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Blocking Myc to Treat Cancer: Reflecting on Two Decades of Omomyc

Cells (Basel, Switzerland), 2020-04, Vol.9 (4), p.883

2020

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Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice

Genes & development, 2013-03, Vol.27 (5), p.504-513

2013

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MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype

Cancer discovery, 2020-04, Vol.10 (4), p.588-607

2020

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Structural and Biophysical Insights into the Function of the Intrinsically Disordered Myc Oncoprotein

Cells (Basel, Switzerland), 2020-04, Vol.9 (4), p.1038

2020

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Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology

Blood, 2012-01, Vol.119 (2), p.411-421

2012

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Tumor microenvironment: becoming sick of Myc

Cellular and molecular life sciences : CMLS, 2012-03, Vol.69 (6), p.931-934

2012

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Inhibition of MYC attenuates tumor cell self‐renewal and promotes senescence in SMARCB1‐deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo

International journal of cancer, 2019-04, Vol.144 (8), p.1983-1995

2019

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Going for a “KDIP” in colorectal cancer treatment

Clinical and translational discovery, 2022-09, Vol.2 (3), p.n/a

2022

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Ibrutinib exerts potent antifibrotic and antitumor activities in mouse models of pancreatic adenocarcinoma

Cancer research (Chicago, Ill.), 2015-04, Vol.75 (8), p.1675-1681

2015

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Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice

Mediators of Inflammation, 2015-01, Vol.2015 (2015), p.189-203-016

2015

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Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis

Nature communications, 2014-08, Vol.5 (1), p.4632-4632, Article 4632

2014

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Epigenetic SMAD3 Repression in Tumor-Associated Fibroblasts Impairs Fibrosis and Response to the Antifibrotic Drug Nintedanib in Lung Squamous Cell Carcinoma

Cancer research (Chicago, Ill.), 2020-01, Vol.80 (2), p.276-290

2020

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Biophysical characterization of the b-HLH-LZ of ΔMax, an alternatively spliced isoform of Max found in tumor cells: Towards the validation of a tumor suppressor role for the Max homodimers

PloS one, 2017-03, Vol.12 (3), p.e0174413-e0174413

2017

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The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy

PloS one, 2011-07, Vol.6 (7), p.e22284

2011

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MYC and KRAS cooperation: from historical challenges to therapeutic opportunities in cancer

Signal transduction and targeted therapy, 2024-08, Vol.9 (1), p.205-30

2024

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MYC: there is more to it than cancer

Frontiers in cell and developmental biology, 2024-03, Vol.12, p.1342872-1342872

2024

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Pharmacokinetic Analysis of Omomyc Shows Lasting Structural Integrity and Long Terminal Half-Life in Tumor Tissue

Cancers, 2023-01, Vol.15 (3), p.826

2023

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Finding MYCure

Molecular & cellular oncology, 2019-01, Vol.6 (5), p.e1618178-e1618178

2019

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Measuring MYC-Mediated Metabolism in Tumorigenesis

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2318, p.231

2021

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Modeling Pharmacological Inhibition of Mast Cell Degranulation as a Therapy for Insulinoma

Neoplasia (New York, N.Y.), 2011-11, Vol.13 (11), p.1093-IN43

2011

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Detection of Post-translational Modifications on MYC

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2318, p.69

2021

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Abstract 2923: Preclinical validation of Omomyc cell-penetrating peptides as a viable in vivo anti-Myc therapy

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2923-2923

SOUCEK, LAURA

2016

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Targeting Antitumoral Proteins to Breast Cancer by Local Administration of Functional Inclusion Bodies

Advanced science, 2019-09, Vol.6 (18), p.1900849-n/a

2019

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The long journey to bring a Myc inhibitor to the clinic

The Journal of cell biology, 2021-08, Vol.220 (8), p.1

2021

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Cell-Based Methods for the Identification of Myc-Inhibitory Small Molecules

Methods in molecular biology (Clifton, N.J.), 2021, Vol.2318, p.337

2021

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Blocking Myc to Treat Cancer: Reflecting on Two Decades of Omomyc

Inhibition of Myc family proteins eradicates KRas-driven lung cancer in mice

MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype

Structural and Biophysical Insights into the Function of the Intrinsically Disordered Myc Oncoprotein

Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology

Tumor microenvironment: becoming sick of Myc

Inhibition of MYC attenuates tumor cell self‐renewal and promotes senescence in SMARCB1‐deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo

Going for a “KDIP” in colorectal cancer treatment

Ibrutinib exerts potent antifibrotic and antitumor activities in mouse models of pancreatic adenocarcinoma

Necroptotic Cell Death Signaling and Execution Pathway: Lessons from Knockout Mice

Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis

Epigenetic SMAD3 Repression in Tumor-Associated Fibroblasts Impairs Fibrosis and Response to the Antifibrotic Drug Nintedanib in Lung Squamous Cell Carcinoma

Biophysical characterization of the b-HLH-LZ of ΔMax, an alternatively spliced isoform of Max found in tumor cells: Towards the validation of a tumor suppressor role for the Max homodimers

The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy

MYC and KRAS cooperation: from historical challenges to therapeutic opportunities in cancer

MYC: there is more to it than cancer

Pharmacokinetic Analysis of Omomyc Shows Lasting Structural Integrity and Long Terminal Half-Life in Tumor Tissue

Finding MYCure

Measuring MYC-Mediated Metabolism in Tumorigenesis

Modeling Pharmacological Inhibition of Mast Cell Degranulation as a Therapy for Insulinoma

Detection of Post-translational Modifications on MYC

Abstract 2923: Preclinical validation of Omomyc cell-penetrating peptides as a viable in vivo anti-Myc therapy

Targeting Antitumoral Proteins to Breast Cancer by Local Administration of Functional Inclusion Bodies

The long journey to bring a Myc inhibitor to the clinic

Cell-Based Methods for the Identification of Myc-Inhibitory Small Molecules

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