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Recent advances in understanding NRF2 as a druggable target: development of pro-electrophilic and non-covalent NRF2 activators to overcome systemic side effects of electrophilic drugs like dimethyl fumarate

F1000 research, 2017, Vol.6, p.2138-2138

2017

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Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs

Free radical biology & medicine, 2013-12, Vol.65, p.645-657

2013

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New prebiotics by ketone donation

Trends in endocrinology and metabolism, 2023-07, Vol.34 (7), p.414-425

Satoh, Takumi

2023

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Potential Therapeutic Use of the Rosemary Diterpene Carnosic Acid for Alzheimer's Disease, Parkinson's Disease, and Long-COVID through NRF2 Activation to Counteract the NLRP3 Inflammasome

Antioxidants, 2022-01, Vol.11 (1), p.124

2022

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Bird evolution by insulin resistance

Trends in endocrinology and metabolism, 2021-10, Vol.32 (10), p.803-813

Satoh, Takumi

2021

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Carnosic acid (CA) prevents lipid accumulation in hepatocytes through the EGFR/MAPK pathway

Journal of gastroenterology, 2012-07, Vol.47 (7), p.805-813

2012

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Redox regulation of neuronal survival mediated by electrophilic compounds

Trends in neurosciences (Regular ed.), 2007-01, Vol.30 (1), p.37-45

2007

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Zonarol, a sesquiterpene from the brown algae Dictyopteris undulata, provides neuroprotection by activating the Nrf2/ARE pathway

Biochemical and biophysical research communications, 2015-02, Vol.457 (4), p.718-722

2015

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Therapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer's disease models

Cell death & disease, 2016-12, Vol.7 (12), p.e2499-e2499

2016

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Pharmacokinetic Analysis of Zonarol, a Marine Algal Hydroquinone, in Mice Using HPLC with Fluorescence Detection

Antibiotics (Basel), 2023-06, Vol.12 (6), p.1013

2023

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Carnosic acid and carnosol inhibit adipocyte differentiation in mouse 3T3-L1 cells through induction of phase2 enzymes and activation of glutathione metabolism

Biochemical and biophysical research communications, 2009-05, Vol.382 (3), p.549-554

2009

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Compact Tunable Narrowband Terahertz-Wave Source Based on Difference Frequency Generation Pumped by Dual Fiber Lasers in MgO:LiNbO3

Journal of infrared, millimeter and terahertz waves, 2017-12, Vol.38 (12), p.1471-1476

2017

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Zonarol Protected Liver from Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Fatty Liver Disease in a Mouse Model

Nutrients, 2021-09, Vol.13 (10), p.3455

2021

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O2-inducible H2O2-forming NADPH oxidase is responsible for the hyper O2 sensitivity of Bifidobacterium longum subsp. infantis

Scientific reports, 2018-07, Vol.8 (1), p.1-10, Article 10750

2018

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Antiobesity Effects of Bifidobacterium breve Strain B-3 Supplementation in a Mouse Model with High-Fat Diet-Induced Obesity

Bioscience, biotechnology, and biochemistry, 2010, Vol.74 (8), p.1656-1661

2010

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Role of Nrf2 and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells

Journal of biochemistry (Tokyo), 2010-01, Vol.147 (1), p.73-81

2010

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Neonatal oral fluid as a transmission route for bifidobacteria to the infant gut immediately after birth

Scientific reports, 2019-06, Vol.9 (1), p.8692-9, Article 8692

2019

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Marine hydroquinone zonarol prevents inflammation and apoptosis in dextran sulfate sodium-induced mice ulcerative colitis

PloS one, 2014-11, Vol.9 (11), p.e113509

2014

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Protective effect of carnosic acid, a pro-electrophilic compound, in models of oxidative stress and light-induced retinal degeneration

Investigative ophthalmology & visual science, 2012-11, Vol.53 (12), p.7847-7854

2012

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Contribution of reduced and oxidized glutathione to signals detected by magnetic resonance spectroscopy as indicators of local brain redox state

Neuroscience research, 2006-05, Vol.55 (1), p.34-39

2006

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MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress

Proceedings of the National Academy of Sciences - PNAS, 2017-05, Vol.114 (20), p.E4048-E4056

2017

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Carnosic acid prevents obesity and hepatic steatosis in ob/ob mice

Hepatology research, 2011-01, Vol.41 (1), p.87-92

2011

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3-Hydroxybutyrate could serve as a principal energy substrate for human microbiota

Medical hypotheses, 2024-01, Vol.182, p.111217, Article 111217

2024

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Carnosic acid, a pro-electrophilic compound, inhibits LPS-induced activation of microglia

Biochemical and biophysical research communications, 2012-02, Vol.418 (1), p.22-26

2012

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Activated glutathione metabolism participates in protective effects of carnosic acid against oxidative stress in neuronal HT22 cells

Planta medica, 2010-05, Vol.76 (7), p.683

2010

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Recent advances in understanding NRF2 as a druggable target: development of pro-electrophilic and non-covalent NRF2 activators to overcome systemic side effects of electrophilic drugs like dimethyl fumarate

Nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs

New prebiotics by ketone donation

Potential Therapeutic Use of the Rosemary Diterpene Carnosic Acid for Alzheimer's Disease, Parkinson's Disease, and Long-COVID through NRF2 Activation to Counteract the NLRP3 Inflammasome

Bird evolution by insulin resistance

Carnosic acid (CA) prevents lipid accumulation in hepatocytes through the EGFR/MAPK pathway

Redox regulation of neuronal survival mediated by electrophilic compounds

Zonarol, a sesquiterpene from the brown algae Dictyopteris undulata, provides neuroprotection by activating the Nrf2/ARE pathway

Therapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer's disease models

Pharmacokinetic Analysis of Zonarol, a Marine Algal Hydroquinone, in Mice Using HPLC with Fluorescence Detection

Carnosic acid and carnosol inhibit adipocyte differentiation in mouse 3T3-L1 cells through induction of phase2 enzymes and activation of glutathione metabolism

Compact Tunable Narrowband Terahertz-Wave Source Based on Difference Frequency Generation Pumped by Dual Fiber Lasers in MgO:LiNbO3

Zonarol Protected Liver from Methionine- and Choline-Deficient Diet-Induced Nonalcoholic Fatty Liver Disease in a Mouse Model

O2-inducible H2O2-forming NADPH oxidase is responsible for the hyper O2 sensitivity of Bifidobacterium longum subsp. infantis

Antiobesity Effects of Bifidobacterium breve Strain B-3 Supplementation in a Mouse Model with High-Fat Diet-Induced Obesity

Role of Nrf2 and p62/ZIP in the neurite outgrowth by carnosic acid in PC12h cells

Neonatal oral fluid as a transmission route for bifidobacteria to the infant gut immediately after birth

Marine hydroquinone zonarol prevents inflammation and apoptosis in dextran sulfate sodium-induced mice ulcerative colitis

Protective effect of carnosic acid, a pro-electrophilic compound, in models of oxidative stress and light-induced retinal degeneration

Contribution of reduced and oxidized glutathione to signals detected by magnetic resonance spectroscopy as indicators of local brain redox state

MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress

Carnosic acid prevents obesity and hepatic steatosis in ob/ob mice

3-Hydroxybutyrate could serve as a principal energy substrate for human microbiota

Carnosic acid, a pro-electrophilic compound, inhibits LPS-induced activation of microglia

Activated glutathione metabolism participates in protective effects of carnosic acid against oxidative stress in neuronal HT22 cells

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