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Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers

The New England journal of medicine, 2009-07, Vol.361 (2), p.123-134

2009

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Piraña and PCluster: A modeling environment and cluster infrastructure for NONMEM

Computer methods and programs in biomedicine, 2011, Vol.101 (1), p.72-79

2011

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A Phase I and Pharmacological Study with Imidazolium-trans-DMSO-imidazole-tetrachlororuthenate, a Novel Ruthenium Anticancer Agent

Clinical cancer research, 2004-06, Vol.10 (11), p.3717-3727

2004

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Relationship between Single Nucleotide Polymorphisms and Haplotypes in DPYD and Toxicity and Efficacy of Capecitabine in Advanced Colorectal Cancer

Clinical cancer research, 2011-05, Vol.17 (10), p.3455-3468

2011

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Systematic review of biomarkers to monitor therapeutic response in leishmaniasis

Antimicrobial agents and chemotherapy, 2015-01, Vol.59 (1), p.1-14

2015

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Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy

Investigational new drugs, 2015-02, Vol.33 (1), p.201-214

2015

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Clinical proteomics in breast cancer: a review

Breast cancer research and treatment, 2009-07, Vol.116 (1), p.17-29

2009

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Dabrafenib plus trametinib in BRAFV600E-mutated rare cancers: the phase 2 ROAR trial

Nature medicine, 2023-05, Vol.29 (5), p.1103-1112

2023

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Poly(ADP)-Ribose Polymerase Inhibition: Frequent Durable Responses in BRCA Carrier Ovarian Cancer Correlating With Platinum-Free Interval

Journal of clinical oncology, 2010-05, Vol.28 (15), p.2512-2519

2010

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Identification of serum proteins discriminating colorectal cancer patients and healthy controls using surface-enhanced laser desorption ionisation-time of flight mass spectrometry

World journal of gastroenterology : WJG, 2006-03, Vol.12 (10), p.1536

2006

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A first-in-man phase 1 study of the DNA-dependent protein kinase inhibitor peposertib (formerly M3814) in patients with advanced solid tumours

British journal of cancer, 2021-02, Vol.124 (4), p.728-735

2021

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A phase I study of SAR405838, a novel human double minute 2 (HDM2) antagonist, in patients with solid tumours

European journal of cancer (1990), 2017-05, Vol.76, p.144-151

2017

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A Phase I and Pharmacological Study of the Platinum Polymer AP5280 Given as an Intravenous Infusion Once Every 3 Weeks in Patients with Solid Tumors

Clinical cancer research, 2004-05, Vol.10 (10), p.3386-3395

2004

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Population pharmacokinetics of doxorubicin: establishment of a NONMEM model for adults and children older than 3 years

Cancer chemotherapy and pharmacology, 2013-03, Vol.71 (3), p.749-763

2013

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Effect of the drug transporters ABCG2, Abcg2, ABCB1 and ABCC2 on the disposition, brain accumulation and myelotoxicity of the aurora kinase B inhibitor barasertib and its more active form barasertib-hydroxy-QPA

Investigational new drugs, 2013-10, Vol.31 (5), p.1125-1135

2013

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Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183

Investigational new drugs, 2014-12, Vol.32 (6), p.1083-1095

2014

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Phase 1a/1b and pharmacogenetic study of docetaxel, oxaliplatin and capecitabine in patients with advanced cancer of the stomach or the gastroesophageal junction

Cancer chemotherapy and pharmacology, 2015-12, Vol.76 (6), p.1285-1295

2015

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Liquid chromatography–tandem mass spectrometric assay for diclofenac and three primary metabolites in mouse plasma

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008-09, Vol.872 (1), p.77-82

2008

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Effectiveness and safety of reduced‐dose fluoropyrimidine therapy in patients carrying the DPYD2A variant: A matched pair analysis

International journal of cancer, 2019-05, Vol.144 (9), p.2347-2354

2019

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A phase I, open-label, randomized crossover study to assess the effect of dosing of the MEK 1/2 inhibitor Selumetinib (AZD6244; ARRY-142866) in the presence and absence of food in patients with advanced solid tumors

Cancer chemotherapy and pharmacology, 2011-12, Vol.68 (6), p.1619-1628

2011

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Severe Skin Toxicity in Pediatric Oncology Patients Treated with Voriconazole and Concomitant Methotrexate

Antimicrobial Agents and Chemotherapy, 2013-06, Vol.57 (6), p.2878-2881

2013

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Phase I Dose-Escalation Study of the Pan-HER Inhibitor, PF299804, in Patients with Advanced Malignant Solid Tumors

Clinical cancer research, 2011-03, Vol.17 (5), p.1131-1139

2011

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A sensitive combined assay for the quantification of paclitaxel, docetaxel and ritonavir in human plasma using liquid chromatography coupled with tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011-10, Vol.879 (28), p.2984-2990

2011

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Decitabine triphosphate levels in peripheral blood mononuclear cells from patients receiving prolonged low-dose decitabine administration: a pilot study

Cancer chemotherapy and pharmacology, 2012-06, Vol.69 (6), p.1457-1466

2012

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Carboplatin dosing in overweight and obese patients with normal renal function, does weight matter?

Cancer chemotherapy and pharmacology, 2009-06, Vol.64 (1), p.115-122

2009

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Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers

Piraña and PCluster: A modeling environment and cluster infrastructure for NONMEM

A Phase I and Pharmacological Study with Imidazolium-trans-DMSO-imidazole-tetrachlororuthenate, a Novel Ruthenium Anticancer Agent

Relationship between Single Nucleotide Polymorphisms and Haplotypes in DPYD and Toxicity and Efficacy of Capecitabine in Advanced Colorectal Cancer

Systematic review of biomarkers to monitor therapeutic response in leishmaniasis

Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy

Clinical proteomics in breast cancer: a review

Dabrafenib plus trametinib in BRAFV600E-mutated rare cancers: the phase 2 ROAR trial

Poly(ADP)-Ribose Polymerase Inhibition: Frequent Durable Responses in BRCA Carrier Ovarian Cancer Correlating With Platinum-Free Interval

Identification of serum proteins discriminating colorectal cancer patients and healthy controls using surface-enhanced laser desorption ionisation-time of flight mass spectrometry

A first-in-man phase 1 study of the DNA-dependent protein kinase inhibitor peposertib (formerly M3814) in patients with advanced solid tumours

A phase I study of SAR405838, a novel human double minute 2 (HDM2) antagonist, in patients with solid tumours

A Phase I and Pharmacological Study of the Platinum Polymer AP5280 Given as an Intravenous Infusion Once Every 3 Weeks in Patients with Solid Tumors

Population pharmacokinetics of doxorubicin: establishment of a NONMEM model for adults and children older than 3 years

Effect of the drug transporters ABCG2, Abcg2, ABCB1 and ABCC2 on the disposition, brain accumulation and myelotoxicity of the aurora kinase B inhibitor barasertib and its more active form barasertib-hydroxy-QPA

Effect of the drug transporters ABCB1, ABCC2, and ABCG2 on the disposition and brain accumulation of the taxane analog BMS-275,183

Phase 1a/1b and pharmacogenetic study of docetaxel, oxaliplatin and capecitabine in patients with advanced cancer of the stomach or the gastroesophageal junction

Liquid chromatography–tandem mass spectrometric assay for diclofenac and three primary metabolites in mouse plasma

Effectiveness and safety of reduced‐dose fluoropyrimidine therapy in patients carrying the DPYD2A variant: A matched pair analysis

A phase I, open-label, randomized crossover study to assess the effect of dosing of the MEK 1/2 inhibitor Selumetinib (AZD6244; ARRY-142866) in the presence and absence of food in patients with advanced solid tumors

Severe Skin Toxicity in Pediatric Oncology Patients Treated with Voriconazole and Concomitant Methotrexate

Phase I Dose-Escalation Study of the Pan-HER Inhibitor, PF299804, in Patients with Advanced Malignant Solid Tumors

A sensitive combined assay for the quantification of paclitaxel, docetaxel and ritonavir in human plasma using liquid chromatography coupled with tandem mass spectrometry

Decitabine triphosphate levels in peripheral blood mononuclear cells from patients receiving prolonged low-dose decitabine administration: a pilot study

Carboplatin dosing in overweight and obese patients with normal renal function, does weight matter?

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