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Studying the effect of solubilizing agents on drug diffusion through the unstirred water layer (UWL) by localized spectroscopy

European journal of pharmaceutics and biopharmaceutics, 2019-06, Vol.139, p.205-212

2019

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Analysis of Non-linear Pharmacokinetics of P-Glycoprotein Substrates in a Microfluidic Device Using a Mathematical Model that Includes an Unstirred Water Layer (UWL) Compartment

Pharmaceutical research, 2021-06, Vol.38 (6), p.1031-1039

2021

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Unstirred Water Layers and the Kinetics of Organic Cation Transport

Pharmaceutical research, 2015-09, Vol.32 (9), p.2937-2949

2015

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Towards a better mechanistic comprehension of drug permeation and absorption: Introducing the diffusion-partitioning interplay

International journal of pharmaceutics, 2021-10, Vol.608, p.121116-121116, Article 121116

2021

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Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins

International journal of pharmaceutics, 2007-09, Vol.342 (1), p.250-253

2007

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Lipid Absorption Triggers Drug Supersaturation at the Intestinal Unstirred Water Layer and Promotes Drug Absorption from Mixed Micelles

Pharmaceutical research, 2013-12, Vol.30 (12), p.3045-3058

2013

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Combined effects of the drug distribution and mucus diffusion properties of self-microemulsifying drug delivery systems on the oral absorption of fenofibrate

International journal of pharmaceutics, 2018-07, Vol.546 (1-2), p.263-271

2018

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Effect of surface charge, particle size, and modification by polyethylene glycol of liposomes on their association with Caco-2 cells across an unstirred water layer

Pharmazie, 2018-01, Vol.73 (1), p.3-8

2018

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Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid

European journal of pharmaceutical sciences, 2010-05, Vol.40 (2), p.118-124

2010

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Physicochemical properties of water and its effect on drug delivery A commentary

International journal of pharmaceutics, 2008-04, Vol.354 (1-2), p.248-254

2008

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In vitro-in vivo correlation in the effect of cyclodextrin on oral absorption of poorly soluble drugs

International journal of pharmaceutics, 2021-05, Vol.600, p.120494-120494, Article 120494

2021

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Bridging in vitro dissolution and in vivo exposure for acalabrutinib. Part I. Mechanistic modelling of drug product dissolution to derive a P-PSD for PBPK model input

European journal of pharmaceutics and biopharmaceutics, 2019-09, Vol.142, p.421-434

2019

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Dose-Dependent Solubility-Permeability Interplay for Poorly Soluble Drugs under Non-Sink Conditions

Pharmaceutics, 2021-03, Vol.13 (3), p.323

2021

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The elucidation of key factors for oral absorption enhancement of nanocrystal formulations: In vitro–in vivo correlation of nanocrystals

European journal of pharmaceutics and biopharmaceutics, 2020-01, Vol.146, p.84-92

2020

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Evaluation of the artificial membrane permeability of drugs by digital simulation

European journal of pharmaceutical sciences, 2016-08, Vol.91, p.154-161

2016

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Nasal powders of quercetin-β-cyclodextrin derivatives complexes with mannitol/lecithin microparticles for Nose-to-Brain delivery: In vitro and ex vivo evaluation

International journal of pharmaceutics, 2021-09, Vol.607, p.121016-121016, Article 121016

2021

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In vitro dissolution testing of respirable size anti-tubercular drug particles using a small volume dissolution apparatus

International journal of pharmaceutics, 2019-03, Vol.559, p.235-244

2019

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Experimental estimation of the effective unstirred water layer thickness in the human jejunum, and its importance in oral drug absorption

European journal of pharmaceutical sciences, 1995-10, Vol.3 (5), p.247-253

1995

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Interaction with biliary and pancreatic fluids drives supersaturation and drug absorption from lipid-based formulations of low (saquinavir) and high (fenofibrate) permeability poorly soluble drugs

Journal of controlled release, 2021-03, Vol.331, p.45-61

2021

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Non-Effective Improvement of Absorption for Some Nanoparticle Formulations Explained by Permeability under Non-Sink Conditions

Pharmaceutics, 2022-04, Vol.14 (4), p.816

2022

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Liquid–liquid phase separation drug aggregate: Merit for oral delivery of amorphous solid dispersions

Journal of controlled release, 2023-01, Vol.353, p.42-50

2023

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Understanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdles

Acta pharmaceutica Sinica. B, 2017-05, Vol.7 (3), p.260-280

2017

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Solubility and permeability of steroids in water in the presence of potassium halides

Pharmazie, 2010-02, Vol.65 (2), p.83-85

2010

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PAMPA—a drug absorption in vitro model: 8. Apparent filter porosity and the unstirred water layer

European journal of pharmaceutical sciences, 2004-05, Vol.22 (1), p.33-41

2004

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Aging: its influence on the intestinal unstirred water layer thickness, surface area, and resistance in the unanesthetized rat

Canadian journal of physiology and pharmacology, 1983-12, Vol.61 (12), p.1501

1983

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Studying the effect of solubilizing agents on drug diffusion through the unstirred water layer (UWL) by localized spectroscopy

Analysis of Non-linear Pharmacokinetics of P-Glycoprotein Substrates in a Microfluidic Device Using a Mathematical Model that Includes an Unstirred Water Layer (UWL) Compartment

Unstirred Water Layers and the Kinetics of Organic Cation Transport

Towards a better mechanistic comprehension of drug permeation and absorption: Introducing the diffusion-partitioning interplay

Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins

Lipid Absorption Triggers Drug Supersaturation at the Intestinal Unstirred Water Layer and Promotes Drug Absorption from Mixed Micelles

Combined effects of the drug distribution and mucus diffusion properties of self-microemulsifying drug delivery systems on the oral absorption of fenofibrate

Effect of surface charge, particle size, and modification by polyethylene glycol of liposomes on their association with Caco-2 cells across an unstirred water layer

Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid

Physicochemical properties of water and its effect on drug delivery A commentary

In vitro-in vivo correlation in the effect of cyclodextrin on oral absorption of poorly soluble drugs

Bridging in vitro dissolution and in vivo exposure for acalabrutinib. Part I. Mechanistic modelling of drug product dissolution to derive a P-PSD for PBPK model input

Dose-Dependent Solubility-Permeability Interplay for Poorly Soluble Drugs under Non-Sink Conditions

The elucidation of key factors for oral absorption enhancement of nanocrystal formulations: In vitro–in vivo correlation of nanocrystals

Evaluation of the artificial membrane permeability of drugs by digital simulation

Nasal powders of quercetin-β-cyclodextrin derivatives complexes with mannitol/lecithin microparticles for Nose-to-Brain delivery: In vitro and ex vivo evaluation

In vitro dissolution testing of respirable size anti-tubercular drug particles using a small volume dissolution apparatus

Experimental estimation of the effective unstirred water layer thickness in the human jejunum, and its importance in oral drug absorption

Interaction with biliary and pancreatic fluids drives supersaturation and drug absorption from lipid-based formulations of low (saquinavir) and high (fenofibrate) permeability poorly soluble drugs

Non-Effective Improvement of Absorption for Some Nanoparticle Formulations Explained by Permeability under Non-Sink Conditions

Liquid–liquid phase separation drug aggregate: Merit for oral delivery of amorphous solid dispersions

Understanding peroral absorption: regulatory aspects and contemporary approaches to tackling solubility and permeability hurdles

Solubility and permeability of steroids in water in the presence of potassium halides

PAMPA—a drug absorption in vitro model: 8. Apparent filter porosity and the unstirred water layer

Aging: its influence on the intestinal unstirred water layer thickness, surface area, and resistance in the unanesthetized rat

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