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Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations

PloS one, 2011-04, Vol.6 (4), p.e18438

2011

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Influence of Phenotype at Diagnosis and of Other Potential Prognostic Factors on the Course of Inflammatory Bowel Disease

The American journal of gastroenterology, 2009-02, Vol.104 (2), p.371-383

2009

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Development of a physiologically-based pharmacokinetic pediatric brain model for prediction of cerebrospinal fluid drug concentrations and the influence of meningitis

PLoS computational biology, 2019-06, Vol.15 (6), p.e1007117

2019

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Increased Discontinuation Rates of Anti-TNF Therapy in Elderly Inflammatory Bowel Disease Patients

Journal of Crohn's and colitis, 2020-07, Vol.14 (7), p.888-895

2020

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Usage patterns of personal care products: Important factors for exposure assessment

Food and chemical toxicology, 2013-05, Vol.55, p.8-17

2013

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Physiologically based pharmacokinetic/pharmacodynamic model for the prediction of morphine brain disposition and analgesia in adults and children

PLoS computational biology, 2021-03, Vol.17 (3), p.e1008786

2021

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Inhibitory Potential of Antifungal Drugs on ATP-Binding Cassette Transporters P-Glycoprotein, MRP1 to MRP5, BCRP, and BSEP

Antimicrobial agents and chemotherapy, 2016-06, Vol.60 (6), p.3372-3379

2016

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Brothers in Arms: ABCA1- and ABCG1-Mediated Cholesterol Efflux as Promising Targets in Cardiovascular Disease Treatment

Pharmacological reviews, 2020-01, Vol.72 (1), p.152-190

2020

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Uremic Solutes in Chronic Kidney Disease and Their Role in Progression

PloS one, 2016-12, Vol.11 (12), p.e0168117

2016

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Mitochondrial complex III activity: from invasive muscle biopsies to patient-friendly buccal swab analysis

Scientific reports, 2023-06, Vol.13 (1), p.9638-9638, Article 9638

2023

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Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates

Archives of toxicology, 2020-09, Vol.94 (9), p.3027-3032

2020

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Selective iNOS inhibition for the treatment of sepsis-induced acute kidney injury

Nature reviews. Nephrology, 2009-11, Vol.5 (11), p.629-640

2009

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Effects of allopurinol and febuxostat on uric acid transport and transporter expression in human umbilical vein endothelial cells

PloS one, 2024-06, Vol.19 (6), p.e0305906

2024

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Statin Lactonization by Uridine 5′-Diphospho-glucuronosyltransferases (UGTs)

Molecular pharmaceutics, 2015-11, Vol.12 (11), p.4048-4055

2015

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Intravenously administered short interfering RNA accumulates in the kidney and selectively suppresses gene function in renal proximal tubules

Drug metabolism and disposition, 2006-08, Vol.34 (8), p.1393-1397

2006

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Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones

Cell and tissue research, 2012-08, Vol.349 (2), p.551-563

2012

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Prediction of Fetal Darunavir Exposure by Integrating Human Ex-Vivo Placental Transfer and Physiologically Based Pharmacokinetic Modeling

Clinical pharmacokinetics, 2018-06, Vol.57 (6), p.705-716

2018

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Transporter-Mediated Cellular Distribution of Tyrosine Kinase Inhibitors as a Potential Resistance Mechanism in Chronic Myeloid Leukemia

Pharmaceutics, 2023-10, Vol.15 (11), p.2535

2023

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Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates

Malaria journal, 2017-10, Vol.16 (1), p.422-12, Article 422

2017

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Statins and Cardiomyocyte Metabolism, Friend or Foe?

Journal of cardiovascular development and disease, 2023-10, Vol.10 (10), p.417

2023

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The ABCs of multidrug resistance in malaria

Trends in parasitology, 2010-09, Vol.26 (9), p.440-446

2010

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The role of ATP binding cassette transporters in tissue defense and organ regeneration

The Journal of pharmacology and experimental therapeutics, 2009-01, Vol.328 (1), p.3-9

2009

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Involvement of VDAC, Bax and ceramides in the efflux of AIF from mitochondria during curcumin-induced apoptosis

PloS one, 2009-08, Vol.4 (8), p.e6688

2009

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AMAP, the alleged non-toxic isomer of acetaminophen, is toxic in rat and human liver

Archives of toxicology, 2013-01, Vol.87 (1), p.155-165

2013

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Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4

British journal of pharmacology, 2008-12, Vol.155 (7), p.1066-1075

2008

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Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations

Influence of Phenotype at Diagnosis and of Other Potential Prognostic Factors on the Course of Inflammatory Bowel Disease

Development of a physiologically-based pharmacokinetic pediatric brain model for prediction of cerebrospinal fluid drug concentrations and the influence of meningitis

Increased Discontinuation Rates of Anti-TNF Therapy in Elderly Inflammatory Bowel Disease Patients

Usage patterns of personal care products: Important factors for exposure assessment

Physiologically based pharmacokinetic/pharmacodynamic model for the prediction of morphine brain disposition and analgesia in adults and children

Inhibitory Potential of Antifungal Drugs on ATP-Binding Cassette Transporters P-Glycoprotein, MRP1 to MRP5, BCRP, and BSEP

Brothers in Arms: ABCA1- and ABCG1-Mediated Cholesterol Efflux as Promising Targets in Cardiovascular Disease Treatment

Uremic Solutes in Chronic Kidney Disease and Their Role in Progression

Mitochondrial complex III activity: from invasive muscle biopsies to patient-friendly buccal swab analysis

Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates

Selective iNOS inhibition for the treatment of sepsis-induced acute kidney injury

Effects of allopurinol and febuxostat on uric acid transport and transporter expression in human umbilical vein endothelial cells

Statin Lactonization by Uridine 5′-Diphospho-glucuronosyltransferases (UGTs)

Intravenously administered short interfering RNA accumulates in the kidney and selectively suppresses gene function in renal proximal tubules

Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones

Prediction of Fetal Darunavir Exposure by Integrating Human Ex-Vivo Placental Transfer and Physiologically Based Pharmacokinetic Modeling

Transporter-Mediated Cellular Distribution of Tyrosine Kinase Inhibitors as a Potential Resistance Mechanism in Chronic Myeloid Leukemia

Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates

Statins and Cardiomyocyte Metabolism, Friend or Foe?

The ABCs of multidrug resistance in malaria

The role of ATP binding cassette transporters in tissue defense and organ regeneration

Involvement of VDAC, Bax and ceramides in the efflux of AIF from mitochondria during curcumin-induced apoptosis

AMAP, the alleged non-toxic isomer of acetaminophen, is toxic in rat and human liver

Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4

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