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Inhibition of parvalbumin-expressing interneurons results in complex behavioral changes

Molecular psychiatry, 2015-12, Vol.20 (12), p.1499-1507

2015

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Maternal cariprazine exposure inhibits embryonic and postnatal brain cholesterol biosynthesis

Molecular psychiatry, 2020-11, Vol.25 (11), p.2685-2694

2020

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Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain

Journal of lipid research, 2022-08, Vol.63 (8), p.100249, Article 100249

2022

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Maternal aripiprazole exposure interacts with 7-dehydrocholesterol reductase mutations and alters embryonic neurodevelopment

Molecular psychiatry, 2019-04, Vol.24 (4), p.491-500

2019

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Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6

The Journal of neuroscience, 2007-10, Vol.27 (40), p.10695-10702

2007

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Immune system gene dysregulation in autism and schizophrenia

Developmental neurobiology (Hoboken, N.J.), 2012-10, Vol.72 (10), p.1277-1287

2012

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Temporal brain microRNA expression changes in a mouse model of neonatal hypoxic–ischemic injury

Pediatric research, 2022-01, Vol.91 (1), p.92-100

2022

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Vulnerability of DHCR7+/− mutation carriers to aripiprazole and trazodone exposure

Journal of lipid research, 2017-11, Vol.58 (11), p.2139-2146

2017

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Trazodone effects on developing brain

Translational psychiatry, 2021-02, Vol.11 (1), p.85-9, Article 85

2021

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Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients

Annals of neurology, 2006-03, Vol.59 (3), p.478-489

2006

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Chemical Inhibition of Sterol Biosynthesis

Biomolecules (Basel, Switzerland), 2024-04, Vol.14 (4), p.410

2024

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The Effect of Small Molecules on Sterol Homeostasis: Measuring 7‑Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts

Journal of medicinal chemistry, 2016-02, Vol.59 (3), p.1102-1115

2016

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The Genome in Three Dimensions: A New Frontier in Human Brain Research

Biological psychiatry (1969), 2014-06, Vol.75 (12), p.961-969

2014

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Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis

Toxicology and applied pharmacology, 2018-06, Vol.349, p.21-28

2018

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Medication effects on developmental sterol biosynthesis

Molecular psychiatry, 2022-01, Vol.27 (1), p.490-501

2022

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Immune System Disturbances in Schizophrenia

Biological psychiatry (1969), 2014-02, Vol.75 (4), p.316-323

2014

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Coordinated Messenger RNA/MicroRNA Changes in Fibroblasts of Patients with Major Depression

Biological psychiatry (1969), 2015-02, Vol.77 (3), p.256-265

2015

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Early Brain microRNA/mRNA Expression is Region-Specific After Neonatal Hypoxic-Ischemic Injury in a Mouse Model

Frontiers in genetics, 2022-02, Vol.13, p.841043

2022

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DHCEO accumulation is a critical mediator of pathophysiology in a Smith–Lemli–Opitz syndrome model

Neurobiology of disease, 2012-03, Vol.45 (3), p.923-929

2012

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Effects of Psychotropic Medication on Somatic Sterol Biosynthesis of Adult Mice

Biomolecules (Basel, Switzerland), 2022-10, Vol.12 (10), p.1535

2022

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Disruption of cerebral cortex MET signaling in autism spectrum disorder

Annals of neurology, 2007-09, Vol.62 (3), p.243-250

2007

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Schizophrenia as a Disorder of Molecular Pathways

Biological psychiatry (1969), 2015-01, Vol.77 (1), p.22-28

2015

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Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells[S]

Journal of lipid research, 2013-04, Vol.54 (4), p.1135-1143

2013

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Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex

Journal of neurodevelopmental disorders, 2018-06, Vol.10 (1), p.18-18, Article 18

2018

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Chronic Aripiprazole and Trazodone Polypharmacy Effects on Systemic and Brain Cholesterol Biosynthesis

Biomolecules (Basel, Switzerland), 2023-08, Vol.13 (9), p.1321

2023

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Inhibition of parvalbumin-expressing interneurons results in complex behavioral changes

Maternal cariprazine exposure inhibits embryonic and postnatal brain cholesterol biosynthesis

Individual and simultaneous treatment with antipsychotic aripiprazole and antidepressant trazodone inhibit sterol biosynthesis in the adult brain

Maternal aripiprazole exposure interacts with 7-dehydrocholesterol reductase mutations and alters embryonic neurodevelopment

Maternal Immune Activation Alters Fetal Brain Development through Interleukin-6

Immune system gene dysregulation in autism and schizophrenia

Temporal brain microRNA expression changes in a mouse model of neonatal hypoxic–ischemic injury

Vulnerability of DHCR7+/− mutation carriers to aripiprazole and trazodone exposure

Trazodone effects on developing brain

Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients

Chemical Inhibition of Sterol Biosynthesis

The Effect of Small Molecules on Sterol Homeostasis: Measuring 7‑Dehydrocholesterol in Dhcr7-Deficient Neuro2a Cells and Human Fibroblasts

The Genome in Three Dimensions: A New Frontier in Human Brain Research

Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis

Medication effects on developmental sterol biosynthesis

Immune System Disturbances in Schizophrenia

Coordinated Messenger RNA/MicroRNA Changes in Fibroblasts of Patients with Major Depression

Early Brain microRNA/mRNA Expression is Region-Specific After Neonatal Hypoxic-Ischemic Injury in a Mouse Model

DHCEO accumulation is a critical mediator of pathophysiology in a Smith–Lemli–Opitz syndrome model

Effects of Psychotropic Medication on Somatic Sterol Biosynthesis of Adult Mice

Disruption of cerebral cortex MET signaling in autism spectrum disorder

Schizophrenia as a Disorder of Molecular Pathways

Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells[S]

Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex

Chronic Aripiprazole and Trazodone Polypharmacy Effects on Systemic and Brain Cholesterol Biosynthesis

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