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Safety and pharmacokinetics of pravastatin used for the prevention of preeclampsia in high-risk pregnant women: a pilot randomized controlled trial

American journal of obstetrics and gynecology, 2016-06, Vol.214 (6), p.720.e1-720.e17

2016

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A randomized pilot clinical trial of pravastatin versus placebo in pregnant patients at high risk of preeclampsia

American journal of obstetrics and gynecology, 2021-12, Vol.225 (6), p.666.e1-666.e15

2021

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EP17.28: Hemodynamic changes in uteroplacental and fetal circulation after administration of pravastatin and L‐arginine in second trimester of pregnancy

Ultrasound in obstetrics & gynecology, 2024-09, Vol.64 (S1), p.269-270

2024

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Duodenum-triggered delivery of pravastatin sodium via enteric surface-coated nanovesicular spanlastic dispersions: Development, characterization and pharmacokinetic assessments

International journal of pharmaceutics, 2015-04, Vol.483 (1-2), p.77-88

2015

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Pravastatin combination with sorafenib does not improve survival in advanced hepatocellular carcinoma

Journal of hepatology, 2019-09, Vol.71 (3), p.516-522

2019

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Effects of Pravastatin on Human Placenta, Endothelium, and Women With Severe Preeclampsia

Hypertension (Dallas, Tex. 1979), 2015-09, Vol.66 (3), p.687-697

2015

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Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants

Pharmacogenetics and genomics, 2007-08, Vol.17 (8), p.647-656

2007

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Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug Interactions

Pharmaceutical research, 2012-10, Vol.29 (10), p.2860-2873

2012

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Impact of Farnesylation Inhibitors on Survival in Hutchinson-Gilford Progeria Syndrome

Circulation (New York, N.Y.), 2014-07, Vol.130 (1), p.27-34

2014

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Statin therapy increases lipoprotein(a) levels

European heart journal, 2020-06, Vol.41 (24), p.2275-2284

2020

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Pravastatin attenuates sepsis-induced acute lung injury through decreasing pulmonary microvascular permeability via inhibition of Cav-1/eNOS pathway

International immunopharmacology, 2021-11, Vol.100, p.108077-108077, Article 108077

2021

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INOVASIA Study: A Multicenter Randomized Clinical Trial of Pravastatin to Prevent Preeclampsia in High-Risk Patients

American journal of perinatology, 2024-07, Vol.41 (9), p.1203-1211

2024

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UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019-09, Vol.1125, p.121733, Article 121733

2019

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Risk of adverse events among older adults following co-prescription of clarithromycin and statins not metabolized by cytochrome P450 3A4

Canadian Medical Association journal (CMAJ), 2015-02, Vol.187 (3), p.174-180

2015

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Biphasic influence of pravastatin on human cardiac microvascular endothelial cell functions under pathological and physiological conditions

Biochemical and biophysical research communications, 2019-04, Vol.511 (2), p.476-481

2019

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Identification of the Rate-Determining Process in the Hepatic Clearance of Atorvastatin in a Clinical Cassette Microdosing Study

Clinical pharmacology and therapeutics, 2011-10, Vol.90 (4), p.575-581

2011

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Quantitative determination of pravastatin and its metabolite 3α-hydroxy pravastatin in plasma and urine of pregnant patients by LC-MS/MS

Biomedical chromatography, 2016-04, Vol.30 (4), p.548-554

2016

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Pravastatin Versus Placebo in Pregnancies at High Risk of Term Preeclampsia

Circulation (New York, N.Y.), 2021-08, Vol.144 (9), p.670-679

2021

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Role of Complement Component C1q in the Onset of Preeclampsia in Mice

Hypertension (Dallas, Tex. 1979), 2011-10, Vol.58 (4), p.716-724

2011

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Long-Term Safety and Efficacy of Lowering Low-Density Lipoprotein Cholesterol With Statin Therapy: 20-Year Follow-Up of West of Scotland Coronary Prevention Study

Circulation (New York, N.Y.), 2016-03, Vol.133 (11), p.1073-1080

2016

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Low-Density Lipoprotein Cholesterol Lowering for the Primary Prevention of Cardiovascular Disease Among Men With Primary Elevations of Low-Density Lipoprotein Cholesterol Levels of 190 mg/dL or Above: Analyses From the WOSCOPS (West of Scotland Coronary Prevention Study) 5-Year Randomized Trial and 20-Year Observational Follow-Up

Circulation (New York, N.Y.), 2017-11, Vol.136 (20), p.1878-1891

2017

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Method development for quantitative determination of seven statins including four active metabolites by means of high-resolution tandem mass spectrometry applicable for adherence testing and therapeutic drug monitoring

Clinical chemistry and laboratory medicine, 2020-05, Vol.58 (5), p.664-672

2020

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Optimised transdermal delivery of pravastatin

International journal of pharmaceutics, 2015-12, Vol.496 (2), p.518-525

2015

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Pravastatin improves pregnancy outcomes in obstetric antiphospholipid syndrome refractory to antithrombotic therapy

The Journal of clinical investigation, 2016-08, Vol.126 (8), p.2933-2940

2016

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Pravastatin for early‐onset pre‐eclampsia: a randomised, blinded, placebo‐controlled trial

BJOG : an international journal of obstetrics and gynaecology, 2020-03, Vol.127 (4), p.478-488

2020

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Safety and pharmacokinetics of pravastatin used for the prevention of preeclampsia in high-risk pregnant women: a pilot randomized controlled trial

A randomized pilot clinical trial of pravastatin versus placebo in pregnant patients at high risk of preeclampsia

EP17.28: Hemodynamic changes in uteroplacental and fetal circulation after administration of pravastatin and L‐arginine in second trimester of pregnancy

Duodenum-triggered delivery of pravastatin sodium via enteric surface-coated nanovesicular spanlastic dispersions: Development, characterization and pharmacokinetic assessments

Pravastatin combination with sorafenib does not improve survival in advanced hepatocellular carcinoma

Effects of Pravastatin on Human Placenta, Endothelium, and Women With Severe Preeclampsia

Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants

Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug Interactions

Impact of Farnesylation Inhibitors on Survival in Hutchinson-Gilford Progeria Syndrome

Statin therapy increases lipoprotein(a) levels

Pravastatin attenuates sepsis-induced acute lung injury through decreasing pulmonary microvascular permeability via inhibition of Cav-1/eNOS pathway

INOVASIA Study: A Multicenter Randomized Clinical Trial of Pravastatin to Prevent Preeclampsia in High-Risk Patients

UHPLC-MS/MS assay for simultaneous determination of amlodipine, metoprolol, pravastatin, rosuvastatin, atorvastatin with its active metabolites in human plasma, for population-scale drug-drug interactions studies in people living with HIV

Risk of adverse events among older adults following co-prescription of clarithromycin and statins not metabolized by cytochrome P450 3A4

Biphasic influence of pravastatin on human cardiac microvascular endothelial cell functions under pathological and physiological conditions

Identification of the Rate-Determining Process in the Hepatic Clearance of Atorvastatin in a Clinical Cassette Microdosing Study

Quantitative determination of pravastatin and its metabolite 3α-hydroxy pravastatin in plasma and urine of pregnant patients by LC-MS/MS

Pravastatin Versus Placebo in Pregnancies at High Risk of Term Preeclampsia

Role of Complement Component C1q in the Onset of Preeclampsia in Mice

Long-Term Safety and Efficacy of Lowering Low-Density Lipoprotein Cholesterol With Statin Therapy: 20-Year Follow-Up of West of Scotland Coronary Prevention Study

Method development for quantitative determination of seven statins including four active metabolites by means of high-resolution tandem mass spectrometry applicable for adherence testing and therapeutic drug monitoring

Optimised transdermal delivery of pravastatin

Pravastatin improves pregnancy outcomes in obstetric antiphospholipid syndrome refractory to antithrombotic therapy

Pravastatin for early‐onset pre‐eclampsia: a randomised, blinded, placebo‐controlled trial

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