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Mechanism-based inactivation of cytochrome P-450-3A4 by mifepristone (RU486)

The Journal of pharmacology and experimental therapeutics, 1999-02, Vol.288 (2), p.791

1999

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Effects of chronic ethanol on growth hormone secretion and hepatic cytochrome P450 isozymes of the rat

The Journal of pharmacology and experimental therapeutics, 1993-01, Vol.264 (1), p.438

1993

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Investigation of aortic CYP3A bioactivation of nitroglycerin in vivo

The Journal of pharmacology and experimental therapeutics, 1997-06, Vol.281 (3), p.1499

1997

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Characterization of pyrazole and 4-methylpyrazole induction of cytochrome P4502E1 in rat kidney

The Journal of pharmacology and experimental therapeutics, 1994-07, Vol.270 (1), p.407

1994

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Comparative pharmacodynamics of hepatic cytochrome P450 2B induction by 5,5-diphenyl- and 5,5-diethyl-substituted barbiturates and hydantoins in the male F344/NCr rat

The Journal of pharmacology and experimental therapeutics, 1994-07, Vol.270 (1), p.348

1994

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Phencyclidine continuous dosing produces a treatment time-dependent regulation of rat CYP2C11 function, protein expression and mRNA levels

The Journal of pharmacology and experimental therapeutics, 1997-04, Vol.281 (1), p.574

1997

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Mechanism-based inactivation of cytochrome P450 1A1 by N-aralkyl-1-aminobenzotriazoles in guinea pig kidney in vivo and in vitro: minimal effects on metabolism of arachidonic acid by renal P450-dependent monooxygenases

The Journal of pharmacology and experimental therapeutics, 1993-11, Vol.267 (2), p.758

1993

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Suppressed expression of phenobarbital-inducible hepatic cytochrome P-450s in Eisai-hyperbilirubinuria rats (EHBR/Eis)

The Journal of pharmacology and experimental therapeutics, 1996-06, Vol.277 (3), p.1676

1996

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Interleukin-1 beta differentially represses drug-metabolizing enzymes in arthritic female rats

The Journal of pharmacology and experimental therapeutics, 1993-02, Vol.264 (2), p.1012

1993

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Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers

The Journal of pharmacology and experimental therapeutics, 2007-01, Vol.320 (1), p.72

2007

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20-Hydroxyeicosatetraenoic acid inhibition attenuates balloon injury-induced neointima formation and vascular remodeling in rat carotid arteries

The Journal of pharmacology and experimental therapeutics, 2013-07, Vol.346 (1), p.67

2013

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Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo

The Journal of pharmacology and experimental therapeutics, 2009-06, Vol.329 (3), p.908

2009

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Role of intestinal cytochrome p450 enzymes in diclofenac-induced toxicity in the small intestine

The Journal of pharmacology and experimental therapeutics, 2012-11, Vol.343 (2), p.362

2012

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Overexpression of cytochrome P450 epoxygenases prevents development of hypertension in spontaneously hypertensive rats by enhancing atrial natriuretic peptide

The Journal of pharmacology and experimental therapeutics, 2010-09, Vol.334 (3), p.784

2010

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Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites

The Journal of pharmacology and experimental therapeutics, 2002-02, Vol.300 (2), p.549

2002

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Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation

The Journal of pharmacology and experimental therapeutics, 2003-01, Vol.304 (1), p.223

2003

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Generation and characterization of a Cyp2f2-null mouse and studies on the role of CYP2F2 in naphthalene-induced toxicity in the lung and nasal olfactory mucosa

The Journal of pharmacology and experimental therapeutics, 2011-10, Vol.339 (1), p.62

2011

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The grapefruit juice effect is not limited to cytochrome P450 (P450) 3A4: evidence for bergamottin-dependent inactivation, heme destruction, and covalent binding to protein in P450s 2B6 and 3A5

The Journal of pharmacology and experimental therapeutics, 2005-04, Vol.313 (1), p.154

2005

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Rifaximin is a gut-specific human pregnane X receptor activator

The Journal of pharmacology and experimental therapeutics, 2007-07, Vol.322 (1), p.391

2007

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Growth hormone determines sexual dimorphism of hepatic cytochrome P450 3A4 expression in transgenic mice

The Journal of pharmacology and experimental therapeutics, 2006-03, Vol.316 (3), p.1328

2006

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Functional Interaction between Pregnane X Receptor and Yes-Associated Protein in Xenobiotic-Dependent Liver Hypertrophy and Drug Metabolism

The Journal of pharmacology and experimental therapeutics, 2019-12, Vol.371 (3), p.590

2019

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5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent

The Journal of pharmacology and experimental therapeutics, 2011-12, Vol.339 (3), p.886

2011

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Impaired microsomal oxidation of the atypical antipsychotic agent clozapine in hepatic steatosis

The Journal of pharmacology and experimental therapeutics, 2007-08, Vol.322 (2), p.770

2007

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Nitric oxide and interleukin-1β stimulate the proteasome-independent degradation of the retinoic acid hydroxylase CYP2C22 in primary rat hepatocytes

The Journal of pharmacology and experimental therapeutics, 2014-01, Vol.348 (1), p.141

2014

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Catalytic activity and isoform-specific inhibition of rat cytochrome p450 4F enzymes

The Journal of pharmacology and experimental therapeutics, 2004-03, Vol.308 (3), p.887

2004

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Mechanism-based inactivation of cytochrome P-450-3A4 by mifepristone (RU486)

Effects of chronic ethanol on growth hormone secretion and hepatic cytochrome P450 isozymes of the rat

Investigation of aortic CYP3A bioactivation of nitroglycerin in vivo

Characterization of pyrazole and 4-methylpyrazole induction of cytochrome P4502E1 in rat kidney

Comparative pharmacodynamics of hepatic cytochrome P450 2B induction by 5,5-diphenyl- and 5,5-diethyl-substituted barbiturates and hydantoins in the male F344/NCr rat

Phencyclidine continuous dosing produces a treatment time-dependent regulation of rat CYP2C11 function, protein expression and mRNA levels

Mechanism-based inactivation of cytochrome P450 1A1 by N-aralkyl-1-aminobenzotriazoles in guinea pig kidney in vivo and in vitro: minimal effects on metabolism of arachidonic acid by renal P450-dependent monooxygenases

Suppressed expression of phenobarbital-inducible hepatic cytochrome P-450s in Eisai-hyperbilirubinuria rats (EHBR/Eis)

Interleukin-1 beta differentially represses drug-metabolizing enzymes in arthritic female rats

Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers

20-Hydroxyeicosatetraenoic acid inhibition attenuates balloon injury-induced neointima formation and vascular remodeling in rat carotid arteries

Selective inhibitors of CYP2J2 related to terfenadine exhibit strong activity against human cancers in vitro and in vivo

Role of intestinal cytochrome p450 enzymes in diclofenac-induced toxicity in the small intestine

Overexpression of cytochrome P450 epoxygenases prevents development of hypertension in spontaneously hypertensive rats by enhancing atrial natriuretic peptide

Effect of 17-alpha-ethynylestradiol on activities of cytochrome P450 2B (P450 2B) enzymes: characterization of inactivation of P450s 2B1 and 2B6 and identification of metabolites

Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation

Generation and characterization of a Cyp2f2-null mouse and studies on the role of CYP2F2 in naphthalene-induced toxicity in the lung and nasal olfactory mucosa

The grapefruit juice effect is not limited to cytochrome P450 (P450) 3A4: evidence for bergamottin-dependent inactivation, heme destruction, and covalent binding to protein in P450s 2B6 and 3A5

Rifaximin is a gut-specific human pregnane X receptor activator

Growth hormone determines sexual dimorphism of hepatic cytochrome P450 3A4 expression in transgenic mice

Functional Interaction between Pregnane X Receptor and Yes-Associated Protein in Xenobiotic-Dependent Liver Hypertrophy and Drug Metabolism

5-Aminoimidazole-4-carboxyamide-ribonucleoside (AICAR)-stimulated hepatic expression of Cyp4a10, Cyp4a14, Cyp4a31, and other peroxisome proliferator-activated receptor α-responsive mouse genes is AICAR 5'-monophosphate-dependent and AMP-activated protein kinase-independent

Impaired microsomal oxidation of the atypical antipsychotic agent clozapine in hepatic steatosis

Nitric oxide and interleukin-1β stimulate the proteasome-independent degradation of the retinoic acid hydroxylase CYP2C22 in primary rat hepatocytes

Catalytic activity and isoform-specific inhibition of rat cytochrome p450 4F enzymes

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