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Huntington's Disease Clinical Trials Corner: April 2020
Journal of Huntington's disease, 2020-01, Vol.9 (2), p.185-197
2020
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Sleep Dysfunction in Huntington's Disease: Impacts of Current Medications and Prospects for Treatment
Journal of Huntington's disease, 2023-01, Vol.12 (2), p.149-161
2023
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Effects of Pridopidine on Functional Capacity in Early-Stage Participants from the PRIDE-HD Study
Journal of Huntington's disease, 2020-01, Vol.9 (4), p.371-380
2020
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Effects of an Angiotensin IV Analog on 3-Nitropropionic Acid-Induced Huntington's Disease-Like Symptoms in Rats
Journal of Huntington's disease, 2024-01, Vol.13 (1), p.55-66
2024
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Fifteen Years of Clinical Trials in Huntington's Disease: A Very Low Clinical Drug Development Success Rate
Journal of Huntington's disease, 2017-01, Vol.6 (2), p.157-163
2017
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Huntington’s Disease Clinical Trials Corner: February 2018
Journal of Huntington's disease, 2018-01, Vol.7 (1), p.89-98
2018
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Additional Safety and Exploratory Efficacy Data at 48 and 60 Months from Open-HART, an Open-Label Extension Study of Pridopidine in Huntington Disease
Journal of Huntington's disease, 2020-01, Vol.9 (2), p.173-184
2020
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LBH589, A Hydroxamic Acid-Derived HDAC Inhibitor, is Neuroprotective in Mouse Models of Huntington's Disease
Journal of Huntington's disease, 2016-12, Vol.5 (4), p.347-355
2016
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Is Huntingtin Dispensable in the Adult Brain?
Journal of Huntington's disease, 2017-01, Vol.6 (1), p.1-17
2017
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A Double-Pronged Sword: XJB-5-131 Is a Suppressor of Somatic Instability and Toxicity in Huntington's Disease
Journal of Huntington's disease, 2022-01, Vol.11 (1), p.3-15
2022
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Targeting the Cholinergic System to Develop a Novel Therapy for Huntington's Disease
Journal of Huntington's disease, 2016-12, Vol.5 (4), p.333-342
2016
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Pridopidine: Overview of Pharmacology and Rationale for its Use in Huntington's Disease
Journal of Huntington's disease, 2018-01, Vol.7 (1), p.1-16
2018
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Indoleamine 2,3 Dioxygenase as a Potential Therapeutic Target in Huntington's Disease
Journal of Huntington's disease, 2015-07, Vol.4 (2), p.109
2015
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Disease-Modification in Huntington's Disease: Moving Away from a Single-Target Approach
Journal of Huntington's disease, 2019-01, Vol.8 (1), p.9-22
2019
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Epigenetic Mechanisms Involved in Huntington's Disease Pathogenesis
Journal of Huntington's disease, 2015, Vol.4 (1), p.1-15
2015
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PBT2 Reduces Toxicity in a C. elegans Model of polyQ Aggregation and Extends Lifespan, Reduces Striatal Atrophy and Improves Motor Performance in the R6/2 Mouse Model of Huntington's Disease
Journal of Huntington's disease, 2012, Vol.1 (2), p.211-219
2012
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Rating Apathy in Huntington’s Disease: Patients and Companions Agree
Journal of Huntington's disease, 2015, Vol.4 (1), p.49-59
2015
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Delayed Onset and Reduced Cognitive Deficits through Pre-Conditioning with 3-Nitropropionic Acid is Dependent on Sex and CAG Repeat Length in the R6/2 Mouse Model of Huntington's Disease
Journal of Huntington's disease, 2016-01, Vol.5 (1), p.19-32
2016
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Safety and Exploratory Efficacy at 36 Months in Open-HART, an Open-Label Extension Study of Pridopidine in Huntington's Disease
Journal of Huntington's disease, 2017-01, Vol.6 (3), p.189-199
2017
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Understanding the Outcomes Measures used in Huntington Disease Pharmacological Trials: A Systematic Review
Journal of Huntington's disease, 2014, Vol.3 (3), p.233-252
2014
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Analysis of Participant Withdrawal in Huntington Disease Clinical Trials
Journal of Huntington's disease, 2017-01, Vol.6 (2), p.149-156
2017
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Antidopaminergic Medication is Associated with More Rapidly Progressive Huntington's Disease
Journal of Huntington's disease, 2015-01, Vol.4 (2), p.131-140
2015
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Assessment of chloroquine treatment for modulating autophagy flux in brain of WT and HD mice
Journal of Huntington's disease, 2014, Vol.3 (2), p.159-174
2014
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Pizotifen Activates ERK and Provides Neuroprotection in vitro and in vivo in Models of Huntington's Disease
Journal of Huntington's disease, 2012, Vol.1 (2), p.195-210
2012
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Disease Modifying Potential of Glatiramer Acetate in Huntington's Disease
Journal of Huntington's disease, 2014, Vol.3 (3), p.311-316
2014
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