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MDR1/P-glycoprotein (ABCB1) as target for RNA interference-mediated reversal of multidrug resistance

Current drug targets, 2006-07, Vol.7 (7), p.813

Lage, Hermann

2006

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Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi)

FEBS letters, 2003-06, Vol.545 (2), p.144-150

2003

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Epoxylathyrane Derivatives as MDR-Selective Compounds for Disabling Multidrug Resistance in Cancer

Frontiers in pharmacology, 2020-05, Vol.11, p.599-599

2020

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Evaluation of microarray preprocessing algorithms based on concordance with RT-PCR in clinical samples

PloS one, 2009-05, Vol.4 (5), p.e5645-e5645

2009

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Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations

International journal of cancer, 2006-04, Vol.118 (7), p.1699-1712

2006

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Comparision of the cytotoxic effects of birch bark extract, betulin and betulinic acid towards human gastric carcinoma and pancreatic carcinoma drug-sensitive and drug-resistant cell lines

Molecules (Basel, Switzerland), 2009-04, Vol.14 (4), p.1639-1651

2009

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prognostic gene expression index in ovarian cancer--validation across different independent data sets

The Journal of pathology, 2009-06, Vol.218 (2), p.273-280

2009

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ABCC2 (MRP2, cMOAT) Can Be Localized in the Nuclear Membrane of Ovarian Carcinomas and Correlates with Resistance to Cisplatin and Clinical Outcome

Clinical cancer research, 2006-12, Vol.12 (23), p.7149-7158

2006

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Interleukin-1 beta and tumor necrosis factor-alpha increase ABCG2 expression in MCF-7 breast carcinoma cell line and its mitoxantrone-resistant derivative, MCF-7/MX

Inflammation research, 2009-10, Vol.58 (10), p.669-676

2009

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Reversal of P-glycoprotein-mediated multidrug resistance in cancer cells by the c-Jun NH2-terminal kinase

Cancer research (Chicago, Ill.), 2006, Vol.66 (1), p.445-452

2006

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Complete In Vivo Reversal of the Multidrug Resistance Phenotype by Jet-injection of Anti-MDR1 Short Hairpin RNA-encoding Plasmid DNA

Molecular therapy, 2008-01, Vol.16 (1), p.178-186

2008

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A Web-Based Data Warehouse on Gene Expression in Human Malignant Melanoma

Journal of investigative dermatology, 2007-02, Vol.127 (2), p.394-399

2007

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Reversal of breast cancer resistance protein–mediated drug resistance by tryprostatin A

International journal of cancer, 2003-12, Vol.107 (5), p.721-728

2003

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Influx and efflux transport as determinants of melphalan cytotoxicity: Resistance to melphalan in MDR1 overexpressing tumor cell lines

Biochemical pharmacology, 2009-07, Vol.78 (1), p.45-53

2009

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Novel structure–activity relationships and selectivity profiling of cage dimeric 1,4-dihydropyridines as multidrug resistance (MDR) modulators

Bioorganic & medicinal chemistry, 2010-07, Vol.18 (14), p.4983-4990

2010

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Occurence of Stromal Myofibroblasts in the Invasive Ductal Breast Cancer Tissue is an Unfavourable Prognostic Factor

Anticancer research, 2007-07, Vol.27 (4C), p.2917-2924

2007

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Reversal of different drug-resistant phenotypes by an autocatalytic multitarget multiribozyme directed against the transcripts of the ABC transporters MDR1/P-gp, MRP2, and BCRP

Molecular therapy, 2005-04, Vol.11 (4), p.508-522

2005

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Nanolipoparticles-mediated MDR1 siRNA delivery reduces doxorubicin resistance in breast cancer cells and silences MDR1 expression in xenograft model of human breast cancer

Iranian journal of basic medical sciences, 2015-04, Vol.18 (4), p.385-392

2015

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Delivery of short hairpin RNAs by transkingdom RNA interference modulates the classical ABCB1-mediated multidrug-resistant phenotype of cancer cells

Cell cycle (Georgetown, Tex.), 2009-10, Vol.8 (20), p.3349-3354

2009

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Enhanced exposure of phosphatidylserine in human gastric carcinoma cells overexpressing the half-size ABC transporter BCRP (ABCG2)

Biochemical journal, 2003-12, Vol.376 (Pt 2), p.489-495

2003

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Stable and complete overcoming of MDR1 P-glycoprotein-mediated multidrug resistance in human gastric carcinoma cells by RNA interference

Cancer gene therapy, 2004-11, Vol.11 (11), p.699-706

2004

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Gene Therapeutic Approaches to Overcome ABCB1-Mediated Drug Resistance

Current Strategies in Cancer Gene Therapy, 2016, Vol.209, p.87-94

Lage, Hermann

2016

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Estrogen Receptor Alpha Expression in Ovarian Cancer Predicts Longer Overall Survival

Pathology oncology research, 2011-09, Vol.17 (3), p.511-518

2011

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Bacteria-mediated delivery of RNAi effector molecules against viral HPV16-E7 eradicates oral squamous carcinoma cells (OSCC) via apoptosis

Cancer gene therapy, 2019-05, Vol.26 (5-6), p.166-173

2019

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Novel Insight in Structure−Activity Relationship and Bioanalysis of P-Glycoprotein Targeting Highly Potent Tetrakishydroxymethyl Substituted 3,9-Diazatetraasteranes

Journal of medicinal chemistry, 2008-09, Vol.51 (18), p.5871-5874

2008

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MDR1/P-glycoprotein (ABCB1) as target for RNA interference-mediated reversal of multidrug resistance

Modulation of the classical multidrug resistance (MDR) phenotype by RNA interference (RNAi)

Epoxylathyrane Derivatives as MDR-Selective Compounds for Disabling Multidrug Resistance in Cancer

Evaluation of microarray preprocessing algorithms based on concordance with RT-PCR in clinical samples

Gene expression profiling of 30 cancer cell lines predicts resistance towards 11 anticancer drugs at clinically achieved concentrations

Comparision of the cytotoxic effects of birch bark extract, betulin and betulinic acid towards human gastric carcinoma and pancreatic carcinoma drug-sensitive and drug-resistant cell lines

prognostic gene expression index in ovarian cancer--validation across different independent data sets

ABCC2 (MRP2, cMOAT) Can Be Localized in the Nuclear Membrane of Ovarian Carcinomas and Correlates with Resistance to Cisplatin and Clinical Outcome

Interleukin-1 beta and tumor necrosis factor-alpha increase ABCG2 expression in MCF-7 breast carcinoma cell line and its mitoxantrone-resistant derivative, MCF-7/MX

Reversal of P-glycoprotein-mediated multidrug resistance in cancer cells by the c-Jun NH2-terminal kinase

Complete In Vivo Reversal of the Multidrug Resistance Phenotype by Jet-injection of Anti-MDR1 Short Hairpin RNA-encoding Plasmid DNA

A Web-Based Data Warehouse on Gene Expression in Human Malignant Melanoma

Reversal of breast cancer resistance protein–mediated drug resistance by tryprostatin A

Influx and efflux transport as determinants of melphalan cytotoxicity: Resistance to melphalan in MDR1 overexpressing tumor cell lines

Novel structure–activity relationships and selectivity profiling of cage dimeric 1,4-dihydropyridines as multidrug resistance (MDR) modulators

Occurence of Stromal Myofibroblasts in the Invasive Ductal Breast Cancer Tissue is an Unfavourable Prognostic Factor

Reversal of different drug-resistant phenotypes by an autocatalytic multitarget multiribozyme directed against the transcripts of the ABC transporters MDR1/P-gp, MRP2, and BCRP

Nanolipoparticles-mediated MDR1 siRNA delivery reduces doxorubicin resistance in breast cancer cells and silences MDR1 expression in xenograft model of human breast cancer

Delivery of short hairpin RNAs by transkingdom RNA interference modulates the classical ABCB1-mediated multidrug-resistant phenotype of cancer cells

Enhanced exposure of phosphatidylserine in human gastric carcinoma cells overexpressing the half-size ABC transporter BCRP (ABCG2)

Stable and complete overcoming of MDR1 P-glycoprotein-mediated multidrug resistance in human gastric carcinoma cells by RNA interference

Gene Therapeutic Approaches to Overcome ABCB1-Mediated Drug Resistance

Estrogen Receptor Alpha Expression in Ovarian Cancer Predicts Longer Overall Survival

Bacteria-mediated delivery of RNAi effector molecules against viral HPV16-E7 eradicates oral squamous carcinoma cells (OSCC) via apoptosis

Novel Insight in Structure−Activity Relationship and Bioanalysis of P-Glycoprotein Targeting Highly Potent Tetrakishydroxymethyl Substituted 3,9-Diazatetraasteranes

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