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Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities

The Journal of pharmacology and experimental therapeutics, 1999-08, Vol.290 (2), p.854

1999

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In vivo CYP3A4 heteroactivation is a possible mechanism for the drug interaction between felbamate and carbamazepine

The Journal of pharmacology and experimental therapeutics, 2003-06, Vol.305 (3), p.1251-1262

2003

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Involvement of human CYP1A isoenzymes in the metabolism and drug interactions of riluzole in vitro

The Journal of pharmacology and experimental therapeutics, 1997-09, Vol.282 (3), p.1465

1997

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Oncostatin M down-regulates basal and induced cytochromes P450 in human hepatocytes

The Journal of pharmacology and experimental therapeutics, 1998-04, Vol.285 (1), p.127

1998

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Effects of chronic ethanol on growth hormone secretion and hepatic cytochrome P450 isozymes of the rat

The Journal of pharmacology and experimental therapeutics, 1993-01, Vol.264 (1), p.438

1993

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Investigation of aortic CYP3A bioactivation of nitroglycerin in vivo

The Journal of pharmacology and experimental therapeutics, 1997-06, Vol.281 (3), p.1499

1997

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Characterization of pyrazole and 4-methylpyrazole induction of cytochrome P4502E1 in rat kidney

The Journal of pharmacology and experimental therapeutics, 1994-07, Vol.270 (1), p.407

1994

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Comparative pharmacodynamics of hepatic cytochrome P450 2B induction by 5,5-diphenyl- and 5,5-diethyl-substituted barbiturates and hydantoins in the male F344/NCr rat

The Journal of pharmacology and experimental therapeutics, 1994-07, Vol.270 (1), p.348

1994

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Phencyclidine continuous dosing produces a treatment time-dependent regulation of rat CYP2C11 function, protein expression and mRNA levels

The Journal of pharmacology and experimental therapeutics, 1997-04, Vol.281 (1), p.574

1997

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Suppressed expression of phenobarbital-inducible hepatic cytochrome P-450s in Eisai-hyperbilirubinuria rats (EHBR/Eis)

The Journal of pharmacology and experimental therapeutics, 1996-06, Vol.277 (3), p.1676

1996

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Interleukin-1 beta differentially represses drug-metabolizing enzymes in arthritic female rats

The Journal of pharmacology and experimental therapeutics, 1993-02, Vol.264 (2), p.1012

1993

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Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers

The Journal of pharmacology and experimental therapeutics, 2007-01, Vol.320 (1), p.72-80

2007

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Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil

The Journal of pharmacology and experimental therapeutics, 2004-10, Vol.311 (1), p.228-236

2004

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Hydrocodone, Oxycodone, and Morphine Metabolism and Drug-Drug Interactions

The Journal of pharmacology and experimental therapeutics, 2023-11, Vol.387 (2), p.150-169

2023

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Overexpression of cytochrome P450 epoxygenases prevents development of hypertension in spontaneously hypertensive rats by enhancing atrial natriuretic peptide

The Journal of pharmacology and experimental therapeutics, 2010-09, Vol.334 (3), p.784-794

2010

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Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor

The Journal of pharmacology and experimental therapeutics, 2006-06, Vol.317 (3), p.1200-1209

2006

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Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation

The Journal of pharmacology and experimental therapeutics, 2003-01, Vol.304 (1), p.223-228

2003

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Identification of the human cytochromes p450 responsible for in vitro formation of R- and S-norfluoxetine

The Journal of pharmacology and experimental therapeutics, 2001-06, Vol.297 (3), p.1044

2001

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CYP3A4 substrate selection and substitution in the prediction of potential drug-drug interactions

The Journal of pharmacology and experimental therapeutics, 2005-07, Vol.314 (1), p.180-190

2005

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Estimation of drug-metabolizing capacity by cytochrome P450 genotyping and expression

The Journal of pharmacology and experimental therapeutics, 2012-04, Vol.341 (1), p.294-305

2012

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Dissecting the activation of thienopyridines by cytochromes P450 using a pharmacodynamic assay in vitro

The Journal of pharmacology and experimental therapeutics, 2011-11, Vol.339 (2), p.589-596

2011

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Generation and characterization of a Cyp2f2-null mouse and studies on the role of CYP2F2 in naphthalene-induced toxicity in the lung and nasal olfactory mucosa

The Journal of pharmacology and experimental therapeutics, 2011-10, Vol.339 (1), p.62-71

2011

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Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral Neuropathy

The Journal of pharmacology and experimental therapeutics, 2016-11, Vol.359 (2), p.300-309

2016

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Rifaximin is a gut-specific human pregnane X receptor activator

The Journal of pharmacology and experimental therapeutics, 2007-07, Vol.322 (1), p.391-398

2007

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Growth hormone determines sexual dimorphism of hepatic cytochrome P450 3A4 expression in transgenic mice

The Journal of pharmacology and experimental therapeutics, 2006-03, Vol.316 (3), p.1328-1334

2006

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Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities

In vivo CYP3A4 heteroactivation is a possible mechanism for the drug interaction between felbamate and carbamazepine

Involvement of human CYP1A isoenzymes in the metabolism and drug interactions of riluzole in vitro

Oncostatin M down-regulates basal and induced cytochromes P450 in human hepatocytes

Effects of chronic ethanol on growth hormone secretion and hepatic cytochrome P450 isozymes of the rat

Investigation of aortic CYP3A bioactivation of nitroglycerin in vivo

Characterization of pyrazole and 4-methylpyrazole induction of cytochrome P4502E1 in rat kidney

Comparative pharmacodynamics of hepatic cytochrome P450 2B induction by 5,5-diphenyl- and 5,5-diethyl-substituted barbiturates and hydantoins in the male F344/NCr rat

Phencyclidine continuous dosing produces a treatment time-dependent regulation of rat CYP2C11 function, protein expression and mRNA levels

Suppressed expression of phenobarbital-inducible hepatic cytochrome P-450s in Eisai-hyperbilirubinuria rats (EHBR/Eis)

Interleukin-1 beta differentially represses drug-metabolizing enzymes in arthritic female rats

Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers

Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug interaction between cerivastatin and gemfibrozil

Hydrocodone, Oxycodone, and Morphine Metabolism and Drug-Drug Interactions

Overexpression of cytochrome P450 epoxygenases prevents development of hypertension in spontaneously hypertensive rats by enhancing atrial natriuretic peptide

Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor

Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation

Identification of the human cytochromes p450 responsible for in vitro formation of R- and S-norfluoxetine

CYP3A4 substrate selection and substitution in the prediction of potential drug-drug interactions

Estimation of drug-metabolizing capacity by cytochrome P450 genotyping and expression

Dissecting the activation of thienopyridines by cytochromes P450 using a pharmacodynamic assay in vitro

Generation and characterization of a Cyp2f2-null mouse and studies on the role of CYP2F2 in naphthalene-induced toxicity in the lung and nasal olfactory mucosa

Identification and Characterization of New Chemical Entities Targeting Apurinic/Apyrimidinic Endonuclease 1 for the Prevention of Chemotherapy-Induced Peripheral Neuropathy

Rifaximin is a gut-specific human pregnane X receptor activator

Growth hormone determines sexual dimorphism of hepatic cytochrome P450 3A4 expression in transgenic mice

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