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Model Evaluation of Continuous Data Pharmacometric Models: Metrics and Graphics

CPT: pharmacometrics and systems pharmacology, 2017-02, Vol.6 (2), p.87-109

2017

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Effect of Adherence as Measured by MEMS, Ritonavir Boosting, and CYP3A5 Genotype on Atazanavir Pharmacokinetics in Treatment-Naive HIV-Infected Patients

Clinical pharmacology and therapeutics, 2012-11, Vol.92 (5), p.575-583

2012

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Role of modelling and simulation in Phase I drug development

European journal of pharmaceutical sciences, 2001-05, Vol.13 (2), p.115-122

2001

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Population pharmacokinetics of single-dose amikacin in critically ill patients with suspected ventilator-associated pneumonia

European journal of clinical pharmacology, 2015-01, Vol.71 (1), p.75-83

2015

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Overview of model‐building strategies in population PK/PD analyses: 2002–2004 literature survey

British journal of clinical pharmacology, 2007-11, Vol.64 (5), p.603-612

2007

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A Pharmacokinetic-Viral Kinetic Model Describes the Effect of Alisporivir as Monotherapy or in Combination With Peg-IFN on Hepatitis C Virologic Response

Clinical pharmacology and therapeutics, 2014-11, Vol.96 (5), p.599-608

2014

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Modelling and simulation in the development and use of anti-cancer agents : An underused tool?

Journal of pharmacokinetics and pharmacodynamics, 2004-12, Vol.31 (6), p.419-440

2004

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Modeling the Kinetics of Release of Octreotide from Long‐Acting Formulations Injected Intramuscularly in Rabbits

Journal of pharmaceutical sciences, 2000-09, Vol.89 (9), p.1123-1133

2000

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Robust optimal design for the estimation of hyperparameters in population pharmacokinetics

Journal of pharmacokinetics and biopharmaceutics, 1998-12, Vol.26 (6), p.689-716

1998

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Statistical estimation of pharmacokinetic/dynamic variability

Clinical neuropharmacology, 1992, Vol.15 Suppl 1 Pt A, p.241A-242A

Mentre, F

1992

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Sparse sampling for assessment of drug exposure in toxicological studies

European journal of drug metabolism and pharmacokinetics, 1996-04, Vol.21 (2), p.105-111

1996

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Prediction of fluindione maintenance dosage hampered by large intraindividual variability

Therapeutic drug monitoring, 2000-12, Vol.22 (6), p.668-675

2000

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Optimization of individual and population designs using Splus

Journal of pharmacokinetics and pharmacodynamics, 2003-12, Vol.30 (6), p.417-443

2003

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Optimal sampling times for bayesian estimation of the pharmacokinetic parameters of nortriptyline during therapeutic drug monitoring

Journal of pharmacokinetics and biopharmaceutics, 1999-02, Vol.27 (1), p.85-101

1999

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Pharmacokinetic analysis of mizolastine in healthy young volunteers after single oral and intravenous doses : Noncompartmental approach and compartmental modeling

Journal of Pharmacokinetics and Biopharmaceutics, 1997-04, Vol.25 (2), p.125-147

1997

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Pharmacokinetic and pharmacodynamic modeling of mizolastine in healthy volunteers with an indirect response model

Clinical pharmacology and therapeutics, 2000-12, Vol.68 (6), p.647-657

2000

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Enhanced Saquinavir Exposure in Human Immunodeficiency Virus Type 1-Infected Patients with Diarrhea and/or Wasting Syndrome

Antimicrobial Agents and Chemotherapy, 2004-02, Vol.48 (2), p.538-545

2004

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Nonparametric estimation of population characteristics of the kinetics of lithium from observational and experimental data : individualization of chronic dosing regimen using a new Bayesian approach

Therapeutic drug monitoring, 1994-06, Vol.16 (3), p.258-269

1994

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Designing an optimal experiment for Bayesian estimation: application to the kinetics of iodine thyroid uptake

Statistics in medicine, 1994-01, Vol.13 (2), p.185-196

1994

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Relationship between exposure to zidovudine and decrease of P24 antigenemia in HIV-infected patients in monotherapy

Fundamental & clinical pharmacology, 2002-10, Vol.16 (5), p.347-352

2002

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Bayesian design criteria : computation, comparison, and application to a pharmacokinetic and a pharmacodynamic model

Journal of pharmacokinetics and biopharmaceutics, 1995-02, Vol.23 (1), p.101-125

1995

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Handling covariates in population pharmacokinetics

International journal of bio-medical computing, 1994-06, Vol.36 (1), p.25-33

1994

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Computer-assisted individual estimation of radioiodine thyroid uptake in Grave's disease

Computer methods and programs in biomedicine, 1993-05, Vol.40 (1), p.33-41

1993

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Hyperparameter Estimation Using Stochastic Approximation with Application to Population Pharmacokinetics

Biometrics, 1988-09, Vol.44 (3), p.673-683

1988

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A Two-Step Iterative Algorithm For Estimation In Nonlinear Mixed-Effect Models With An Evaluation In Population Pharmacokinetics

Journal of biopharmaceutical statistics, 1995-01, Vol.5 (2), p.141-158

1995

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Model Evaluation of Continuous Data Pharmacometric Models: Metrics and Graphics

Effect of Adherence as Measured by MEMS, Ritonavir Boosting, and CYP3A5 Genotype on Atazanavir Pharmacokinetics in Treatment-Naive HIV-Infected Patients

Role of modelling and simulation in Phase I drug development

Population pharmacokinetics of single-dose amikacin in critically ill patients with suspected ventilator-associated pneumonia

Overview of model‐building strategies in population PK/PD analyses: 2002–2004 literature survey

A Pharmacokinetic-Viral Kinetic Model Describes the Effect of Alisporivir as Monotherapy or in Combination With Peg-IFN on Hepatitis C Virologic Response

Modelling and simulation in the development and use of anti-cancer agents : An underused tool?

Modeling the Kinetics of Release of Octreotide from Long‐Acting Formulations Injected Intramuscularly in Rabbits

Robust optimal design for the estimation of hyperparameters in population pharmacokinetics

Statistical estimation of pharmacokinetic/dynamic variability

Sparse sampling for assessment of drug exposure in toxicological studies

Prediction of fluindione maintenance dosage hampered by large intraindividual variability

Optimization of individual and population designs using Splus

Optimal sampling times for bayesian estimation of the pharmacokinetic parameters of nortriptyline during therapeutic drug monitoring

Pharmacokinetic analysis of mizolastine in healthy young volunteers after single oral and intravenous doses : Noncompartmental approach and compartmental modeling

Pharmacokinetic and pharmacodynamic modeling of mizolastine in healthy volunteers with an indirect response model

Enhanced Saquinavir Exposure in Human Immunodeficiency Virus Type 1-Infected Patients with Diarrhea and/or Wasting Syndrome

Nonparametric estimation of population characteristics of the kinetics of lithium from observational and experimental data : individualization of chronic dosing regimen using a new Bayesian approach

Designing an optimal experiment for Bayesian estimation: application to the kinetics of iodine thyroid uptake

Relationship between exposure to zidovudine and decrease of P24 antigenemia in HIV-infected patients in monotherapy

Bayesian design criteria : computation, comparison, and application to a pharmacokinetic and a pharmacodynamic model

Handling covariates in population pharmacokinetics

Computer-assisted individual estimation of radioiodine thyroid uptake in Grave's disease

Hyperparameter Estimation Using Stochastic Approximation with Application to Population Pharmacokinetics

A Two-Step Iterative Algorithm For Estimation In Nonlinear Mixed-Effect Models With An Evaluation In Population Pharmacokinetics

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