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Progress of ATM inhibitors: Opportunities and challenges

European journal of medicinal chemistry, 2024-11, Vol.277, p.116781, Article 116781

2024

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Emerging pharmacological approaches for Huntington's disease

European journal of pharmacology, 2024-10, Vol.980, p.176873, Article 176873

2024

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Emerging roles of cannabinoid receptor CB2 receptor in the central nervous system: therapeutic target for CNS disorders

Psychopharmacology, 2024-10, Vol.241 (10), p.1939-1954

2024

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Parthenolide ameliorates 3-nitropropionic acid-induced Huntington's disease-like aberrations via modulating NLRP3 inflammasome, reducing microglial activation and inducing astrocyte shifting

Molecular medicine (Cambridge, Mass.), 2024-09, Vol.30 (1), p.158-21, Article 158

2024

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Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntington's disease

Proceedings of the National Academy of Sciences - PNAS, 2024-09, Vol.121 (39), p.e2406308121

2024

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Epigenetic Orchestration of Neurodegenerative Disorders: A Possible Target for Curcumin as a Therapeutic

Neurochemical research, 2024-09, Vol.49 (9), p.2319-2335

2024

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Luteolin as potential treatment for Huntington's disease: Insights from a transgenic mouse model

CNS neuroscience & therapeutics, 2024-09, Vol.30 (9), p.e70025-n/a

2024

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Flavonoids as Potential Therapeutics Against Neurodegenerative Disorders: Unlocking the Prospects

Neurochemical research, 2024-08, Vol.49 (8), p.1926-1944

2024

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Mitochondrial targeted antioxidants as potential therapy for huntington’s disease

Pharmacological reports, 2024-08, Vol.76 (4), p.693-713

2024

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Neuroprotective effects of levothyroxine on cognition deficits and memory in an experimental model of Huntingtonʼs disease in rats: An electrophysiological study

Naunyn-Schmiedeberg's archives of pharmacology, 2024-08, Vol.397 (8), p.5939-5951

2024

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Effect of Capsaicin on 3-NP-Induced Neurotoxicity: A Pre-Clinical Study

Neurochemical research, 2024-08, Vol.49 (8), p.2038-2059

2024

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6-shogaol against 3-Nitropropionic acid-induced Huntington's disease in rodents: Based on molecular docking/targeting pro-inflammatory cytokines/NF-κB-BDNF-Nrf2 pathway

PloS one, 2024-07, Vol.19 (7), p.e0305358

2024

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Gastrodin Improves the Activity of the Ubiquitin-Proteasome System and the Autophagy-Lysosome Pathway to Degrade Mutant Huntingtin

International journal of molecular sciences, 2024-07, Vol.25 (14), p.7709

2024

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Emerging phosphodiesterase inhibitors for treatment of neurodegenerative diseases

Medicinal research reviews, 2024-07, Vol.44 (4), p.1404-1445

2024

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New insights into sodium phenylbutyrate as a pharmacotherapeutic option for neurological disorders

Synapse (New York, N.Y.), 2024-07, Vol.78 (4), p.e22301-n/a

2024

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Let's get fat: emergence of S-acylation as a therapeutic target in Huntington disease

Biochemical Society transactions, 2024-06, Vol.52 (3), p.1385-1392

2024

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Quercetin’s Restorative Properties in Male Mice with 3-Nitropropionic Acid-induced Huntington-like Symptoms: Molecular Docking, Behavioral, and Biochemical Assessment

Cell biochemistry and biophysics, 2024-06, Vol.82 (2), p.1489-1502

2024

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Potential Use of the Cholesterol Transfer Inhibitor U18666A as a Potent Research Tool for the Study of Cholesterol Mechanisms in Neurodegenerative Disorders

Molecular neurobiology, 2024-06, Vol.61 (6), p.3503-3527

2024

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3-Hydroxyanthranilic Acid Delays Paralysis in Caenorhabditis elegans Models of Amyloid-Beta and Polyglutamine Proteotoxicity

Biomolecules (Basel, Switzerland), 2024-05, Vol.14 (5), p.599

2024

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The Vital Role of Melatonin and Its Metabolites in the Neuroprotection and Retardation of Brain Aging

International journal of molecular sciences, 2024-05, Vol.25 (10), p.5122

2024

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Correction of symptoms of Huntington disease by genistein through FOXO3-mediated autophagy stimulation

Autophagy, 2024-05, Vol.20 (5), p.1159-1182

2024

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Agmatine mitigates behavioral abnormalities and neurochemical dysregulation associated with 3-Nitropropionic acid-induced Huntington's disease in rats

Neurotoxicology (Park Forest South), 2024-05, Vol.102, p.12-28

2024

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Multifunctional Nanocarriers for Alzheimer’s Disease: Befriending the Barriers

Molecular neurobiology, 2024-05, Vol.61 (5), p.3042-3089

2024

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Microglial cytokines poison neuronal autophagy via CCR5, a druggable target

Autophagy, 2024-04, Vol.20 (4), p.949-951

2024

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Large animal models for Huntington's disease research

Dōngwùxué yánjiū, 2024-03, Vol.45 (2), p.275-283

2024

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Progress of ATM inhibitors: Opportunities and challenges

Emerging pharmacological approaches for Huntington's disease

Emerging roles of cannabinoid receptor CB2 receptor in the central nervous system: therapeutic target for CNS disorders

Parthenolide ameliorates 3-nitropropionic acid-induced Huntington's disease-like aberrations via modulating NLRP3 inflammasome, reducing microglial activation and inducing astrocyte shifting

Fructose-2,6-bisphosphate restores DNA repair activity of PNKP and ameliorates neurodegenerative symptoms in Huntington's disease

Epigenetic Orchestration of Neurodegenerative Disorders: A Possible Target for Curcumin as a Therapeutic

Luteolin as potential treatment for Huntington's disease: Insights from a transgenic mouse model

Flavonoids as Potential Therapeutics Against Neurodegenerative Disorders: Unlocking the Prospects

Mitochondrial targeted antioxidants as potential therapy for huntington’s disease

Neuroprotective effects of levothyroxine on cognition deficits and memory in an experimental model of Huntingtonʼs disease in rats: An electrophysiological study

Effect of Capsaicin on 3-NP-Induced Neurotoxicity: A Pre-Clinical Study

6-shogaol against 3-Nitropropionic acid-induced Huntington's disease in rodents: Based on molecular docking/targeting pro-inflammatory cytokines/NF-κB-BDNF-Nrf2 pathway

Gastrodin Improves the Activity of the Ubiquitin-Proteasome System and the Autophagy-Lysosome Pathway to Degrade Mutant Huntingtin

Emerging phosphodiesterase inhibitors for treatment of neurodegenerative diseases

New insights into sodium phenylbutyrate as a pharmacotherapeutic option for neurological disorders

Let's get fat: emergence of S-acylation as a therapeutic target in Huntington disease

Quercetin’s Restorative Properties in Male Mice with 3-Nitropropionic Acid-induced Huntington-like Symptoms: Molecular Docking, Behavioral, and Biochemical Assessment

Potential Use of the Cholesterol Transfer Inhibitor U18666A as a Potent Research Tool for the Study of Cholesterol Mechanisms in Neurodegenerative Disorders

3-Hydroxyanthranilic Acid Delays Paralysis in Caenorhabditis elegans Models of Amyloid-Beta and Polyglutamine Proteotoxicity

The Vital Role of Melatonin and Its Metabolites in the Neuroprotection and Retardation of Brain Aging

Correction of symptoms of Huntington disease by genistein through FOXO3-mediated autophagy stimulation

Agmatine mitigates behavioral abnormalities and neurochemical dysregulation associated with 3-Nitropropionic acid-induced Huntington's disease in rats

Multifunctional Nanocarriers for Alzheimer’s Disease: Befriending the Barriers

Microglial cytokines poison neuronal autophagy via CCR5, a druggable target

Large animal models for Huntington's disease research

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