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Mechanisms of adaptation and progression in idiosyncratic drug induced liver injury, clinical implications

Liver international, 2016-02, Vol.36 (2), p.158-165

2016

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Differential Activation of Unconventional T Cells, Including iNKT Cells, in Alcohol‐Related Liver Disease

Alcoholism, clinical and experimental research, 2020-05, Vol.44 (5), p.1061-1074

2020

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Toll-Like Receptor 4 Mediates Alcohol-Induced Steatohepatitis Through Bone Marrow-Derived and Endogenous Liver Cells in Mice

Alcoholism, clinical and experimental research, 2011-08, Vol.35 (8), p.1509-1518

2011

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Neutrophil depletion protects against murine acetaminophen hepatotoxicity

Hepatology (Baltimore, Md.), 2006-06, Vol.43 (6), p.1220-1230

2006

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c-Jun N-Terminal Kinase Plays a Major Role in Murine Acetaminophen Hepatotoxicity

Gastroenterology (New York, N.Y. 1943), 2006-07, Vol.131 (1), p.165-178

2006

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Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria

Trends in pharmacological sciences (Regular ed.), 2013-04, Vol.34 (4), p.243-253

2013

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Questions and controversies: the role of necroptosis in liver disease

Cell death discovery, 2016-12, Vol.2 (1), p.16089-16089, Article 16089

2016

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Interaction of RIPK1 and A20 modulates MAPK signaling in murine acetaminophen toxicity

The Journal of biological chemistry, 2021-01, Vol.296, p.100300, Article 100300

2021

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Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity

Gastroenterology (New York, N.Y. 1943), 2004-12, Vol.127 (6), p.1760-1774

2004

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Targeting signal transduction pathways which regulate necrosis in acetaminophen hepatotoxicity

Journal of hepatology, 2015-07, Vol.63 (1), p.5-7

2015

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Celecoxib ameliorates portal hypertension of the cirrhotic rats through the dual inhibitory effects on the intrahepatic fibrosis and angiogenesis

PloS one, 2013-07, Vol.8 (7), p.e69309-e69309

2013

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Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors

Cell death & disease, 2024-02, Vol.15 (2), p.140-140, Article 140

2024

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Celecoxib attenuates hepatic cirrhosis through inhibition of epithelial-to-mesenchymal transition of hepatocytes

Journal of gastroenterology and hepatology, 2014-11, Vol.29 (11), p.1932-1942

2014

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Modulation of hepatic amyloid precursor protein and lipoprotein receptor-related protein 1 by chronic alcohol intake: Potential link between liver steatosis and amyloid-β

Frontiers in physiology, 2022-09, Vol.13, p.930402-930402

2022

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Differentiating between liver diseases by applying multiclass machine learning approaches to transcriptomics of liver tissue or blood-based samples

JHEP reports, 2022-10, Vol.4 (10), p.100560-100560, Article 100560

2022

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134 mNTX-250, a novel multimodal HPV-16 mRNA-based therapeutic, induces potent anti-tumor responses and establishes HPV-16 specific immune memory

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A154-A154

2023

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Identification of integrated proteomics and transcriptomics signature of alcohol-associated liver disease using machine learning

PLOS digital health, 2024-02, Vol.3 (2), p.e0000447

2024

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A murder mystery in the liver: who done it and how?

The Journal of clinical investigation, 2016-11, Vol.126 (11), p.4068-4071

2016

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Single-cell transcriptomics of peripheral blood mononuclear cells indicates impaired immune and inflammatory responses in alcohol-associated hepatitis

Human immunology, 2024-01, Vol.85 (1), p.110735-110735, Article 110735

2024

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How to Protect Against Acetaminophen: Don't Ask for JUNK

Gastroenterology (New York, N.Y. 1943), 2008-10, Vol.135 (4), p.1047-1051

2008

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Integrated Transcriptomic and Proteomic Analysis Identifies Plasma Biomarkers of Hepatocellular Failure in Alcohol-Associated Hepatitis

The American journal of pathology, 2022-12, Vol.192 (12), p.1658-1669

2022

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Role of innate immunity in acetaminophen-induced hepatotoxicity

Expert opinion on drug metabolism & toxicology, 2006-08, Vol.2 (4), p.493-503

2006

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Immune-mediated drug-induced liver disease

Clinics in liver disease, 2002-08, Vol.6 (3), p.755-774

2002

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Activated natural killer T cells induce liver injury by Fas and tumor necrosis factor-α during alcohol consumption

Gastroenterology (New York, N.Y. 1943), 2004-05, Vol.126 (5), p.1387-1399

2004

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Hepatitis C Virus Genotype 1b Core Protein Does Not Exert Immunomodulatory Effects on Virus-Induced Cellular Immunity

Journal of Virology, 2002-02, Vol.76 (3), p.990-997

2002

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Mechanisms of adaptation and progression in idiosyncratic drug induced liver injury, clinical implications

Differential Activation of Unconventional T Cells, Including iNKT Cells, in Alcohol‐Related Liver Disease

Toll-Like Receptor 4 Mediates Alcohol-Induced Steatohepatitis Through Bone Marrow-Derived and Endogenous Liver Cells in Mice

Neutrophil depletion protects against murine acetaminophen hepatotoxicity

c-Jun N-Terminal Kinase Plays a Major Role in Murine Acetaminophen Hepatotoxicity

Regulation of drug-induced liver injury by signal transduction pathways: critical role of mitochondria

Questions and controversies: the role of necroptosis in liver disease

Interaction of RIPK1 and A20 modulates MAPK signaling in murine acetaminophen toxicity

Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity

Targeting signal transduction pathways which regulate necrosis in acetaminophen hepatotoxicity

Celecoxib ameliorates portal hypertension of the cirrhotic rats through the dual inhibitory effects on the intrahepatic fibrosis and angiogenesis

Innate and adaptive immune cell interaction drives inflammasome activation and hepatocyte apoptosis in murine liver injury from immune checkpoint inhibitors

Celecoxib attenuates hepatic cirrhosis through inhibition of epithelial-to-mesenchymal transition of hepatocytes

Modulation of hepatic amyloid precursor protein and lipoprotein receptor-related protein 1 by chronic alcohol intake: Potential link between liver steatosis and amyloid-β

Differentiating between liver diseases by applying multiclass machine learning approaches to transcriptomics of liver tissue or blood-based samples

134 mNTX-250, a novel multimodal HPV-16 mRNA-based therapeutic, induces potent anti-tumor responses and establishes HPV-16 specific immune memory

Identification of integrated proteomics and transcriptomics signature of alcohol-associated liver disease using machine learning

A murder mystery in the liver: who done it and how?

Single-cell transcriptomics of peripheral blood mononuclear cells indicates impaired immune and inflammatory responses in alcohol-associated hepatitis

How to Protect Against Acetaminophen: Don't Ask for JUNK

Integrated Transcriptomic and Proteomic Analysis Identifies Plasma Biomarkers of Hepatocellular Failure in Alcohol-Associated Hepatitis

Role of innate immunity in acetaminophen-induced hepatotoxicity

Immune-mediated drug-induced liver disease

Activated natural killer T cells induce liver injury by Fas and tumor necrosis factor-α during alcohol consumption

Hepatitis C Virus Genotype 1b Core Protein Does Not Exert Immunomodulatory Effects on Virus-Induced Cellular Immunity

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