6), p.2087-2100

2008

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Palladium Catalyzed Asymmetric Three-Component Coupling of Boronic Esters, Indoles, and Allylic Acetates

P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage

Rhodium‐Catalyzed Enantioselective Radical Addition of CX4 Reagents to Olefins

A Concise Total Synthesis of Dictyodendrins F, H, and I Using Aryl Ynol Ethers as Key Building Blocks

The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis

Total synthesis of the dictyodendrins as an arena to highlight emerging synthetic technologies

[3 + 2]-Cycloadditions of Azomethine Imines and Ynolates

Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration

Small molecule inhibitors of 15-PGDH exploit a physiologic induced-fit closing system

P7C3 Neuroprotective Chemicals Block Axonal Degeneration and Preserve Function after Traumatic Brain Injury

Chiral Allene-Containing Phosphines in Asymmetric Catalysis

Highly Active Oligomeric (salen)Co Catalysts for Asymmetric Epoxide Ring-Opening Reactions

Synthesis of Cyclopentenones from Cyclopropanes and Silyl Ynol Ethers

Benzoxazole-derivatives enhance progranulin expression and reverse the aberrant lysosomal proteome caused by GRN haploinsufficiency

Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease

In Silico Derived Small Molecules Bind the Filovirus VP35 Protein and Inhibit Its Polymerase Cofactor Activity

Tandem Allylation/1,2-Boronate Rearrangement for the Asymmetric Synthesis of Indolines with Adjacent Quaternary Stereocenters

Iron-Catalyzed Carbometalation of Propargylic and Homopropargylic Alcohols

Enantioselective Total Synthesis of (−)-Kibdelone C

Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase

Inhibitors of 15-Prostaglandin Dehydrogenase To Potentiate Tissue Repair

A second-generation 15-PGDH inhibitor promotes bone marrow transplant recovery independently of age, transplant dose and granulocyte colony-stimulating factor support

Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis

A Virus-Packageable CRISPR System Identifies Host Dependency Factors Co-Opted by Multiple HIV-1 Strains

Evolution of a Synthetic Strategy: Total Synthesis of (±)-Welwitindolinone A Isonitrile

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