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Improved production of class I phosphatidylinositol 4,5-bisphosphate 3-kinase

Protein expression and purification, 2025-01, Vol.225, p.106582, Article 106582

2025

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The role and mechanism of NRG1/ErbB4 in inducing the differentiation of induced pluripotent stem cells into cardiomyocytes

BMC cardiovascular disorders, 2024-10, Vol.24 (1), p.559-12, Article 559

2024

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The Worsening of Myocardial Ischemia-Reperfusion Injury in Uremic Cardiomyopathy is Further Aggravated by PM 2.5 Exposure: Mitochondria Serve as the Central Focus of Pathology

Cardiovascular toxicology, 2024-11, Vol.24 (11), p.1236

2024

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Therapeutic potential of inhibiting the PI3Kγ complex for leukemia

Cell chemical biology, 2024-07, Vol.31 (7), p.1244

2024

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The class III phosphatidylinositol 3-kinase VPS34 supports EV71 replication by promoting viral replication organelle formation

Journal of virology, 2024-10, Vol.98 (10), p.e0069524

2024

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Pericyte-to-Endothelial Cell Communication via Tunneling Nanotubes Is Disrupted by a Diol of Docosahexaenoic Acid

Cells (Basel, Switzerland), 2024-08, Vol.13 (17), p.1429

2024

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Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function

Science (American Association for the Advancement of Science), 2024-10, Vol.386 (6720), p.eadk9167

2024

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CHF6523 data suggest that the phosphoinositide 3-kinase delta isoform is not a suitable target for the management of COPD

Respiratory research, 2024-10, Vol.25 (1), p.380-13, Article 380

2024

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Exploring the environmental contamination toxicity and potential carcinogenic pathways of perfluorinated and polyfluoroalkyl substances (PFAS): An integrated network toxicology and molecular docking strategy

Heliyon, 2024-09, Vol.10 (17), p.e37003, Article e37003

2024

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Electroacupuncture regulates glucose metabolism by inhibiting SGLT1 levels, inhibiting microglial polarization, and alleviating Parkinson's disease

Experimental gerontology, 2024-10, Vol.196, p.112558, Article 112558

2024

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Effects of Target of Rapamycin and Phosphatidylinositol 3-Kinase Inhibitors and Other Autophagy-Related Supplements on Life Span in y w Male Drosophila melanogaster

International journal of molecular sciences, 2024-11, Vol.25 (21), p.11504

2024

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Subunit-Specific Developmental Roles of PI3K in SF1-Expressing Cells

Endocrinology and metabolism (Seoul), 2024-10, Vol.39 (5), p.793

2024

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A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease

Nature communications, 2024-08, Vol.15 (1), p.7181-21

2024

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Hippo effector, Yorkie, is a tumor suppressor in select Drosophila squamous epithelia

Proceedings of the National Academy of Sciences - PNAS, 2024-09, Vol.121 (39), p.e2319666121

2024

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Diosgenin Alleviates Obesity-Induced Insulin Resistance by Modulating PI3K/Akt Signaling Pathway in Mice Fed a High-Fat Diet

Chemical and Pharmaceutical Bulletin, 2024/10/01, Vol.72(10), pp.845-855

2024

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Germline mutations in a G protein identify signaling cross-talk in T cells

Science (American Association for the Advancement of Science), 2024-09, Vol.385 (6715), p.eadd8947

2024

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Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy

Nature communications, 2024-08, Vol.15 (1), p.7194-15, Article 7194

2024

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Integrative analysis of multi-omics data reveals importance of collagen and the PI3K AKT signalling pathway in CAKUT

Scientific reports, 2024-09, Vol.14 (1), p.20731-12, Article 20731

2024

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Nesfatin-1 regulates the phenotype transition of cavernous smooth muscle cells by activating PI3K/AKT/mTOR signaling pathway to improve diabetic erectile dysfunction

PloS one, 2024-09, Vol.19 (9), p.e0304485

2024

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Functional activation of the AKT-mTOR signalling axis in a real-world metastatic breast cancer cohort

British journal of cancer, 2024-11, Vol.131 (9), p.1543-1554

2024

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AMBRA1 controls the translation of immune-specific genes in T lymphocytes

Proceedings of the National Academy of Sciences - PNAS, 2024-10, Vol.121 (44), p.e2416722121

2024

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Rabex-5 E3 and Rab5 GEF domains differ in their regulation of Ras, Notch, and PI3K signaling in Drosophila wing development

PloS one, 2024-10, Vol.19 (10), p.e0312274

2024

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Crosstalk between MIR-96 and IRS/PI3K/AKT/VEGF cascade in hRPE cells; A potential target for preventing diabetic retinopathy

PloS one, 2024-09, Vol.19 (9), p.e0310999

2024

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A single center experience on PI3K/AKT/MTOR signaling defects: Towards pathogenicity assessment for four novel defects

Pediatric allergy and immunology, 2024-09, Vol.35 (9), p.e14245

2024

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Monocarboxylate transporter dependent mechanism is involved in proliferation, migration, and invasion of human glioblastoma cell lines via activation of PI3K/Akt signaling pathway

PloS one, 2024-10, Vol.19 (10), p.e0312939

2024

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Improved production of class I phosphatidylinositol 4,5-bisphosphate 3-kinase

The role and mechanism of NRG1/ErbB4 in inducing the differentiation of induced pluripotent stem cells into cardiomyocytes

The Worsening of Myocardial Ischemia-Reperfusion Injury in Uremic Cardiomyopathy is Further Aggravated by PM 2.5 Exposure: Mitochondria Serve as the Central Focus of Pathology

Therapeutic potential of inhibiting the PI3Kγ complex for leukemia

The class III phosphatidylinositol 3-kinase VPS34 supports EV71 replication by promoting viral replication organelle formation

Pericyte-to-Endothelial Cell Communication via Tunneling Nanotubes Is Disrupted by a Diol of Docosahexaenoic Acid

Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function

CHF6523 data suggest that the phosphoinositide 3-kinase delta isoform is not a suitable target for the management of COPD

Exploring the environmental contamination toxicity and potential carcinogenic pathways of perfluorinated and polyfluoroalkyl substances (PFAS): An integrated network toxicology and molecular docking strategy

Electroacupuncture regulates glucose metabolism by inhibiting SGLT1 levels, inhibiting microglial polarization, and alleviating Parkinson's disease

Effects of Target of Rapamycin and Phosphatidylinositol 3-Kinase Inhibitors and Other Autophagy-Related Supplements on Life Span in y w Male Drosophila melanogaster

Subunit-Specific Developmental Roles of PI3K in SF1-Expressing Cells

A class I PI3K signalling network regulates primary cilia disassembly in normal physiology and disease

Hippo effector, Yorkie, is a tumor suppressor in select Drosophila squamous epithelia

Diosgenin Alleviates Obesity-Induced Insulin Resistance by Modulating PI3K/Akt Signaling Pathway in Mice Fed a High-Fat Diet

Germline mutations in a G protein identify signaling cross-talk in T cells

Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy

Integrative analysis of multi-omics data reveals importance of collagen and the PI3K AKT signalling pathway in CAKUT

Nesfatin-1 regulates the phenotype transition of cavernous smooth muscle cells by activating PI3K/AKT/mTOR signaling pathway to improve diabetic erectile dysfunction

Functional activation of the AKT-mTOR signalling axis in a real-world metastatic breast cancer cohort

AMBRA1 controls the translation of immune-specific genes in T lymphocytes

Rabex-5 E3 and Rab5 GEF domains differ in their regulation of Ras, Notch, and PI3K signaling in Drosophila wing development

Crosstalk between MIR-96 and IRS/PI3K/AKT/VEGF cascade in hRPE cells; A potential target for preventing diabetic retinopathy

A single center experience on PI3K/AKT/MTOR signaling defects: Towards pathogenicity assessment for four novel defects

Monocarboxylate transporter dependent mechanism is involved in proliferation, migration, and invasion of human glioblastoma cell lines via activation of PI3K/Akt signaling pathway

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