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Intracellular Metabolomics Identifies Efflux Transporter Inhibitors in a Routine Caco-2 Cell Permeability Assay-Biological Implications

Cells (Basel, Switzerland), 2022-10, Vol.11 (20), p.3286

2022

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Mild and Highly Chemoselective Oxidation of Thioethers Mediated by Sc(OTf)3

Organic letters, 2003-02, Vol.5 (3), p.235-237

2003

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Flexible Strategy for the Synthesis of Pyrrolizidine Alkaloids

Organic letters, 2008-08, Vol.10 (16), p.3615-3618

2008

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An Enzymatic Approach to the Desymmetrization of Disubstituted Pyrrolines

Journal of organic chemistry, 2006-08, Vol.71 (16), p.6298-6301

2006

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Singlet oxygen conversion of indoles into α,β-unsaturated oxindoles in model compounds related to the welwitindolinone alkaloids

Tetrahedron letters, 2009-07, Vol.50 (26), p.3283-3286

2009

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Potent and selective xanthine-based inhibitors of phosphodiesterase 5

Bioorganic & medicinal chemistry letters, 2007-04, Vol.17 (8), p.2376-2379

2007

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Increased prokineticin 2 expression in gut inflammation: role in visceral pain and intestinal ion transport

Neurogastroenterology and motility, 2012-01, Vol.24 (1), p.65-e12

2012

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Development of TRPC Assays on Automated Electrophysiology Platforms

Biophysical journal, 2014-01, Vol.106 (2), p.753a-753a

2014

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Bridgehead enolates and bridgehead alkenes in a welwistatin model series

Chemical communications (Cambridge, England), 2009-01 (11), p.1398-1400

2009

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CHAPTER 9 - TRPV1 Antagonism: From Research to Clinic

Ion Channel Drug Discovery, 2015, p.186-237

2015

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The development of automated patch clamp assays for canonical transient receptor potential channels TRPC3, 6, and 7

Assay and drug development technologies, 2014-06, Vol.12 (5), p.282-292

2014

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Cystine mimetics––solid phase lanthionine synthesis

Tetrahedron letters, 2004-02, Vol.45 (7), p.1399-1401

2004

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Design and synthesis of a library of chemokine antagonists

Bioorganic & medicinal chemistry letters, 2011-11, Vol.21 (21), p.6249-6252

2011

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Supported Reagents: Opportunities and Limitations

Synlett, 2000, Vol.2000 (12), p.1846-1859

2000

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Dyad beads and the combinatorial discovery of catalystsIain Linguard, PhD Thesis, University of Southampton, September 2002

Chemical communications (Cambridge, England), 2003-09 (18), p.2310

2003

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Dyad beads and the combinatorial discovery of catalysts

Chemical communications (Cambridge, England), 2003-09 (18), p.2310-2311

2003

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Multiple solid-phase synthesis of hydantoins and thiohydantoins

Molecular diversity, 1997, Vol.3 (3), p.195-198

1997

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1,3-Dipolar cycloaddition route to nitrogen heterocyclic triones

Journal of the Chemical Society, Perkin Transactions 1, 1999 (7), p.765-776

1999

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Hexadienyloxycarbonyl (Hdoc) - A Mild Acid Labile Protecting Group for Amines

Synlett, 2003, Vol.2003 (12), p.1791-1792

2003

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2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists

Bioorganic & medicinal chemistry letters, 2007-08, Vol.17 (15), p.4347-4350

2007

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Enantioselective Partial Reduction of 2,5-Disubstituted Pyrroles via a Chiral Protonation Approach

Organic letters, 2004-09, Vol.6 (18), p.3055-3058

2004

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A solid-phase approach towards the synthesis of PDE5 inhibitors

Bioorganic & medicinal chemistry letters, 2002-08, Vol.12 (15), p.1973-1976

2002

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A combinatorial approach to the synthesis of cystine based organogelators

Journal of peptide science, 2004-06, Vol.10 (6), p.318-325

2004

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A formal synthesis of (−)-pumiliotoxin C

Tetrahedron: asymmetry, 1996-06, Vol.7 (6), p.1595-1596

1996

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An isoxazole route to unsaturated α-alkoxycarbonyl-β-diketones

J. Chem. Soc., Perkin Trans. 1, 1993 (15), p.1715-1716

1993

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Intracellular Metabolomics Identifies Efflux Transporter Inhibitors in a Routine Caco-2 Cell Permeability Assay-Biological Implications

Mild and Highly Chemoselective Oxidation of Thioethers Mediated by Sc(OTf)3

Flexible Strategy for the Synthesis of Pyrrolizidine Alkaloids

An Enzymatic Approach to the Desymmetrization of Disubstituted Pyrrolines

Singlet oxygen conversion of indoles into α,β-unsaturated oxindoles in model compounds related to the welwitindolinone alkaloids

Potent and selective xanthine-based inhibitors of phosphodiesterase 5

Increased prokineticin 2 expression in gut inflammation: role in visceral pain and intestinal ion transport

Development of TRPC Assays on Automated Electrophysiology Platforms

Bridgehead enolates and bridgehead alkenes in a welwistatin model series

CHAPTER 9 - TRPV1 Antagonism: From Research to Clinic

The development of automated patch clamp assays for canonical transient receptor potential channels TRPC3, 6, and 7

Cystine mimetics––solid phase lanthionine synthesis

Design and synthesis of a library of chemokine antagonists

Supported Reagents: Opportunities and Limitations

Dyad beads and the combinatorial discovery of catalystsIain Linguard, PhD Thesis, University of Southampton, September 2002

Dyad beads and the combinatorial discovery of catalysts

Multiple solid-phase synthesis of hydantoins and thiohydantoins

1,3-Dipolar cycloaddition route to nitrogen heterocyclic triones

Hexadienyloxycarbonyl (Hdoc) - A Mild Acid Labile Protecting Group for Amines

2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists

Enantioselective Partial Reduction of 2,5-Disubstituted Pyrroles via a Chiral Protonation Approach

A solid-phase approach towards the synthesis of PDE5 inhibitors

A combinatorial approach to the synthesis of cystine based organogelators

A formal synthesis of (−)-pumiliotoxin C

An isoxazole route to unsaturated α-alkoxycarbonyl-β-diketones

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