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Global histone H2B degradation regulates insulin/IGF signaling-mediated nutrient stress

The EMBO journal, 2023-10, Vol.42 (19), p.e113328-e113328

2023

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Insulin/IGF signaling in Drosophila and other insects: factors that regulate production, release and post-release action of the insulin-like peptides

Cellular and molecular life sciences : CMLS, 2016-01, Vol.73 (2), p.271-290

2016

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Keeping IGF-II under control: Lessons from the IGF-II–IGF2R crystal structure

Trends in biochemical sciences (Amsterdam. Regular ed.), 2009-12, Vol.34 (12), p.612-619

2009

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Mechano-transduction in Osteoblastic Cells Involves Strain-regulated Estrogen Receptor α-mediated Control of Insulin-like Growth Factor (IGF) I Receptor Sensitivity to Ambient IGF, Leading to Phosphatidylinositol 3-Kinase/AKT-dependent Wnt/LRP5 Receptor-independent Activation of β-Catenin Signaling

The Journal of biological chemistry, 2010-03, Vol.285 (12), p.8743-8758

2010

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Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

The FASEB journal, 2014-03, Vol.28 (3), p.1294-1305

2014

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The Insulin/IGF System in Mammalian Sexual Development and Reproduction

International journal of molecular sciences, 2019-09, Vol.20 (18), p.4440

2019

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Insulin-like Growth Factor-II (IGF-II) and IGF-II Analogs with Enhanced Insulin Receptor-a Binding Affinity Promote Neural Stem Cell Expansion

The Journal of biological chemistry, 2014-02, Vol.289 (8), p.4626-4633

2014

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IGF‐I protects porcine granulosa cells from hypoxia‐induced apoptosis by promoting homologous recombination repair through the PI3K/AKT/E2F8/RAD51 pathway

The FASEB journal, 2024-01, Vol.38 (1), p.e23332-n/a

2024

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The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

Nature medicine, 2012-11, Vol.18 (11), p.1643-1650

2012

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Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation

FEBS letters, 2002-07, Vol.522 (1), p.156-160

2002

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Molecular interactions of the IGF system

Cytokine & growth factor reviews, 2005-08, Vol.16 (4), p.421-439

2005

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Roles of α-linolenic acid on IGF-I secretion and GH/IGF system gene expression in porcine primary hepatocytes

Molecular biology reports, 2012-12, Vol.39 (12), p.10987-10996

2012

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Inflammatory Diseases and Growth: Effects on the GH-IGF Axis and on Growth Plate

International journal of molecular sciences, 2017-08, Vol.18 (9), p.1878

2017

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The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK⁺ T-cell lymphoma

Molecular cancer, 2015-02, Vol.14 (1), p.53-53, Article 53

2015

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β-catenin/LEF1/IGF-IIR Signaling Axis Galvanizes the Angiotensin-II- induced Cardiac Hypertrophy

International journal of molecular sciences, 2019-09, Vol.20 (17), p.4288

2019

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Insulin/IGF-driven cancer cell-stroma crosstalk as a novel therapeutic target in pancreatic cancer

Molecular cancer, 2018-02, Vol.17 (1), p.66-66, Article 66

2018

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IGF Signaling in the Heart in Health and Disease

Biochemistry (Moscow), 2024-08, Vol.89 (8), p.1402-1428

2024

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Insulin/IGF-like signalling, the central nervous system and aging

Biochemical journal, 2009-02, Vol.418 (1), p.1-12

2009

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How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor

Structure (London), 2020-07, Vol.28 (7), p.786-798.e6

2020

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Impaired myoblast differentiation and muscle IGF‐1 receptor signaling pathway activation after N‐glycosylation inhibition

The FASEB journal, 2024-07, Vol.38 (13), p.e23797-n/a

2024

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Ohwia caudata inhibits doxorubicin‐induced cardiotoxicity by regulating mitochondrial dynamics via the IGF‐IIR/p‐Drp1/PARP signaling pathway

Biotechnology and applied biochemistry, 2024-10, Vol.71 (5), p.1181-1194

2024

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Deletion of muscle IGF‐I transiently impairs growth and progressively disrupts glucose homeostasis in male mice

The FASEB journal, 2019-01, Vol.33 (1), p.181-194

2019

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Insulin/IGF Signaling and Vitellogenin Provisioning Mediate Intergenerational Adaptation to Nutrient Stress

Current biology, 2019-07, Vol.29 (14), p.2380-2388.e5

2019

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IGF signaling pathway in bone and cartilage development, homeostasis, and disease

The FASEB journal, 2024-09, Vol.38 (17), p.e70031-n/a

2024

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Activation of the IGF Axis in Thyroid Cancer: Implications for Tumorigenesis and Treatment

International journal of molecular sciences, 2019-07, Vol.20 (13), p.3258

2019

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Global histone H2B degradation regulates insulin/IGF signaling-mediated nutrient stress

Insulin/IGF signaling in Drosophila and other insects: factors that regulate production, release and post-release action of the insulin-like peptides

Keeping IGF-II under control: Lessons from the IGF-II–IGF2R crystal structure

Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

The Insulin/IGF System in Mammalian Sexual Development and Reproduction

Insulin-like Growth Factor-II (IGF-II) and IGF-II Analogs with Enhanced Insulin Receptor-a Binding Affinity Promote Neural Stem Cell Expansion

IGF‐I protects porcine granulosa cells from hypoxia‐induced apoptosis by promoting homologous recombination repair through the PI3K/AKT/E2F8/RAD51 pathway

The sirtuin SIRT6 blocks IGF-Akt signaling and development of cardiac hypertrophy by targeting c-Jun

Different roles of the IGF-I Ec peptide (MGF) and mature IGF-I in myoblast proliferation and differentiation

Molecular interactions of the IGF system

Roles of α-linolenic acid on IGF-I secretion and GH/IGF system gene expression in porcine primary hepatocytes

Inflammatory Diseases and Growth: Effects on the GH-IGF Axis and on Growth Plate

The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK⁺ T-cell lymphoma

β-catenin/LEF1/IGF-IIR Signaling Axis Galvanizes the Angiotensin-II- induced Cardiac Hypertrophy

Insulin/IGF-driven cancer cell-stroma crosstalk as a novel therapeutic target in pancreatic cancer

IGF Signaling in the Heart in Health and Disease

Insulin/IGF-like signalling, the central nervous system and aging

How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor

Impaired myoblast differentiation and muscle IGF‐1 receptor signaling pathway activation after N‐glycosylation inhibition

Ohwia caudata inhibits doxorubicin‐induced cardiotoxicity by regulating mitochondrial dynamics via the IGF‐IIR/p‐Drp1/PARP signaling pathway

Deletion of muscle IGF‐I transiently impairs growth and progressively disrupts glucose homeostasis in male mice

Insulin/IGF Signaling and Vitellogenin Provisioning Mediate Intergenerational Adaptation to Nutrient Stress

IGF signaling pathway in bone and cartilage development, homeostasis, and disease

Activation of the IGF Axis in Thyroid Cancer: Implications for Tumorigenesis and Treatment

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