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IL-22 induces an acute-phase response

The Journal of immunology (1950), 2010-11, Vol.185 (9), p.5531-5538

2010

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Marstacimab, a tissue factor pathway inhibitor neutralizing antibody, improves coagulation parameters of ex vivo dosed haemophilic blood and plasmas

Haemophilia : the official journal of the World Federation of Hemophilia, 2019-09, Vol.25 (5), p.797-806

2019

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Hemostatic efficacy of marstacimab alone or in combination with bypassing agents in hemophilia plasmas and a mouse bleeding model

Research and practice in thrombosis and haemostasis, 2022-02, Vol.6 (2), p.e12679-n/a, Article e12679

2022

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Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection

Critical care (London, England), 2007-01, Vol.11 (6), p.R122-R122, Article R122

2007

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A monoclonal antibody against RAGE alters gene expression and is protective in experimental models of sepsis and pneumococcal pneumonia

Shock (Augusta, Ga.), 2011-05, Vol.35 (5), p.492-498

2011

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Field Study and Correlative Studies of Factor IX Variant FIX-R338L in Participants Treated with Fidanacogene Elaparvovec

Thrombosis and haemostasis, 2024-10, Vol.124 (10), p.912-921

2024

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Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia

Blood, 2020-02, Vol.135 (8), p.547-557

2020

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Evaluation of Longitudinal Pain Study in Sickle Cell Disease (ELIPSIS) by patient-reported outcomes, actigraphy, and biomarkers

Blood, 2021-04, Vol.137 (15), p.2010-2020

2021

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Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis

Atherosclerosis, 2008-11, Vol.201 (1), p.53-66

2008

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Translational Pharmacokinetic/Pharmacodynamic Characterization and Target-Mediated Drug Disposition Modeling of an Anti–Tissue Factor Pathway Inhibitor Antibody, PF-06741086

Journal of pharmaceutical sciences, 2018-07, Vol.107 (7), p.1995-2004

2018

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Pharmacokinetics and lung distribution of a humanized anti-RAGE antibody in wild-type and RAGE-/- mice

mAbs, 2010-09, Vol.2 (5), p.571-575

2010

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Validation of patient‐reported vaso‐occlusive crisis day as an endpoint in sickle cell disease studies

European journal of haematology, 2022-09, Vol.109 (3), p.226-237

2022

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Induction and Impact of Anti-Drug Responses Elicited by a Human Recombinant Coagulation Factor FXaI16L in Preclinical Species

The AAPS journal, 2019-04, Vol.21 (3), p.52-52, Article 52

2019

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PF‐04447943, a Phosphodiesterase 9A Inhibitor, in Stable Sickle Cell Disease Patients: A Phase Ib Randomized, Placebo‐Controlled Study

Clinical and translational science, 2019-03, Vol.12 (2), p.180-188

2019

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A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia

Nature biotechnology, 2011-11, Vol.29 (11), p.1028-1033

2011

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Preclinical Pharmacokinetics, Pharmacodynamics, Tissue Distribution, and Interspecies Scaling of Recombinant Human Coagulation Factor Xa I16L

Journal of pharmaceutical sciences, 2017-08, Vol.106 (8), p.2136-2143

2017

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Preclinical Pharmacokinetics, Pharmacodynamics, Tissue Distribution, and Interspecies Scaling of Recombinant Human Coagulation Factor XaI16L

Journal of pharmaceutical sciences, 2017-08, Vol.106 (8), p.2136-2143

2017

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Complement C3a, CpG oligos, and DNA/C3a complex stimulate IFN-α production in a receptor for advanced glycation end product-dependent manner

The Journal of immunology (1950), 2010-10, Vol.185 (7), p.4213-4222

2010

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TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines

Rheumatology (Oxford, England), 2009-11, Vol.48 (11), p.1352-1358

2009

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Morphologic analysis of BMP-9 gene therapy-induced osteogenesis

Human gene therapy, 2001-04, Vol.12 (6), p.697-710

2001

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Inhibition of the Unfolded Protein Response by metformin in renal proximal tubular epithelial cells

Biochemical and biophysical research communications, 2011-06, Vol.409 (3), p.500-505

2011

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Effect of adenovirus-mediated overexpression of bovine ADAMTS-4 and human ADAMTS-5 in primary bovine articular chondrocyte pellet culture system

Osteoarthritis and cartilage, 2004-08, Vol.12 (8), p.599-613

2004

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Affinity Maturation of a Humanized Rat Antibody for Anti-RAGE Therapy: Comprehensive Mutagenesis Reveals a High Level of Mutational Plasticity Both Inside and Outside the Complementarity-Determining Regions

Journal of molecular biology, 2009-05, Vol.388 (3), p.541-558

2009

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Rat strain differences in the ectopic osteogenic potential of recombinant human BMP adenoviruses

Molecular therapy, 2003-11, Vol.8 (5), p.822-829

2003

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Molecular profile of peripheral blood mononuclear cells from patients with rheumatoid arthritis

Molecular medicine (Cambridge, Mass.), 2007-01, Vol.13 (1-2), p.40-58

2007

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IL-22 induces an acute-phase response

Marstacimab, a tissue factor pathway inhibitor neutralizing antibody, improves coagulation parameters of ex vivo dosed haemophilic blood and plasmas

Hemostatic efficacy of marstacimab alone or in combination with bypassing agents in hemophilia plasmas and a mouse bleeding model

Inhibition of the RAGE products increases survival in experimental models of severe sepsis and systemic infection

A monoclonal antibody against RAGE alters gene expression and is protective in experimental models of sepsis and pneumococcal pneumonia

Field Study and Correlative Studies of Factor IX Variant FIX-R338L in Participants Treated with Fidanacogene Elaparvovec

Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia

Evaluation of Longitudinal Pain Study in Sickle Cell Disease (ELIPSIS) by patient-reported outcomes, actigraphy, and biomarkers

Expression of the cysteine protease legumain in vascular lesions and functional implications in atherogenesis

Translational Pharmacokinetic/Pharmacodynamic Characterization and Target-Mediated Drug Disposition Modeling of an Anti–Tissue Factor Pathway Inhibitor Antibody, PF-06741086

Pharmacokinetics and lung distribution of a humanized anti-RAGE antibody in wild-type and RAGE-/- mice

Validation of patient‐reported vaso‐occlusive crisis day as an endpoint in sickle cell disease studies

Induction and Impact of Anti-Drug Responses Elicited by a Human Recombinant Coagulation Factor FXaI16L in Preclinical Species

PF‐04447943, a Phosphodiesterase 9A Inhibitor, in Stable Sickle Cell Disease Patients: A Phase Ib Randomized, Placebo‐Controlled Study

A zymogen-like factor Xa variant corrects the coagulation defect in hemophilia

Preclinical Pharmacokinetics, Pharmacodynamics, Tissue Distribution, and Interspecies Scaling of Recombinant Human Coagulation Factor Xa I16L

Preclinical Pharmacokinetics, Pharmacodynamics, Tissue Distribution, and Interspecies Scaling of Recombinant Human Coagulation Factor XaI16L

Complement C3a, CpG oligos, and DNA/C3a complex stimulate IFN-α production in a receptor for advanced glycation end product-dependent manner

TREM-1 expression is increased in the synovium of rheumatoid arthritis patients and induces the expression of pro-inflammatory cytokines

Morphologic analysis of BMP-9 gene therapy-induced osteogenesis

Inhibition of the Unfolded Protein Response by metformin in renal proximal tubular epithelial cells

Effect of adenovirus-mediated overexpression of bovine ADAMTS-4 and human ADAMTS-5 in primary bovine articular chondrocyte pellet culture system

Affinity Maturation of a Humanized Rat Antibody for Anti-RAGE Therapy: Comprehensive Mutagenesis Reveals a High Level of Mutational Plasticity Both Inside and Outside the Complementarity-Determining Regions

Rat strain differences in the ectopic osteogenic potential of recombinant human BMP adenoviruses

Molecular profile of peripheral blood mononuclear cells from patients with rheumatoid arthritis

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