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Active coacervate droplets are protocells that grow and resist Ostwald ripening

Nature communications, 2021-06, Vol.12 (1), p.3819-3819, Article 3819

2021

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2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

Science (American Association for the Advancement of Science), 2016-02, Vol.351 (6275), p.871-875

2016

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Real-time imaging of DNA loop extrusion by condensin

Science (American Association for the Advancement of Science), 2018-04, Vol.360 (6384), p.102-105

2018

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Agonist-bound structure of the human P2Y12 receptor

Nature (London), 2014-05, Vol.509 (7498), p.119-122

2014

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Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

Nature communications, 2019-03, Vol.10 (1), p.1155-1155, Article 1155

2019

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Stairway to translocation: AAA+ motor structures reveal the mechanisms of ATP‐dependent substrate translocation

Protein science, 2020-02, Vol.29 (2), p.407-419

2020

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Structural mechanism of cytosolic DNA sensing by cGAS

Nature (London), 2013-06, Vol.498 (7454), p.332-337

2013

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A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP

Nature communications, 2019-02, Vol.10 (1), p.711-13, Article 711

2019

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Structural insight into substrate and inhibitor discrimination by human P-glycoprotein

Science (American Association for the Advancement of Science), 2019-02, Vol.363 (6428), p.753-756

2019

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Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome

Nature communications, 2018-04, Vol.9 (1), p.1360-12, Article 1360

2018

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The mechanism of eukaryotic CMG helicase activation

Nature (London), 2018-03, Vol.555 (7695), p.265-268

2018

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Structures of the calcium-activated, non-selective cation channel TRPM4

Nature (London), 2017-12, Vol.552 (7684), p.205-209

2017

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Cryo-EM structures capture the transport cycle of the P4-ATPase flippase

Science (American Association for the Advancement of Science), 2019-09, Vol.365 (6458), p.1149-1155

2019

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Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation

Science (American Association for the Advancement of Science), 2018-02, Vol.359 (6378), p.915-919

2018

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Light-driven dinitrogen reduction catalyzed by a CdS:nitrogenase MoFe protein biohybrid

Science (American Association for the Advancement of Science), 2016-04, Vol.352 (6284), p.448-450

2016

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Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase

Nature communications, 2021-08, Vol.12 (1), p.4848-11, Article 4848

2021

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In situ enzymatic control of colloidal phoresis and catalysis through hydrolysis of ATP

Nature communications, 2024-04, Vol.15 (1), p.3603-3603, Article 3603

2024

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Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors

Science (American Association for the Advancement of Science), 2019-05, Vol.364 (6441), p.689-692

2019

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mTOR kinase structure, mechanism and regulation

Nature (London), 2013-05, Vol.497 (7448), p.217-223

2013

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Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction

Science (American Association for the Advancement of Science), 2013-03, Vol.339 (6123), p.1080-1083

2013

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Molecular mechanism of ATP binding and ion channel activation in P2X receptors

Nature (London), 2012-05, Vol.485 (7397), p.207-212

2012

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A synthetic DNA motor that transports nanoparticles along carbon nanotubes

Nature nanotechnology, 2014-01, Vol.9 (1), p.39-43

2014

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Structural basis of AMPK regulation by small molecule activators

Nature communications, 2013-12, Vol.4 (1), p.3017-3017, Article 3017

2013

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Atomic model for the membrane-embedded V O motor of a eukaryotic V-ATPase

Nature (London), 2016-11, Vol.539 (7627), p.118

2016

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Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin

Nature communications, 2020-04, Vol.11 (1), p.1916-1916, Article 1916

2020

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Active coacervate droplets are protocells that grow and resist Ostwald ripening

2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition

Real-time imaging of DNA loop extrusion by condensin

Agonist-bound structure of the human P2Y12 receptor

Proteome-wide solubility and thermal stability profiling reveals distinct regulatory roles for ATP

Stairway to translocation: AAA+ motor structures reveal the mechanisms of ATP‐dependent substrate translocation

Structural mechanism of cytosolic DNA sensing by cGAS

A genetically encoded single-wavelength sensor for imaging cytosolic and cell surface ATP

Structural insight into substrate and inhibitor discrimination by human P-glycoprotein

Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome

The mechanism of eukaryotic CMG helicase activation

Structures of the calcium-activated, non-selective cation channel TRPM4

Cryo-EM structures capture the transport cycle of the P4-ATPase flippase

Molecular structure of human P-glycoprotein in the ATP-bound, outward-facing conformation

Light-driven dinitrogen reduction catalyzed by a CdS:nitrogenase MoFe protein biohybrid

Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase

In situ enzymatic control of colloidal phoresis and catalysis through hydrolysis of ATP

Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors

mTOR kinase structure, mechanism and regulation

Unraveling the Mechanism of Protein Disaggregation Through a ClpB-DnaK Interaction

Molecular mechanism of ATP binding and ion channel activation in P2X receptors

A synthetic DNA motor that transports nanoparticles along carbon nanotubes

Structural basis of AMPK regulation by small molecule activators

Atomic model for the membrane-embedded V O motor of a eukaryotic V-ATPase

Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin

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