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Biochemical markers and the FDA Critical Path: How biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development

Biomarkers, 2009-05, Vol.14 (3), p.181-202

2009

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Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: From in vitro to in vivo

Analytical biochemistry, 2007-02, Vol.361 (1), p.93-101

2007

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An immunoaffinity liquid chromatography–tandem mass spectrometry assay for detection of endogenous aggrecan fragments in biological fluids: Use as a biomarker for aggrecanase activity and cartilage degradation

Analytical biochemistry, 2010-11, Vol.406 (2), p.113-123

2010

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Discovery and development of the N-terminal procollagen type II (NPII) biomarker: a tool for measuring collagen type II synthesis

Osteoarthritis and cartilage, 2008-12, Vol.16 (12), p.1494-1500

2008

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Determination of calcium binding sites in gas-phase small peptides by tandem mass spectrometry

Journal of the American Society for Mass Spectrometry, 1998-10, Vol.9 (10), p.1020-1028

1998

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Association between concentrations of urinary type II collagen neoepitope (uTIINE) and joint space narrowing in patients with knee osteoarthritis

Osteoarthritis and cartilage, 2006-11, Vol.14 (11), p.1189-1195

2006

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Electrospray ionization mass spectrometry and hydrogen/deuterium exchange for probing the interaction of calmodulin with calcium

Journal of the American Society for Mass Spectrometry, 1999-08, Vol.10 (8), p.711-718

1999

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Intrinsic Ca2+ affinities of peptides : Application of the kinetic method to analogs of calcium-binding site III of rabbit skeletal troponin C

Journal of the American Society for Mass Spectrometry, 2000-09, Vol.11 (9), p.770-779

2000

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Gas phase studies of the interactions of Fe2+ with cysteine-containing peptides

Journal of the American Society for Mass Spectrometry, 1998-12, Vol.9 (12), p.1285-1292

1998

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I-29 DISCOVERY AND VALIDATION OF AN IMMUNOAFFINITY LC-MS/MS ASSAY FOR THE QUANTIFICATION OF THE COLLAGEN TYPE II NEOEPITOPE PEPTIDE BIOMARKER

Osteoarthritis and cartilage, 2008, Vol.16, p.S9-S10

2008

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100 PREDICTING RADIOGRAPHIC JOINT SPACE NARROWING (JSN) USING BIOMARKERS FOR OSTEOARTHRITIS (OA) CLINICAL TRIALS

Osteoarthritis and cartilage, 2008, Vol.16, p.S56-S57

2008

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63 SEARCH FOR POTENTIAL OA OUTCOME BIOMARKERS – “MULTIMARKER APPROACH”

Osteoarthritis and cartilage, 2007, Vol.15, p.C48-C48

2007

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Do charge-remote fragmentations occur under matrix-assisted laser desorption ionization post-source decompositions and matrix-assisted laser desorption ionization collisionally activated decompositions?

Journal of the American Society for Mass Spectrometry, 1999-03, Vol.10 (3), p.217-223

1999

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Investigation of calcium-induced, noncovalent association of calmodulin with melittin by electrospray ionization mass spectrometry

Journal of the American Society for Mass Spectrometry, 1997-08, Vol.8 (8), p.809-812

1997

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High- and low-energy collisionally activated decompositions of octaethylporphyrin and its metal complexes

Journal of the American Society for Mass Spectrometry, 1998-08, Vol.9 (8), p.767-774

1998

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Complexes of iron(II) with cysteine-containing peptides in the gas phase

Journal of the American Society for Mass Spectrometry, 1996-09, Vol.7 (9), p.977-980

1996

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Differentiation of positional isomers of nitro meso-tetraphenylporphyrins by tandem mass spectrometry

Journal of the American Society for Mass Spectrometry, 2001-04, Vol.12 (4), p.381-384

2001

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Erratum to “Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: From in vitro to in vivo” [Anal. Biochem. 361 (2007) 93–113]

Analytical biochemistry, 2007-11, Vol.370 (2), p.258-258

2007

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P102 TYPE II COLLAGEN SYNTHESIS AND DEGRADATION BIOCHEMICAL MARKERS IN RELATION TO OSTEOARTHRITIS STATUS: A CROSS-SECTIONAL STUDY

Osteoarthritis and cartilage, 2006, Vol.14, p.S66-S67

2006

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Erratum to: Complexes of iron(ii) with cysteine-containing peptides in the gas phase

Journal of the American Society for Mass Spectrometry, 1997-02, Vol.8 (2), p.199-199

1997

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Electrospray ionization mass spectrometry and hydrogen/deuterium exchange for probing the interaction of calmodulin with calcium : Focus : H/D exchange of proteins in solution

Journal of the American Society for Mass Spectrometry, 1999, Vol.10 (8), p.711-718

1999

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Evaluation transversale de divers marqueurs biologiques du métabolisme du collagène du cartilage chez des sujets normaux et arthrosiques

Revue du rhumatisme (Ed. française : 1993), 2006-11, Vol.73 (10), p.1100-1100

2006

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Unexpected fragmentation of β-substituted meso-tetraphenylporphyrins induced by high-energy collisional activation

Journal of the American Society for Mass Spectrometry, 2002-12, Vol.13 (12), p.1427-1431

2002

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Modeling of operating modes of relay protection in electrical networks with insulated neutral

E3S Web of Conferences, 2021, Vol.288, p.1100

2021

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Comparative assessment of different methods of drying electric motors windings insulation

Vestnik MGTU, 2022-12, Vol.25 (4), p.354-364

2022

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Biochemical markers and the FDA Critical Path: How biomarkers may contribute to the understanding of pathophysiology and provide unique and necessary tools for drug development

Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: From in vitro to in vivo

An immunoaffinity liquid chromatography–tandem mass spectrometry assay for detection of endogenous aggrecan fragments in biological fluids: Use as a biomarker for aggrecanase activity and cartilage degradation

Discovery and development of the N-terminal procollagen type II (NPII) biomarker: a tool for measuring collagen type II synthesis

Determination of calcium binding sites in gas-phase small peptides by tandem mass spectrometry

Association between concentrations of urinary type II collagen neoepitope (uTIINE) and joint space narrowing in patients with knee osteoarthritis

Electrospray ionization mass spectrometry and hydrogen/deuterium exchange for probing the interaction of calmodulin with calcium

Intrinsic Ca2+ affinities of peptides : Application of the kinetic method to analogs of calcium-binding site III of rabbit skeletal troponin C

Gas phase studies of the interactions of Fe2+ with cysteine-containing peptides

I-29 DISCOVERY AND VALIDATION OF AN IMMUNOAFFINITY LC-MS/MS ASSAY FOR THE QUANTIFICATION OF THE COLLAGEN TYPE II NEOEPITOPE PEPTIDE BIOMARKER

100 PREDICTING RADIOGRAPHIC JOINT SPACE NARROWING (JSN) USING BIOMARKERS FOR OSTEOARTHRITIS (OA) CLINICAL TRIALS

63 SEARCH FOR POTENTIAL OA OUTCOME BIOMARKERS – “MULTIMARKER APPROACH”

Do charge-remote fragmentations occur under matrix-assisted laser desorption ionization post-source decompositions and matrix-assisted laser desorption ionization collisionally activated decompositions?

Investigation of calcium-induced, noncovalent association of calmodulin with melittin by electrospray ionization mass spectrometry

High- and low-energy collisionally activated decompositions of octaethylporphyrin and its metal complexes

Complexes of iron(II) with cysteine-containing peptides in the gas phase

Differentiation of positional isomers of nitro meso-tetraphenylporphyrins by tandem mass spectrometry

Erratum to “Discovery and development of a type II collagen neoepitope (TIINE) biomarker for matrix metalloproteinase activity: From in vitro to in vivo” [Anal. Biochem. 361 (2007) 93–113]

P102 TYPE II COLLAGEN SYNTHESIS AND DEGRADATION BIOCHEMICAL MARKERS IN RELATION TO OSTEOARTHRITIS STATUS: A CROSS-SECTIONAL STUDY

Erratum to: Complexes of iron(ii) with cysteine-containing peptides in the gas phase

Electrospray ionization mass spectrometry and hydrogen/deuterium exchange for probing the interaction of calmodulin with calcium : Focus : H/D exchange of proteins in solution

Evaluation transversale de divers marqueurs biologiques du métabolisme du collagène du cartilage chez des sujets normaux et arthrosiques

Unexpected fragmentation of β-substituted meso-tetraphenylporphyrins induced by high-energy collisional activation

Modeling of operating modes of relay protection in electrical networks with insulated neutral

Comparative assessment of different methods of drying electric motors windings insulation

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