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Analysis of Non-linear Pharmacokinetics of P-Glycoprotein Substrates in a Microfluidic Device Using a Mathematical Model that Includes an Unstirred Water Layer (UWL) Compartment

Pharmaceutical research, 2021-06, Vol.38 (6), p.1031-1039

2021

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Estimation of effective intestinal membrane permeability considering bile micelle solubilisation

International journal of pharmaceutics, 2009-02, Vol.368 (1-2), p.116-122

Sugano, Kiyohiko

2009

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Lactose hydrate can increase the transcellular permeability of β-naphthol in rat jejunum and ileum

Molecular biology reports, 2022-09, Vol.49 (9), p.8685-8692

2022

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Towards a better mechanistic comprehension of drug permeation and absorption: Introducing the diffusion-partitioning interplay

International journal of pharmaceutics, 2021-10, Vol.608, p.121116-121116, Article 121116

2021

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Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins

International journal of pharmaceutics, 2007-09, Vol.342 (1), p.250-253

2007

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Possible reduction of effective thickness of intestinal unstirred water layer by particle drifting effect

International journal of pharmaceutics, 2010-03, Vol.387 (1), p.103-109

Sugano, Kiyohiko

2010

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Oral delivery of lipophilic drugs: the tradeoff between solubility increase and permeability decrease when using cyclodextrin-based formulations

PloS one, 2013-07, Vol.8 (7), p.e68237-e68237

2013

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Sodium Nitroprusside Enhances Absorption in the Rat Jejunum via the Transcellular Route

The Journal of membrane biology, 2020-06, Vol.253 (3), p.221-228

2020

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Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid

European journal of pharmaceutical sciences, 2010-05, Vol.40 (2), p.118-124

2010

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Drug permeation through biomembranes: cyclodextrins and the unstirred water layer

Pharmazie, 2012-05, Vol.67 (5), p.363-370

Loftsson, T

2012

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Prediction of oral drug absorption in humans by theoretical passive absorption model

International journal of pharmaceutics, 2005-04, Vol.293 (1), p.183-192

2005

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Rheological Droplet Interface Bilayers (rheo-DIBs): Probing the Unstirred Water Layer Effect on Membrane Permeability via Spinning Disk Induced Shear Stress

Scientific reports, 2017-12, Vol.7 (1), p.17551-12, Article 17551

2017

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PAMPA—a drug absorption in vitro model: 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones

European journal of pharmaceutical sciences, 2004-03, Vol.21 (4), p.429-441

2004

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Theoretical investigation of passive intestinal membrane permeability using Monte Carlo method to generate drug-like molecule population

International journal of pharmaceutics, 2009-05, Vol.373 (1), p.55-61

Sugano, Kiyohiko

2009

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Physicochemical properties of water and its effect on drug delivery A commentary

International journal of pharmaceutics, 2008-04, Vol.354 (1-2), p.248-254

2008

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Evaluation of various PAMPA models to identify the most discriminating method for the prediction of BBB permeability

European journal of pharmaceutics and biopharmaceutics, 2010-03, Vol.74 (3), p.495-502

2010

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PAMPA--a drug absorption in vitro model. 5. Unstirred water layer in iso-pH mapping assays and pKa(flux)--optimized design (pOD-PAMPA)

European journal of pharmaceutical sciences, 2003-12, Vol.20 (4-5), p.393-402

2003

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Application of PAMPA-models to predict BBB permeability including efflux ratio, plasma protein binding and physicochemical parameters

International journal of pharmaceutics, 2010-08, Vol.395 (1), p.182-197

2010

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The elucidation of key factors for oral absorption enhancement of nanocrystal formulations: In vitro–in vivo correlation of nanocrystals

European journal of pharmaceutics and biopharmaceutics, 2020-01, Vol.146, p.84-92

2020

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Evaluation of the artificial membrane permeability of drugs by digital simulation

European journal of pharmaceutical sciences, 2016-08, Vol.91, p.154-161

2016

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Towards a unified model of passive drug permeation I: Origins of the unstirred water layer with applications to ionic permeation

European journal of pharmaceutical sciences, 2014-02, Vol.52, p.109-124

2014

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A new diffusion chamber system for the determination of drug permeability coefficients across the human intestinal epithelium that are independent of the unstirred water layer

Biochimica et biophysica acta, 1992-11, Vol.1111 (2), p.204-210

1992

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Blood–brain barrier models and their relevance for a successful development of CNS drug delivery systems: A review

European journal of pharmaceutics and biopharmaceutics, 2014-08, Vol.87 (3), p.409-432

2014

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Kinetic analysis of bile salt passage across a dialysis membrane in the presence of cereal soluble dietary fibre polymers

Food chemistry, 2012-10, Vol.134 (4), p.2007-2013

2012

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Non-Effective Improvement of Absorption for Some Nanoparticle Formulations Explained by Permeability under Non-Sink Conditions

Pharmaceutics, 2022-04, Vol.14 (4), p.816

2022

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Analysis of Non-linear Pharmacokinetics of P-Glycoprotein Substrates in a Microfluidic Device Using a Mathematical Model that Includes an Unstirred Water Layer (UWL) Compartment

Estimation of effective intestinal membrane permeability considering bile micelle solubilisation

Lactose hydrate can increase the transcellular permeability of β-naphthol in rat jejunum and ileum

Towards a better mechanistic comprehension of drug permeation and absorption: Introducing the diffusion-partitioning interplay

Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins

Possible reduction of effective thickness of intestinal unstirred water layer by particle drifting effect

Oral delivery of lipophilic drugs: the tradeoff between solubility increase and permeability decrease when using cyclodextrin-based formulations

Sodium Nitroprusside Enhances Absorption in the Rat Jejunum via the Transcellular Route

Prediction of food effect by bile micelles on oral drug absorption considering free fraction in intestinal fluid

Drug permeation through biomembranes: cyclodextrins and the unstirred water layer

Prediction of oral drug absorption in humans by theoretical passive absorption model

Rheological Droplet Interface Bilayers (rheo-DIBs): Probing the Unstirred Water Layer Effect on Membrane Permeability via Spinning Disk Induced Shear Stress

PAMPA—a drug absorption in vitro model: 7. Comparing rat in situ, Caco-2, and PAMPA permeability of fluoroquinolones

Theoretical investigation of passive intestinal membrane permeability using Monte Carlo method to generate drug-like molecule population

Physicochemical properties of water and its effect on drug delivery A commentary

Evaluation of various PAMPA models to identify the most discriminating method for the prediction of BBB permeability

PAMPA--a drug absorption in vitro model. 5. Unstirred water layer in iso-pH mapping assays and pKa(flux)--optimized design (pOD-PAMPA)

Application of PAMPA-models to predict BBB permeability including efflux ratio, plasma protein binding and physicochemical parameters

The elucidation of key factors for oral absorption enhancement of nanocrystal formulations: In vitro–in vivo correlation of nanocrystals

Evaluation of the artificial membrane permeability of drugs by digital simulation

Towards a unified model of passive drug permeation I: Origins of the unstirred water layer with applications to ionic permeation

A new diffusion chamber system for the determination of drug permeability coefficients across the human intestinal epithelium that are independent of the unstirred water layer

Blood–brain barrier models and their relevance for a successful development of CNS drug delivery systems: A review

Kinetic analysis of bile salt passage across a dialysis membrane in the presence of cereal soluble dietary fibre polymers

Non-Effective Improvement of Absorption for Some Nanoparticle Formulations Explained by Permeability under Non-Sink Conditions

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