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Elucidating the mechanisms underlying protein conformational switching using NMR spectroscopy

Journal of Magnetic Resonance Open, 2022-06, Vol.10-11, p.100034-100034, Article 100034

2022

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Heterogeneous binding of the SH3 client protein to the DnaK molecular chaperone

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (31), p.E4206-E4215

2015

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Metamorphic proteins: the Janus proteins of structural biology

Open biology, 2021-04, Vol.11 (4), p.210012-210012

2021

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Defining a length scale for millisecond-timescale protein conformational exchange

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (28), p.11391-11396

2013

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Sensory Feedback Myoelectric Arm

International Journal of Mechanical and Production Engineering Research and Development, 2020, Vol.10 (3), p.10925-10936

Chandra Sekhar Ashok et al, Chandra Sekhar Ashok et al

2020

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Transient excited states of the metamorphic protein Mad2 and their implications for function

Proteins, structure, function, and bioinformatics, 2024-01

2024

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Folding of the four-helix bundle FF domain from a compact on-pathway intermediate state is governed predominantly by water motion

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (47), p.19268-19273

2012

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Characterizing Post-Translational Modifications and Their Effects on Protein Conformation Using NMR Spectroscopy

Biochemistry (Easton), 2020-01, Vol.59 (1), p.57-73

2020

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Measuring Hydroxyl Exchange Rates in Glycans Using a Synergistic Combination of Saturation Transfer and Relaxation Dispersion NMR

Journal of the American Chemical Society, 2024-02, Vol.146 (6), p.3825-3835

2024

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Studying micro to millisecond protein dynamics using simple amide 15N CEST experiments supplemented with major-state R2 and visible peak-position constraints

Journal of biomolecular NMR, 2023-08, Vol.77 (4), p.165-181

2023

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Measuring radiofrequency fields in NMR spectroscopy using offset-dependent nutation profiles

Journal of magnetic resonance (1997), 2021-09, Vol.330, p.107032-107032, Article 107032

2021

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A Universal Pattern in the Percolation and Dissipation of Protein Structural Perturbations

The journal of physical chemistry letters, 2017-10, Vol.8 (19), p.4779-4784

2017

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Order/Disorder Transitions Upon Protein Binding: A Unifying Perspective

Proteins, structure, function, and bioinformatics, 2024-08

2024

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Self-Assembly of Human Profilin‑1 Detected by Carr–Purcell–Meiboom–Gill Nuclear Magnetic Resonance (CPMG NMR) Spectroscopy

Biochemistry (Easton), 2017-02, Vol.56 (5), p.692-703

2017

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Probing excited state 1Hα chemical shifts in intrinsically disordered proteins with a triple resonance-based CEST experiment: Application to a disorder-to-order switch

Methods (San Diego, Calif.), 2023-10, Vol.218, p.198-209

2023

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Studying micro to millisecond protein dynamics using simple amide 15 N CEST experiments supplemented with major-state R 2 and visible peak-position constraints

Journal of biomolecular NMR, 2023-08, Vol.77 (4), p.165

2023

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Structure and carbohydrate recognition by the non-mitogenic lectin horcolin

Biochemistry (Easton), 2022-02, Vol.61 (6), p.464-478

2022

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A finely balanced order-disorder equilibrium sculpts the folding-binding landscape of an antibiotic sequestering protein

Proceedings of the National Academy of Sciences - PNAS, 2024-05, Vol.121 (20), p.e2318855121

2024

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Structure and Carbohydrate Recognition by the Nonmitogenic Lectin Horcolin

Biochemistry (Easton), 2022-03, Vol.61 (6), p.464-478

2022

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Conformational heterogeneity in the Hsp70 chaperone‐substrate ensemble identified from analysis of NMR‐detected titration data

Protein science, 2017-11, Vol.26 (11), p.2207-2220

2017

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Separating Dipolar and Chemical Exchange Magnetization Transfer Processes in 1 H-CEST

Angewandte Chemie International Edition, 2017-05, Vol.56 (22), p.6122-6125

2017

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Probing Invisible, Excited Protein States by Non-Uniformly Sampled Pseudo-4D CEST Spectroscopy

Angewandte Chemie (International ed.), 2015-09, Vol.54 (36), p.10507-10511

International ed. in English, 2015

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Functional regulation of an intrinsically disordered protein via a conformationally excited state

Science advances, 2023-06, Vol.9 (26), p.eadh4591-eadh4591

2023

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Evaluating the influence of initial magnetization conditions on extracted exchange parameters in NMR relaxation experiments: applications to CPMG and CEST

Journal of biomolecular NMR, 2016-08, Vol.65 (3-4), p.143-156

2016

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Viscosity-Dependent Kinetics of Protein Conformational Exchange: Microviscosity Effects and the Need for a Small Viscogen

The journal of physical chemistry. B, 2014-05, Vol.118 (17), p.4546-4551

2014

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Elucidating the mechanisms underlying protein conformational switching using NMR spectroscopy

Heterogeneous binding of the SH3 client protein to the DnaK molecular chaperone

Metamorphic proteins: the Janus proteins of structural biology

Defining a length scale for millisecond-timescale protein conformational exchange

Sensory Feedback Myoelectric Arm

Transient excited states of the metamorphic protein Mad2 and their implications for function

Folding of the four-helix bundle FF domain from a compact on-pathway intermediate state is governed predominantly by water motion

Characterizing Post-Translational Modifications and Their Effects on Protein Conformation Using NMR Spectroscopy

Measuring Hydroxyl Exchange Rates in Glycans Using a Synergistic Combination of Saturation Transfer and Relaxation Dispersion NMR

Studying micro to millisecond protein dynamics using simple amide 15N CEST experiments supplemented with major-state R2 and visible peak-position constraints

Measuring radiofrequency fields in NMR spectroscopy using offset-dependent nutation profiles

A Universal Pattern in the Percolation and Dissipation of Protein Structural Perturbations

Order/Disorder Transitions Upon Protein Binding: A Unifying Perspective

Self-Assembly of Human Profilin‑1 Detected by Carr–Purcell–Meiboom–Gill Nuclear Magnetic Resonance (CPMG NMR) Spectroscopy

Probing excited state 1Hα chemical shifts in intrinsically disordered proteins with a triple resonance-based CEST experiment: Application to a disorder-to-order switch

Studying micro to millisecond protein dynamics using simple amide 15 N CEST experiments supplemented with major-state R 2 and visible peak-position constraints

Structure and carbohydrate recognition by the non-mitogenic lectin horcolin

A finely balanced order-disorder equilibrium sculpts the folding-binding landscape of an antibiotic sequestering protein

Structure and Carbohydrate Recognition by the Nonmitogenic Lectin Horcolin

Conformational heterogeneity in the Hsp70 chaperone‐substrate ensemble identified from analysis of NMR‐detected titration data

Separating Dipolar and Chemical Exchange Magnetization Transfer Processes in 1 H-CEST

Probing Invisible, Excited Protein States by Non-Uniformly Sampled Pseudo-4D CEST Spectroscopy

Functional regulation of an intrinsically disordered protein via a conformationally excited state

Evaluating the influence of initial magnetization conditions on extracted exchange parameters in NMR relaxation experiments: applications to CPMG and CEST

Viscosity-Dependent Kinetics of Protein Conformational Exchange: Microviscosity Effects and the Need for a Small Viscogen

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