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How Does Mg 2+ (aq) Interact with ATP (aq) ? Biomolecular Structure through the Lens of Liquid-Jet Photoemission Spectroscopy

Journal of the American Chemical Society, 2024-06, Vol.146 (23), p.16062

2024

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2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6275), p.871-875

2016

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Real-time imaging of DNA loop extrusion by condensin

Science (American Association for the Advancement of Science), 2018-04, Vol.360 (6384), p.102-105

2018

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Stairway to translocation: AAA+ motor structures reveal the mechanisms of ATP‐dependent substrate translocation

Protein science, 2020-02, Vol.29 (2), p.407-419

2020

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Structural mechanism of cytosolic DNA sensing by cGAS

Nature (London), 2013-06, Vol.498 (7454), p.332-337

2013

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Agonist-bound structure of the human P2Y12 receptor

Nature (London), 2014-05, Vol.509 (7498), p.119-122

2014

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Active coacervate droplets are protocells that grow and resist Ostwald ripening

Nature communications, 2021-06, Vol.12 (1), p.3819-3819, Article 3819

2021

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Structural insight into substrate and inhibitor discrimination by human P-glycoprotein

Science (American Association for the Advancement of Science), 2019-02, Vol.363 (6428), p.753-756

2019

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A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP

Nature communications, 2019-02, Vol.10 (1), p.711-13, Article 711

2019

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Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

Nature communications, 2019-03, Vol.10 (1), p.1155-1155, Article 1155

2019

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Structures of the calcium-activated, non-selective cation channel TRPM4

Nature (London), 2017-12, Vol.552 (7684), p.205-209

2017

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Dynamic Chemistry of DNA-Based Nanoassemblies in Living Cells

Accounts of chemical research, 2024-10, Vol.57 (19), p.2763-2774

2024

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Cryo-EM structures capture the transport cycle of the P4-ATPase flippase

Science (American Association for the Advancement of Science), 2019-09, Vol.365 (6458), p.1149-1155

2019

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Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome

Nature communications, 2018-04, Vol.9 (1), p.1360-12, Article 1360

2018

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The mechanism of eukaryotic CMG helicase activation

Nature (London), 2018-03, Vol.555 (7695), p.265-268

2018

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Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation

Science (American Association for the Advancement of Science), 2018-02, Vol.359 (6378), p.915-919

2018

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Light-driven dinitrogen reduction catalyzed by a CdS:nitrogenase MoFe protein biohybrid

Science (American Association for the Advancement of Science), 2016-04, Vol.352 (6284), p.448-450

2016

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Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase

Nature communications, 2021-08, Vol.12 (1), p.4848-11, Article 4848

2021

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Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors

Science (American Association for the Advancement of Science), 2019-05, Vol.364 (6441), p.689-692

2019

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mTOR kinase structure, mechanism and regulation

Nature (London), 2013-05, Vol.497 (7448), p.217-223

2013

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Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction

Science (American Association for the Advancement of Science), 2013-03, Vol.339 (6123), p.1080-1083

2013

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A dynamic supramolecular polymer with stimuli-responsive handedness for in situ probing of enzymatic ATP hydrolysis

Nature communications, 2014-12, Vol.5 (1), p.5793-5793, Article 5793

2014

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Atomic model for the membrane-embedded V O motor of a eukaryotic V-ATPase

Nature (London), 2016-11, Vol.539 (7627), p.118

2016

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Molecular structure of the ATP-bound, phosphorylated human CFTR

Proceedings of the National Academy of Sciences - PNAS, 2018-12, Vol.115 (50), p.12757-12762

2018

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Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (30), p.11025-11030

2014

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How Does Mg 2+ (aq) Interact with ATP (aq) ? Biomolecular Structure through the Lens of Liquid-Jet Photoemission Spectroscopy

2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

Real-time imaging of DNA loop extrusion by condensin

Stairway to translocation: AAA+ motor structures reveal the mechanisms of ATP‐dependent substrate translocation

Structural mechanism of cytosolic DNA sensing by cGAS

Agonist-bound structure of the human P2Y12 receptor

Active coacervate droplets are protocells that grow and resist Ostwald ripening

Structural insight into substrate and inhibitor discrimination by human P-glycoprotein

A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP

Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

Structures of the calcium-activated, non-selective cation channel TRPM4

Dynamic Chemistry of DNA-Based Nanoassemblies in Living Cells

Cryo-EM structures capture the transport cycle of the P4-ATPase flippase

Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome

The mechanism of eukaryotic CMG helicase activation

Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation

Light-driven dinitrogen reduction catalyzed by a CdS:nitrogenase MoFe protein biohybrid

Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase

Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors

mTOR kinase structure, mechanism and regulation

Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction

A dynamic supramolecular polymer with stimuli-responsive handedness for in situ probing of enzymatic ATP hydrolysis

Atomic model for the membrane-embedded V O motor of a eukaryotic V-ATPase

Molecular structure of the ATP-bound, phosphorylated human CFTR

Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter

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