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The superfamily of heptahelical receptors

Nature cell biology, 2000-07, Vol.2 (7), p.E133-E136

Lefkowitz, Robert J

2000

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Expanding roles for β-arrestins as scaffolds and adapters in GPCR signaling and trafficking

Current Opinion in Cell Biology, 2001-04, Vol.13 (2), p.139-145

2001

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Relative Opioid Efficacy Is Determined by the Complements of the G Protein-Coupled Receptor Desensitization Machinery

Molecular pharmacology, 2004-07, Vol.66 (1), p.106-112

2004

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Functional consequences of altering myocardial adrenergic receptor signaling

Annual review of physiology, 2000-01, Vol.62 (1), p.237-260

2000

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Role of Endocytosis in the Activation of the Extracellular Signal-Regulated Kinase Cascade by Sequestering and Nonsequestering G Protein-Coupled Receptors

Proceedings of the National Academy of Sciences - PNAS, 2000-02, Vol.97 (4), p.1489-1494

2000

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Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy

The Journal of clinical investigation, 2001-04, Vol.107 (8), p.967-974

2001

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Platelet-Derived Growth Factor Receptor Association with Na+/H+ Exchanger Regulatory Factor Potentiates Receptor Activity

Molecular and Cellular Biology, 2000-11, Vol.20 (22), p.8352-8363

2000

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G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization

The Journal of biological chemistry, 1998-07, Vol.273 (30), p.18677-18680

Lefkowitz, R J

1998

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G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation

American journal of physiology. Lung cellular and molecular physiology, 2004-02, Vol.286 (2), p.312-L319

2004

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Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases

The Journal of biological chemistry, 1999-05, Vol.274 (20), p.13978-13984

1999

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Independent β-Arrestin 2 and G Protein-Mediated Pathways for Angiotensin II Activation of Extracellular Signal-Regulated Kinases 1 and 2

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (19), p.10782-10787

2003

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Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

Neuron (Cambridge, Mass.), 1999-12, Vol.24 (4), p.1029-1036

1999

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Binding of G protein beta gamma-subunits to pleckstrin homology domains

The Journal of biological chemistry, 1994-04, Vol.269 (14), p.10217-10220

1994

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Classical and new roles of β-arrestins in the regulation of G-PROTEIN-COUPLED receptors

Nature reviews. Neuroscience, 2001-10, Vol.2 (10), p.727-733

2001

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The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase

The Journal of biological chemistry, 1993-04, Vol.268 (11), p.8256-8260

1993

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Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins

Progress in neurobiology, 2002-02, Vol.66 (2), p.61-79

2002

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β-Arrestin Inhibits NF-κB Activity by Means of Its Interaction with the NF-κB Inhibitor IκBα

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (23), p.8603-8607

2004

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Adrenergic receptors. Models for the study of receptors coupled to guanine nucleotide regulatory proteins

The Journal of biological chemistry, 1988-04, Vol.263 (11), p.4993-4996

1988

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Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation

The Journal of biological chemistry, 1992-01, Vol.267 (3), p.1430-1433

1992

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Differential Mechanisms of Morphine Antinociceptive Tolerance Revealed in beta Arrestin-2 Knock-Out Mice

The Journal of neuroscience, 2002-12, Vol.22 (23), p.10494-10500

2002

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G PROTEIN-COUPLED RECEPTOR KINASES

Annual review of biochemistry, 1998-01, Vol.67 (1), p.653-692

1998

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New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades

Oncogene, 2001-03, Vol.20 (13), p.1532-1539

2001

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Reciprocal Regulation of Angiotensin Receptor-activated Extracellular Signal-regulated Kinases by β-Arrestins 1 and 2

The Journal of biological chemistry, 2004-02, Vol.279 (9), p.7807-7811

2004

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Regulation of tyrosine kinase cascades by G-protein-coupled receptors

Current opinion in cell biology, 1999-04, Vol.11 (2), p.177-183

1999

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Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C

Molecular pharmacology, 1995-08, Vol.48 (2), p.173-177

1995

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The superfamily of heptahelical receptors

Expanding roles for β-arrestins as scaffolds and adapters in GPCR signaling and trafficking

Relative Opioid Efficacy Is Determined by the Complements of the G Protein-Coupled Receptor Desensitization Machinery

Functional consequences of altering myocardial adrenergic receptor signaling

Role of Endocytosis in the Activation of the Extracellular Signal-Regulated Kinase Cascade by Sequestering and Nonsequestering G Protein-Coupled Receptors

Alterations in cardiac adrenergic signaling and calcium cycling differentially affect the progression of cardiomyopathy

Platelet-Derived Growth Factor Receptor Association with Na+/H+ Exchanger Regulatory Factor Potentiates Receptor Activity

G protein-coupled receptors. III. New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization

G protein-coupled receptor kinase 5 regulates airway responses induced by muscarinic receptor activation

Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases

Independent β-Arrestin 2 and G Protein-Mediated Pathways for Angiotensin II Activation of Extracellular Signal-Regulated Kinases 1 and 2

Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

Binding of G protein beta gamma-subunits to pleckstrin homology domains

Classical and new roles of β-arrestins in the regulation of G-PROTEIN-COUPLED receptors

The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase

Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins

β-Arrestin Inhibits NF-κB Activity by Means of Its Interaction with the NF-κB Inhibitor IκBα

Adrenergic receptors. Models for the study of receptors coupled to guanine nucleotide regulatory proteins

Constitutive activation of the alpha 1B-adrenergic receptor by all amino acid substitutions at a single site. Evidence for a region which constrains receptor activation

Differential Mechanisms of Morphine Antinociceptive Tolerance Revealed in beta Arrestin-2 Knock-Out Mice

G PROTEIN-COUPLED RECEPTOR KINASES

New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades

Reciprocal Regulation of Angiotensin Receptor-activated Extracellular Signal-regulated Kinases by β-Arrestins 1 and 2

Regulation of tyrosine kinase cascades by G-protein-coupled receptors

Agonist-dependent phosphorylation of the mouse delta-opioid receptor: involvement of G protein-coupled receptor kinases but not protein kinase C

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