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Analysis of Non-linear Pharmacokinetics of P-Glycoprotein Substrates in a Microfluidic Device Using a Mathematical Model that Includes an Unstirred Water Layer (UWL) Compartment

Pharmaceutical research, 2021-06, Vol.38 (6), p.1031-1039

2021

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Unstirred Water Layers and the Kinetics of Organic Cation Transport

Pharmaceutical research, 2015-09, Vol.32 (9), p.2937-2949

2015

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Lipid Absorption Triggers Drug Supersaturation at the Intestinal Unstirred Water Layer and Promotes Drug Absorption from Mixed Micelles

Pharmaceutical research, 2013-12, Vol.30 (12), p.3045-3058

2013

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Effect of surface charge, particle size, and modification by polyethylene glycol of liposomes on their association with Caco-2 cells across an unstirred water layer

Pharmazie, 2018-01, Vol.73 (1), p.3-8

2018

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Drug permeation through biomembranes: cyclodextrins and the unstirred water layer

Pharmazie, 2012-05, Vol.67 (5), p.363-370

Loftsson, T

2012

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Interaction with biliary and pancreatic fluids drives supersaturation and drug absorption from lipid-based formulations of low (saquinavir) and high (fenofibrate) permeability poorly soluble drugs

Journal of controlled release, 2021-03, Vol.331, p.45-61

2021

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Liquid–liquid phase separation drug aggregate: Merit for oral delivery of amorphous solid dispersions

Journal of controlled release, 2023-01, Vol.353, p.42-50

2023

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Solubility and permeability of steroids in water in the presence of potassium halides

Pharmazie, 2010-02, Vol.65 (2), p.83-85

2010

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Influence of anesthetic regimens on intestinal absorption in rats

Pharmaceutical research, 1993-06, Vol.10 (6), p.884-888

1993

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Characterization of the unstirred water layer in caco-2 cell monolayers using a novel diffusion apparatus

Pharmaceutical research, 1991-02, Vol.8 (2), p.222-227

1991

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Gastrointestinal contents in fasted state and post-lipid ingestion: In vivo measurements and in vitro models for studying oral drug delivery

Journal of controlled release, 2011-04, Vol.151 (2), p.110-122

2011

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Ionization, lipophilicity, and molecular modeling to investigate permeability and other biological properties of amlodipine

Bioorganic & medicinal chemistry, 2004-12, Vol.12 (23), p.6107-6118

2004

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The Asymmetry of the Unstirred Water Layer in Permeability Experiments

Pharmaceutical research, 2008-07, Vol.25 (7), p.1714-1722

2008

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Lipid-Based Formulations and Drug Supersaturation: Harnessing the Unique Benefits of the Lipid Digestion/Absorption Pathway

Pharmaceutical research, 2013-12, Vol.30 (12), p.2976-2992

2013

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Rate-Limiting Steps of Oral Absorption for Poorly Water-Soluble Drugs in Dogs; Prediction from a Miniscale Dissolution Test and a Physiologically-Based Computer Simulation

Pharmaceutical research, 2008-10, Vol.25 (10), p.2334-2344

2008

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Prediction of Oral Drug Absorption in Rats from In Vitro Data

Pharmaceutical research, 2023-02, Vol.40 (2), p.359-373

2023

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Oral absorption of poorly water-soluble drugs: computer simulation of fraction absorbed in humans from a miniscale dissolution test

Pharmaceutical research, 2006-06, Vol.23 (6), p.1144-1156

2006

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In Situ Artificial Membrane Permeation Assay under Hydrodynamic Control: Permeability-pH Profiles of Warfarin and Verapamil

Pharmaceutical research, 2010-08, Vol.27 (8), p.1644-1658

2010

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Drug Permeability Profiling Using the Novel Permeapad® 96-Well Plate

Pharmaceutical research, 2020-05, Vol.37 (6), p.93-93, Article 93

2020

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Physiologically Based Biopharmaceutics Model for Selumetinib Food Effect Investigation and Capsule Dissolution Safe Space – Part I: Adults

Pharmaceutical research, 2023-02, Vol.40 (2), p.387-403

2023

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Methodologies to Assess Drug Permeation Through the Blood–Brain Barrier for Pharmaceutical Research

Pharmaceutical research, 2013-11, Vol.30 (11), p.2729-2756

2013

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Challenges of Using In Vitro Data for Modeling P-Glycoprotein Efflux in the Blood-Brain Barrier

Pharmaceutical research, 2014, Vol.31 (1), p.1-19

2014

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Mucins are Involved in the Intestinal Permeation of Lipophilic Drugs in the Proximal Region of Rat Small Intestine

Pharmaceutical research, 2019-11, Vol.36 (11), p.1-11, Article 162

2019

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The Effect of Anesthetic Regimens on Intestinal Absorption of Passively Absorbed Drugs in Rats

Pharmaceutical research, 2020-05, Vol.37 (5), p.87-87, Article 87

2020

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UniORV, a New Multi-Unit Dosage Form, Improved Biopharmaceutical Properties of Tacrolimus in Rats and Humans

Pharmaceutical research, 2020-03, Vol.37 (3), p.64-64, Article 64

2020

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Analysis of Non-linear Pharmacokinetics of P-Glycoprotein Substrates in a Microfluidic Device Using a Mathematical Model that Includes an Unstirred Water Layer (UWL) Compartment

Unstirred Water Layers and the Kinetics of Organic Cation Transport

Lipid Absorption Triggers Drug Supersaturation at the Intestinal Unstirred Water Layer and Promotes Drug Absorption from Mixed Micelles

Effect of surface charge, particle size, and modification by polyethylene glycol of liposomes on their association with Caco-2 cells across an unstirred water layer

Drug permeation through biomembranes: cyclodextrins and the unstirred water layer

Interaction with biliary and pancreatic fluids drives supersaturation and drug absorption from lipid-based formulations of low (saquinavir) and high (fenofibrate) permeability poorly soluble drugs

Liquid–liquid phase separation drug aggregate: Merit for oral delivery of amorphous solid dispersions

Solubility and permeability of steroids in water in the presence of potassium halides

Influence of anesthetic regimens on intestinal absorption in rats

Characterization of the unstirred water layer in caco-2 cell monolayers using a novel diffusion apparatus

Gastrointestinal contents in fasted state and post-lipid ingestion: In vivo measurements and in vitro models for studying oral drug delivery

Ionization, lipophilicity, and molecular modeling to investigate permeability and other biological properties of amlodipine

The Asymmetry of the Unstirred Water Layer in Permeability Experiments

Lipid-Based Formulations and Drug Supersaturation: Harnessing the Unique Benefits of the Lipid Digestion/Absorption Pathway

Rate-Limiting Steps of Oral Absorption for Poorly Water-Soluble Drugs in Dogs; Prediction from a Miniscale Dissolution Test and a Physiologically-Based Computer Simulation

Prediction of Oral Drug Absorption in Rats from In Vitro Data

Oral absorption of poorly water-soluble drugs: computer simulation of fraction absorbed in humans from a miniscale dissolution test

In Situ Artificial Membrane Permeation Assay under Hydrodynamic Control: Permeability-pH Profiles of Warfarin and Verapamil

Drug Permeability Profiling Using the Novel Permeapad® 96-Well Plate

Physiologically Based Biopharmaceutics Model for Selumetinib Food Effect Investigation and Capsule Dissolution Safe Space – Part I: Adults

Methodologies to Assess Drug Permeation Through the Blood–Brain Barrier for Pharmaceutical Research

Challenges of Using In Vitro Data for Modeling P-Glycoprotein Efflux in the Blood-Brain Barrier

Mucins are Involved in the Intestinal Permeation of Lipophilic Drugs in the Proximal Region of Rat Small Intestine

The Effect of Anesthetic Regimens on Intestinal Absorption of Passively Absorbed Drugs in Rats

UniORV, a New Multi-Unit Dosage Form, Improved Biopharmaceutical Properties of Tacrolimus in Rats and Humans

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