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Wnt addiction of genetically defined cancers reversed by PORCN inhibition

Oncogene, 2016-04, Vol.35 (17), p.2197-2207

2016

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Oncogenic RAS-induced CK1α drives nuclear FOXO proteolysis

Oncogene, 2018-01, Vol.37 (3), p.363-376

2018

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IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ε and Wnt/β-catenin independent inhibition of mitotic spindle formation

Oncogene, 2011-06, Vol.30 (22), p.2558-2569

2011

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Distinct routes to metastasis: plasticity-dependent and plasticity-independent pathways

Oncogene, 2016-08, Vol.35 (33), p.4302-4311

2016

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Casein kinase 1 regulates Sprouty2 in FGF–ERK signaling

Oncogene, 2015-01, Vol.34 (4), p.474-484

2015

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FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway

Cell death & disease, 2014-07, Vol.5 (7), p.e1346-e1346

2014

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An hPer2 Phosphorylation Site Mutation in Familial Advanced Sleep Phase Syndrome

Science (American Association for the Advancement of Science), 2001-02, Vol.291 (5506), p.1040-1043

2001

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Protein phosphatase 2A: a panoply of enzymes

Current Opinion in Cell Biology, 2000-04, Vol.12 (2), p.180-185

Virshup, David M

2000

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Modulation of Wnt β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer

Oncogene, 2012-01, Vol.31 (2), p.213-225

2012

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Regulation of β-Catenin Signaling by the B56 Subunit of Protein Phosphatase 2A

Science (American Association for the Advancement of Science), 1999-03, Vol.283 (5410), p.2089-2091

1999

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Phase I extension study of ETC-159 an oral PORCN inhibitor administered with bone protective treatment, in patients with advanced solid tumours

Annals of oncology, 2018-11, Vol.29, p.ix23-ix24

2018

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A Conserved Docking Motif for CK1 Binding Controls the Nuclear Localization of NFAT1

Molecular and Cellular Biology, 2004-05, Vol.24 (10), p.4184-4195

2004

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The Circadian Regulatory Proteins BMAL1 and Cryptochromes Are Substrates of Casein Kinase Iε

The Journal of biological chemistry, 2002-05, Vol.277 (19), p.17248-17254

2002

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B56-Associated Protein Phosphatase 2A Is Required For Survival and Protects from Apoptosis in Drosophila melanogaster

Molecular and Cellular Biology, 2002-06, Vol.22 (11), p.3674-3684

2002

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Reversible protein phosphorylation regulates circadian rhythms

Cold Spring Harbor Symposia on Quantitative Biology, 2007, Vol.72 (1), p.413-420

2007

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Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon

Molecular and cellular biology, 2000-07, Vol.20 (13), p.4888-4899

2000

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172 Identification of Small Molecule Inhibitors of Wnt Secretion

European journal of cancer (1990), 2012-11, Vol.48, p.52-53

2012

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Wnts are dispensable for differentiation and self-renewal of adult murine hematopoietic stem cells

Blood, 2015-08, Vol.126 (9), p.1086-1094

2015

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The B56 Family of Protein Phosphatase 2A (PP2A) Regulatory Subunits Encodes Differentiation-induced Phosphoproteins That Target PP2A to Both Nucleus and Cytoplasm

The Journal of biological chemistry, 1996-09, Vol.271 (36), p.22081-22089

1996

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Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle

The Journal of biological chemistry, 1998-06, Vol.273 (26), p.15980

1998

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Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

The EMBO journal, 2001-08, Vol.20 (15), p.4122-4131

2001

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CASEIN KINASE I: ANOTHER COG IN THE CIRCADIAN CLOCKWORKS

Chronobiology international, 2001-01, Vol.18 (3), p.389-398

2001

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PO-201 NF1 inhibits glioma cells invasion and reverts mesenchymal transition

ESMO open, 2018-07, Vol.3 (Suppl 2), p.A98-A99

2018

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Identification of Inhibitory Autophosphorylation Sites in Casein Kinase I ε

The Journal of biological chemistry, 1999-11, Vol.274 (45), p.32063-32070

1999

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Mechanism of Regulation of Casein Kinase I Activity by Group I Metabotropic Glutamate Receptors

The Journal of biological chemistry, 2002-11, Vol.277 (47), p.45393-45399

2002

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Wnt addiction of genetically defined cancers reversed by PORCN inhibition

Oncogenic RAS-induced CK1α drives nuclear FOXO proteolysis

IC261 induces cell cycle arrest and apoptosis of human cancer cells via CK1δ/ε and Wnt/β-catenin independent inhibition of mitotic spindle formation

Distinct routes to metastasis: plasticity-dependent and plasticity-independent pathways

Casein kinase 1 regulates Sprouty2 in FGF–ERK signaling

FZD7 drives in vitro aggressiveness in Stem-A subtype of ovarian cancer via regulation of non-canonical Wnt/PCP pathway

An hPer2 Phosphorylation Site Mutation in Familial Advanced Sleep Phase Syndrome

Protein phosphatase 2A: a panoply of enzymes

Modulation of Wnt β-catenin signaling and proliferation by a ferrous iron chelator with therapeutic efficacy in genetically engineered mouse models of cancer

Regulation of β-Catenin Signaling by the B56 Subunit of Protein Phosphatase 2A

Phase I extension study of ETC-159 an oral PORCN inhibitor administered with bone protective treatment, in patients with advanced solid tumours

A Conserved Docking Motif for CK1 Binding Controls the Nuclear Localization of NFAT1

The Circadian Regulatory Proteins BMAL1 and Cryptochromes Are Substrates of Casein Kinase Iε

B56-Associated Protein Phosphatase 2A Is Required For Survival and Protects from Apoptosis in Drosophila melanogaster

Reversible protein phosphorylation regulates circadian rhythms

Nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase I epsilon

172 Identification of Small Molecule Inhibitors of Wnt Secretion

Wnts are dispensable for differentiation and self-renewal of adult murine hematopoietic stem cells

The B56 Family of Protein Phosphatase 2A (PP2A) Regulatory Subunits Encodes Differentiation-induced Phosphoproteins That Target PP2A to Both Nucleus and Cytoplasm

Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

CASEIN KINASE I: ANOTHER COG IN THE CIRCADIAN CLOCKWORKS

PO-201 NF1 inhibits glioma cells invasion and reverts mesenchymal transition

Identification of Inhibitory Autophosphorylation Sites in Casein Kinase I ε

Mechanism of Regulation of Casein Kinase I Activity by Group I Metabotropic Glutamate Receptors

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