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Insulin effects on CYP2E1, 2B, 3A, and 4A expression in primary cultured rat hepatocytes

Chemico-biological interactions, 1997-11, Vol.107 (1), p.75-91

1997

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Pig hepatocytes as an in vitro model to study the regulation of human CYP3A4: prediction of drug-drug interactions with 17α-ethynylestradiol

Chemico-biological interactions, 1997-11, Vol.107 (1), p.93-108

1997

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Hepatoprotective mechanism of silymarin: No evidence for involvement of cytochrome P450 2E1

Chemico-biological interactions, 1994-04, Vol.91 (1), p.51-63

1994

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Metabolism and biochemical effects of 3,3′,4,4′-tetrachlorobiphenyl in pregnant and fetal rats

Chemico-biological interactions, 1995-03, Vol.95 (1), p.41-56

1995

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Inhibition of cytochrome P450 enzymes and uridine 5′-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions

Chemico-biological interactions, 2022-01, Vol.352, p.109775-109775, Article 109775

2022

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Liver accumulation of 2,3,7,8-tetrachloro-[ 3H]dibenzofuran in mice: modulation by treatments with polychlorinated biphenyls

Chemico-biological interactions, 1993-12, Vol.89 (2), p.89-102

1993

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Effect of tetrahydrocurcumin on the profiles of drug-metabolizing enzymes induced by a high fat and high fructose diet in mice

Chemico-biological interactions, 2015-09, Vol.239, p.67-75

2015

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Enantioselective inhibition of Cytochrome P450-mediated drug metabolism by a novel antithrombotic agent, S002-333: Major effect on CYP2B6

Chemico-biological interactions, 2016-08, Vol.256, p.257-265

2016

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Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity

Chemico-biological interactions, 2016-08, Vol.255 (C), p.63-73

2016

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The immature rat as a potential model for chemical risks to children: Ontogeny of selected hepatic P450s

Chemico-biological interactions, 2016-08, Vol.256, p.167-177

2016

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Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo

Chemico-biological interactions, 2015-02, Vol.227, p.63-68

2015

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The human hepatoma HepaRG cells: A highly differentiated model for studies of liver metabolism and toxicity of xenobiotics

Chemico-biological interactions, 2007-05, Vol.168 (1), p.66-73

2007

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Synergistic increases of metabolism and oxidation–reduction genes on their expression after combined treatment with a CYP1A inducer and andrographolide

Chemico-biological interactions, 2009-12, Vol.182 (2), p.233-238

2009

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Cytochrome P450 expression and metabolic activation of cooked food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) in MCF10A breast epithelial cells

Chemico-biological interactions, 2006-04, Vol.160 (3), p.204-216

2006

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In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries

Chemico-biological interactions, 2016-08, Vol.255, p.12-22

2016

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Cytochrome P450 2E1 is the primary enzyme responsible for low-dose carbon tetrachloride metabolism in human liver microsomes

Chemico-biological interactions, 2000-03, Vol.125 (3), p.233-243

2000

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In vitro and in vivo metabolic activation of rhein and characterization of glutathione conjugates derived from rhein

Chemico-biological interactions, 2018-03, Vol.283, p.1-9

2018

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Involvement of P-glycoprotein and CYP 3A4 in the enhancement of etoposide bioavailability by a piperine analogue

Chemico-biological interactions, 2011-04, Vol.190 (2), p.84-90

2011

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Fipronil induces CYP isoforms and cytotoxicity in human hepatocytes

Chemico-biological interactions, 2006-12, Vol.164 (3), p.200-214

2006

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Definition of metabolism-dependent xenobiotic toxicity with co-cultures of human hepatocytes and mouse 3T3 fibroblasts in the novel integrated discrete multiple organ co-culture (IdMOC) experimental system: Results with model toxicants aflatoxin B1, cyclophosphamide and tamoxifen

Chemico-biological interactions, 2012-07, Vol.199 (1), p.1-8

2012

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Risk assessment and mitigation strategies for reactive metabolites in drug discovery and development

Chemico-biological interactions, 2011-06, Vol.192 (1), p.65-71

2011

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Asiatic acid abridges pre-neoplastic lesions, inflammation, cell proliferation and induces apoptosis in a rat model of colon carcinogenesis

Chemico-biological interactions, 2017-12, Vol.278, p.197-211

2017

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Human hepatocytes: Isolation, cryopreservation and applications in drug development

Chemico-biological interactions, 2007-05, Vol.168 (1), p.16-29

Li, Albert P.

2007

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Effects of CYP inhibitors on precocene I metabolism and toxicity in rat liver slices

Chemico-biological interactions, 2011-09, Vol.193 (2), p.109-118

2011

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Maneb and paraquat-induced modulation of toxicant responsive genes in the rat liver: Comparison with polymorphonuclear leukocytes

Chemico-biological interactions, 2010-12, Vol.188 (3), p.566-579

2010

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Insulin effects on CYP2E1, 2B, 3A, and 4A expression in primary cultured rat hepatocytes

Pig hepatocytes as an in vitro model to study the regulation of human CYP3A4: prediction of drug-drug interactions with 17α-ethynylestradiol

Hepatoprotective mechanism of silymarin: No evidence for involvement of cytochrome P450 2E1

Metabolism and biochemical effects of 3,3′,4,4′-tetrachlorobiphenyl in pregnant and fetal rats

Inhibition of cytochrome P450 enzymes and uridine 5′-diphospho-glucuronosyltransferases by vicagrel in human liver microsomes: A prediction of potential drug-drug interactions

Liver accumulation of 2,3,7,8-tetrachloro-[ 3H]dibenzofuran in mice: modulation by treatments with polychlorinated biphenyls

Effect of tetrahydrocurcumin on the profiles of drug-metabolizing enzymes induced by a high fat and high fructose diet in mice

Enantioselective inhibition of Cytochrome P450-mediated drug metabolism by a novel antithrombotic agent, S002-333: Major effect on CYP2B6

Development of HepG2-derived cells expressing cytochrome P450s for assessing metabolism-associated drug-induced liver toxicity

The immature rat as a potential model for chemical risks to children: Ontogeny of selected hepatic P450s

Monepantel induces hepatic cytochromes p450 in sheep in vitro and in vivo

The human hepatoma HepaRG cells: A highly differentiated model for studies of liver metabolism and toxicity of xenobiotics

Synergistic increases of metabolism and oxidation–reduction genes on their expression after combined treatment with a CYP1A inducer and andrographolide

Cytochrome P450 expression and metabolic activation of cooked food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine (PhIP) in MCF10A breast epithelial cells

In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries

Cytochrome P450 2E1 is the primary enzyme responsible for low-dose carbon tetrachloride metabolism in human liver microsomes

In vitro and in vivo metabolic activation of rhein and characterization of glutathione conjugates derived from rhein

Involvement of P-glycoprotein and CYP 3A4 in the enhancement of etoposide bioavailability by a piperine analogue

Fipronil induces CYP isoforms and cytotoxicity in human hepatocytes

Definition of metabolism-dependent xenobiotic toxicity with co-cultures of human hepatocytes and mouse 3T3 fibroblasts in the novel integrated discrete multiple organ co-culture (IdMOC) experimental system: Results with model toxicants aflatoxin B1, cyclophosphamide and tamoxifen

Risk assessment and mitigation strategies for reactive metabolites in drug discovery and development

Asiatic acid abridges pre-neoplastic lesions, inflammation, cell proliferation and induces apoptosis in a rat model of colon carcinogenesis

Human hepatocytes: Isolation, cryopreservation and applications in drug development

Effects of CYP inhibitors on precocene I metabolism and toxicity in rat liver slices

Maneb and paraquat-induced modulation of toxicant responsive genes in the rat liver: Comparison with polymorphonuclear leukocytes

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