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Noncoding RNA actions through IGFs and IGF binding proteins in cancer

Oncogene, 2022-06, Vol.41 (25), p.3385-3393

2022

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CHK1 inhibition exacerbates replication stress induced by IGF blockade

Oncogene, 2022-01, Vol.41 (4), p.476-488

2022

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A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS Fli1-regulated microRNAs

Oncogene, 2011-12, Vol.30 (49), p.4910-4920

2011

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IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR

Oncogene, 2011-05, Vol.30 (20), p.2345-2355

2011

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IGF-II induces rapid β-catenin relocation to the nucleus during epithelium to mesenchyme transition

Oncogene, 2001-08, Vol.20 (36), p.4942-4950

2001

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Transgenic IGF-IR overexpression induces mammary tumors with basal-like characteristics, whereas IGF-IR-independent mammary tumors express a claudin-low gene signature

Oncogene, 2012-07, Vol.31 (27), p.3298-3309

2012

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Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation

Oncogene, 2007-03, Vol.26 (11), p.1636-1644

2007

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Overproduction of IGF-2 drives a subset of colorectal cancer cells, which specifically respond to an anti-IGF therapeutic antibody and combination therapies

Oncogene, 2017-02, Vol.36 (6), p.797-806

2017

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IGF-II and IGFBP-2 differentially regulate PTEN in human breast cancer cells

Oncogene, 2007-08, Vol.26 (40), p.5966-5972

2007

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In IGF-I receptor-deficient leiomyosarcoma cells autocrine IGF-II induces cell invasion and protection from apoptosis via the insulin receptor isoform A

Oncogene, 2002-11, Vol.21 (54), p.8240-8250

2002

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Reversibility and recurrence of IGF-IR-induced mammary tumors

Oncogene, 2009-05, Vol.28 (21), p.2152-2162

2009

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Insulin receptor activation by IGF-II in breast cancers : evidence for a new autocrine/paracrine mechanism

Oncogene, 1999-04, Vol.18 (15), p.2471-2479

1999

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PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells

Oncogene, 2004-01, Vol.23 (3), p.786-794

2004

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BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF

Oncogene, 2003-07, Vol.22 (30), p.4734-4744

2003

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Preneoplastic changes persist after IGF-IR downregulation and tumor regression

Oncogene, 2010-08, Vol.29 (34), p.4779-4786

2010

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Loss of responsiveness to IGF-I in cells with reduced cathepsin L expression levels

Oncogene, 2008-08, Vol.27 (37), p.4973-4985

2008

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Inhibition of IGF-I receptor in anchorage-independence attenuates GSK-3β constitutive phosphorylation and compromises growth and survival of medulloblastoma cell lines

Oncogene, 2007-04, Vol.26 (16), p.2308-2317

2007

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Tumor suppressors govern insulin-like growth factor signaling pathways: implications in metabolism and cancer

Oncogene, 2012-05, Vol.31 (22), p.2703-2714

Werner, H

2012

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IGF-II induces CREB phosphorylation and cell survival in human lung cancer cells

Oncogene, 2005-11, Vol.24 (49), p.7310-7319

2005

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Transgenic overexpression of IGF-II induces spontaneous lung tumors: a model for human lung adenocarcinoma

Oncogene, 2003-02, Vol.22 (6), p.853-857

2003

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IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination

Oncogene, 2014-11, Vol.33 (45), p.5262-5273

2014

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Levels of PTEN protein modulate Akt phosphorylation on serine 473, but not on threonine 308, in IGF-II-overexpressing rhabdomyosarcomas cells

Oncogene, 2003-11, Vol.22 (50), p.8205-8211

2003

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The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival

Oncogene, 2010-01, Vol.29 (2), p.251-262

2010

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Transformation by the simian virus 40 T antigen is regulated by IGF-I receptor and IRS-1 signaling

Oncogene, 2006-01, Vol.25 (1), p.32-42

2006

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Gene expression profiles in cells transformed by overexpression of the IGF-I receptor

Oncogene, 2005-09, Vol.24 (40), p.6185-6193

2005

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Noncoding RNA actions through IGFs and IGF binding proteins in cancer

CHK1 inhibition exacerbates replication stress induced by IGF blockade

A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS Fli1-regulated microRNAs

IL-6 promotes prostate tumorigenesis and progression through autocrine cross-activation of IGF-IR

IGF-II induces rapid β-catenin relocation to the nucleus during epithelium to mesenchyme transition

Transgenic IGF-IR overexpression induces mammary tumors with basal-like characteristics, whereas IGF-IR-independent mammary tumors express a claudin-low gene signature

Transgenic overexpression of IGF-IR disrupts mammary ductal morphogenesis and induces tumor formation

Overproduction of IGF-2 drives a subset of colorectal cancer cells, which specifically respond to an anti-IGF therapeutic antibody and combination therapies

IGF-II and IGFBP-2 differentially regulate PTEN in human breast cancer cells

In IGF-I receptor-deficient leiomyosarcoma cells autocrine IGF-II induces cell invasion and protection from apoptosis via the insulin receptor isoform A

Reversibility and recurrence of IGF-IR-induced mammary tumors

Insulin receptor activation by IGF-II in breast cancers : evidence for a new autocrine/paracrine mechanism

PTEN inhibits cell proliferation and induces apoptosis by downregulating cell surface IGF-IR expression in prostate cancer cells

BNIP3 plays a role in hypoxic cell death in human epithelial cells that is inhibited by growth factors EGF and IGF

Preneoplastic changes persist after IGF-IR downregulation and tumor regression

Loss of responsiveness to IGF-I in cells with reduced cathepsin L expression levels

Inhibition of IGF-I receptor in anchorage-independence attenuates GSK-3β constitutive phosphorylation and compromises growth and survival of medulloblastoma cell lines

Tumor suppressors govern insulin-like growth factor signaling pathways: implications in metabolism and cancer

IGF-II induces CREB phosphorylation and cell survival in human lung cancer cells

Transgenic overexpression of IGF-II induces spontaneous lung tumors: a model for human lung adenocarcinoma

IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination

Levels of PTEN protein modulate Akt phosphorylation on serine 473, but not on threonine 308, in IGF-II-overexpressing rhabdomyosarcomas cells

The type I insulin-like growth factor receptor regulates cancer metastasis independently of primary tumor growth by promoting invasion and survival

Transformation by the simian virus 40 T antigen is regulated by IGF-I receptor and IRS-1 signaling

Gene expression profiles in cells transformed by overexpression of the IGF-I receptor

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