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Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevance

Frontiers in genetics, 2013, Vol.4, p.24

2013

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MiR-155 and other microRNAs downregulate drug metabolizing cytochromes P450 in inflammation

Biochemical pharmacology, 2020-01, Vol.171, p.113725-113725, Article 113725

2020

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Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem

Frontiers in genetics, 2013, Vol.4, p.12

2013

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Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

Analytical and bioanalytical chemistry, 2008-11, Vol.392 (6), p.1093-1108

2008

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Tri‐Allelic Haplotypes Determine and Differentiate Functionally Normal Allele CYP2D62 and Impaired Allele CYP2D641

Clinical pharmacology and therapeutics, 2021-05, Vol.109 (5), p.1256-1264

2021

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Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver

Hepatology (Baltimore, Md.), 2009-10, Vol.50 (4), p.1227-1240

2009

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Saturated Fat-Mediated Upregulation of IL-32 and CCL20 in Hepatocytes Contributes to Higher Expression of These Fibrosis-Driving Molecules in MASLD

International journal of molecular sciences, 2023-09, Vol.24 (17), p.13222

2023

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Differential effects on human cytochromes P450 by CRISPR/Cas9-induced genetic knockout of cytochrome P450 reductase and cytochrome b5 in HepaRG cells

Scientific reports, 2021-01, Vol.11 (1), p.1000-1000, Article 1000

2021

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Role of Genetic and Nongenetic Factors for Fluorouracil Treatment-Related Severe Toxicity: A Prospective Clinical Trial by the German 5-FU Toxicity Study Group

Journal of clinical oncology, 2008-05, Vol.26 (13), p.2131-2138

2008

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Transcriptional profiling of human liver identifies sex-biased genes associated with polygenic dyslipidemia and coronary artery disease

PloS one, 2011-08, Vol.6 (8), p.e23506-e23506

2011

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Sustainable implementation of antibiotic stewardship on a surgical intensive care unit evaluated over a 10-year period

Infection, 2020-02, Vol.48 (1), p.117-124

2020

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Aberrant splicing caused by single nucleotide polymorphism c.516G>T [Q172H], a marker of CYP2B66, is responsible for decreased expression and activity of CYP2B6 in liver

The Journal of pharmacology and experimental therapeutics, 2008-04, Vol.325 (1), p.284

2008

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Aortic valve calcification is subject to aortic stenosis severity and the underlying flow pattern

Heart and vessels, 2021-02, Vol.36 (2), p.242-251

2021

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Direct transcriptional regulation of human hepatic cytochrome P450 3A4 (CYP3A4) by peroxisome proliferator-activated receptor alpha (PPARα)

Molecular pharmacology, 2013-03, Vol.83 (3), p.709-718

2013

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Function and Localization Dynamics of Bifunctional Penicillin-Binding Proteins in Caulobacter crescentus

Journal of bacteriology, 2014-04, Vol.196 (8), p.1627-1639

2014

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Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis

Frontiers in pharmacology, 2021-11, Vol.12, p.769703-769703

2021

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Abundance of DNA adducts of methyleugenol, a rodent hepatocarcinogen, in human liver samples

Carcinogenesis (New York), 2013-05, Vol.34 (5), p.1025-1030

2013

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A New Panel-Based Next-Generation Sequencing Method for ADME Genes Reveals Novel Associations of Common and Rare Variants With Expression in a Human Liver Cohort

Frontiers in genetics, 2019, Vol.10, p.7

2019

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Hepatic Expression of the Na+-Taurocholate Cotransporting Polypeptide Is Independent from Genetic Variation

International journal of molecular sciences, 2022-07, Vol.23 (13), p.7468

2022

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Carbonyl reductase 1 is a predominant doxorubicin reductase in the human liver

Drug metabolism and disposition, 2008-10, Vol.36 (10), p.2113

2008

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Interindividual variability of canalicular ATP‐binding‐cassette (ABC)–transporter expression in human liver

Hepatology (Baltimore, Md.), 2006-07, Vol.44 (1), p.62-74

2006

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Profiling induction of cytochrome p450 enzyme activity by statins using a new liquid chromatography-tandem mass spectrometry cocktail assay in human hepatocytes

Drug metabolism and disposition, 2010-09, Vol.38 (9), p.1589

2010

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Bioengineered Pancreas–Liver Crosstalk in a Microfluidic Coculture Chip Identifies Human Metabolic Response Signatures in Prediabetic Hyperglycemia

Advanced science, 2022-12, Vol.9 (34), p.e2203368-n/a

2022

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Pharmacogenomics of human liver cytochrome P450 oxidoreductase: multifactorial analysis and impact on microsomal drug oxidation

Pharmacogenomics, 2009-04, Vol.10 (4), p.579-599

2009

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Nanofluidic Immobilization and Growth Detection of Escherichia coli in a Chip for Antibiotic Susceptibility Testing

Biosensors (Basel), 2020-09, Vol.10 (10), p.135

2020

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