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Id1-Induced IGF-II and Its Autocrine/Endocrine Promotion of Esophageal Cancer Progression and Chemoresistance-Implications for IGF-II and IGF-IR-Targeted Therapy

Clinical cancer research, 2014-05, Vol.20 (10), p.2651-2662

2014

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IGF-dependent and IGF-independent actions of IGF-binding protein-1 and -2: implications for metabolic homeostasis

Trends in endocrinology and metabolism, 2009-05, Vol.20 (4), p.153-162

2009

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MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors

Molecular cancer therapeutics, 2014-02, Vol.13 (2), p.410-425

2014

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The impact of a human IGF-II analog ([Leu27]IGF-II) on fetal growth in a mouse model of fetal growth restriction

American journal of physiology: endocrinology and metabolism, 2016-01, Vol.310 (1), p.E24-E31

2016

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Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins: Roles in skeletal muscle growth and differentiation

General and comparative endocrinology, 2010-07, Vol.167 (3), p.344-351

2010

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Gli1+ progenitors mediate bone anabolic function of teriparatide via Hh and Igf signaling

Cell reports (Cambridge), 2021-08, Vol.36 (7), p.109542-109542, Article 109542

2021

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IGF binding proteins in cancer: mechanistic and clinical insights

Nature reviews. Cancer, 2014-05, Vol.14 (5), p.329-341

Baxter, Robert C

2014

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Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease

Journal of Alzheimer's disease, 2017-01, Vol.55 (2), p.849-864

2017

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Detection of LongR 3 -IGF-I, Des(1-3)-IGF-I, and R 3 -IGF-I using immunopurification and high resolution mass spectrometry for antidoping purposes

Drug testing and analysis, 2021-07, Vol.13 (7), p.1256-1269

2021

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The IGF system

Acta diabetologica, 2011-03, Vol.48 (1), p.1-9

2011

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Global histone H2B degradation regulates insulin/IGF signaling-mediated nutrient stress

The EMBO journal, 2023-10, Vol.42 (19), p.e113328-e113328

2023

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Central IGF‐I Receptors in the Brain are Instrumental to Neuroprotection by Systemically Injected IGF‐I in a Rat Model for Ischemic Stroke

CNS neuroscience & therapeutics, 2016-07, Vol.22 (7), p.611-616

2016

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Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses

Oncotarget, 2015-06, Vol.6 (18), p.16084-16105

2015

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Insulin/IGF signaling in Drosophila and other insects: factors that regulate production, release and post-release action of the insulin-like peptides

Cellular and molecular life sciences : CMLS, 2016-01, Vol.73 (2), p.271-290

2016

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The expression of IGFs and IGF binding proteins in human carotid atherosclerosis, and the possible role of IGF binding protein-1 in the regulation of smooth muscle cell proliferation

Atherosclerosis, 2012-01, Vol.220 (1), p.102-109

2012

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Therapeutic Targeting of the IGF Axis

Cells (Basel, Switzerland), 2019-08, Vol.8 (8), p.895

2019

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Keeping IGF-II under control: Lessons from the IGF-II–IGF2R crystal structure

Trends in biochemical sciences (Amsterdam. Regular ed.), 2009-12, Vol.34 (12), p.612-619

2009

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Endothelial cells and the IGF system

Journal of molecular endocrinology, 2015-02, Vol.54 (1), p.R1-R13

Bach, Leon A

2015

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Effects of fasting on IGF-I, IGF-II, and IGF-binding protein mRNA concentrations in channel catfish ( Ictalurus punctatus)

Domestic animal endocrinology, 2009-08, Vol.37 (2), p.74-83

2009

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In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase

Cancer cell, 2004-03, Vol.5 (3), p.231-239

2004

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Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

The FASEB journal, 2014-03, Vol.28 (3), p.1294-1305

2014

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Insulin-like Growth Factor-II (IGF-II) and IGF-II Analogs with Enhanced Insulin Receptor-a Binding Affinity Promote Neural Stem Cell Expansion

The Journal of biological chemistry, 2014-02, Vol.289 (8), p.4626-4633

2014

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Metabolic and mitogenic effects of IGF-II in rainbow trout ( Oncorhynchus mykiss ) myocytes in culture and the role of IGF-II in the PI3K/Akt and MAPK signalling pathways

General and comparative endocrinology, 2008-06, Vol.157 (2), p.116-124

2008

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Expression of mRNA Encoding IGF-I, IGF-II, Type-I, and II IGF-Receptors and IGF-Binding Proteins-1-4 during Ovarian Follicular Development in Buffalo (Bubalus bubalis)

Animal biotechnology, 2015-04, Vol.26 (2), p.81-91

2015

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Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function during aging

Aging cell, 2015-10, Vol.14 (5), p.847-856

2015

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Id1-Induced IGF-II and Its Autocrine/Endocrine Promotion of Esophageal Cancer Progression and Chemoresistance-Implications for IGF-II and IGF-IR-Targeted Therapy

IGF-dependent and IGF-independent actions of IGF-binding protein-1 and -2: implications for metabolic homeostasis

MM-141, an IGF-IR- and ErbB3-directed bispecific antibody, overcomes network adaptations that limit activity of IGF-IR inhibitors

The impact of a human IGF-II analog ([Leu27]IGF-II) on fetal growth in a mouse model of fetal growth restriction

Insulin-like growth factors (IGFs), IGF receptors, and IGF-binding proteins: Roles in skeletal muscle growth and differentiation

Gli1+ progenitors mediate bone anabolic function of teriparatide via Hh and Igf signaling

IGF binding proteins in cancer: mechanistic and clinical insights

Improved Brain Insulin/IGF Signaling and Reduced Neuroinflammation with T3D-959 in an Experimental Model of Sporadic Alzheimer's Disease

Detection of LongR 3 -IGF-I, Des(1-3)-IGF-I, and R 3 -IGF-I using immunopurification and high resolution mass spectrometry for antidoping purposes

The IGF system

Global histone H2B degradation regulates insulin/IGF signaling-mediated nutrient stress

Central IGF‐I Receptors in the Brain are Instrumental to Neuroprotection by Systemically Injected IGF‐I in a Rat Model for Ischemic Stroke

Novel cross talk between IGF-IR and DDR1 regulates IGF-IR trafficking, signaling and biological responses

Insulin/IGF signaling in Drosophila and other insects: factors that regulate production, release and post-release action of the insulin-like peptides

The expression of IGFs and IGF binding proteins in human carotid atherosclerosis, and the possible role of IGF binding protein-1 in the regulation of smooth muscle cell proliferation

Therapeutic Targeting of the IGF Axis

Keeping IGF-II under control: Lessons from the IGF-II–IGF2R crystal structure

Endothelial cells and the IGF system

Effects of fasting on IGF-I, IGF-II, and IGF-binding protein mRNA concentrations in channel catfish ( Ictalurus punctatus)

In vivo antitumor activity of NVP-AEW541—A novel, potent, and selective inhibitor of the IGF-IR kinase

Down‐regulation of placental mTOR, insulin/IGF‐I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon

Insulin-like Growth Factor-II (IGF-II) and IGF-II Analogs with Enhanced Insulin Receptor-a Binding Affinity Promote Neural Stem Cell Expansion

Metabolic and mitogenic effects of IGF-II in rainbow trout ( Oncorhynchus mykiss ) myocytes in culture and the role of IGF-II in the PI3K/Akt and MAPK signalling pathways

Expression of mRNA Encoding IGF-I, IGF-II, Type-I, and II IGF-Receptors and IGF-Binding Proteins-1-4 during Ovarian Follicular Development in Buffalo (Bubalus bubalis)

Suppression of IGF‐I signals in neural stem cells enhances neurogenesis and olfactory function during aging

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