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Key transcriptional effectors of the pancreatic acinar phenotype and oncogenic transformation

PloS one, 2023-10, Vol.18 (10), p.e0291512-e0291512

2023

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Diagnostic and Prognostic Markers for Pancreatitis and Pancreatic Ductal Adenocarcinoma

International journal of molecular sciences, 2024-06, Vol.25 (12), p.6619

2024

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Conditional Expression Demonstrates the Role of the Homeodomain Transcription Factor Pdx1 in Maintenance and Regeneration of β-Cells in the Adult Pancreas

Diabetes (New York, N.Y.), 2005-09, Vol.54 (9), p.2586-2595

2005

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Program Specificity for Ptf1a in Pancreas versus Neural Tube Development Correlates with Distinct Collaborating Cofactors and Chromatin Accessibility

Molecular and Cellular Biology, 2013-08, Vol.33 (16), p.3166-3179

2013

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Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus

PLoS biology, 2006-02, Vol.4 (2), p.e39-e39

2006

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An inflammatory transcriptional switch

Nature (London), 2018-02, Vol.554 (7693), p.470-472

2018

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Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism

Developmental cell, 2019-09, Vol.50 (6), p.744-754.e4

2019

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MIST1 and PTF1 Collaborate in Feed-Forward Regulatory Loops That Maintain the Pancreatic Acinar Phenotype in Adult Mice

Molecular and cellular biology, 2016-12, Vol.36 (23), p.2945-2955

2016

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MIST1 Links Secretion and Stress as both Target and Regulator of the Unfolded Protein Response

Molecular and cellular biology, 2016-12, Vol.36 (23), p.2931-2944

2016

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Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics

Scientific reports, 2020-11, Vol.10 (1), p.20662, Article 20662

2020

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Isolated Pancreatic Aplasia Due to a Hypomorphic PTF1A Mutation

Diabetes (New York, N.Y.), 2016-09, Vol.65 (9), p.2810-2815

2016

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PDX1 Deficiency Causes Mitochondrial Dysfunction and Defective Insulin Secretion through TFAM Suppression

Cell metabolism, 2009-08, Vol.10 (2), p.110-118

2009

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Replacement of Rbpj With Rbpjl in the PTF1 Complex Controls the Final Maturation of Pancreatic Acinar Cells

Gastroenterology (New York, N.Y. 1943), 2010-07, Vol.139 (1), p.270-280

2010

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The Parahox gene Pdx1 is required to maintain positional identity in the adult foregut

The International journal of developmental biology, 2013, Vol.57 (5), p.391-398

2013

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Notch-Independent Functions of CSL

Current Topics in Developmental Biology, 2011, Vol.97, p.55-74

2011

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Assessment of RNA Quality by Semi-Quantitative RT-PCR of Multiple Regions of a Long Ubiquitous mRNA

BioTechniques, 2000-03, Vol.28 (3), p.524-531

2000

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An Endocrine-Exocrine Switch in the Activity of the Pancreatic Homeodomain Protein PDX1 through Formation of a Trimeric Complex with PBX1b and MRG1 (MEIS2)

Molecular and Cellular Biology, 1998-09, Vol.18 (9), p.5109-5120

1998

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A comprehensive survey of DNA-binding transcription factor gene expression in human fetal and adult organs

Gene Expression Patterns, 2006-10, Vol.6 (7), p.678-686

2006

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An inflammatory transcriptional switch

Nature (London), 2018-02, Vol.554 (7693), p.470

2018

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A candidate gene for human neurodegenerative disorders: a rat PKCγ mutation causes a Parkinsonian syndrome

Nature neuroscience, 2001-11, Vol.4 (11), p.1061-1062

2001

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Key transcriptional effectors of the pancreatic acinar phenotype and oncogenic transformation

PloS one, 2023-01, Vol.18 (10)

2023

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Integration of Tetracycline Regulation into a Cell-specific Transcriptional Enhancer

The Journal of biological chemistry, 1997-02, Vol.272 (8), p.4735-4739

1997

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Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

The Journal of clinical investigation, 2012-10, Vol.122 (10), p.3516

2012

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DNA Binding and Transcriptional Activation by a PDX1·PBX1b·MEIS2b Trimer and Cooperation with a Pancreas-specific Basic Helix-Loop-Helix Complex

The Journal of biological chemistry, 2001-05, Vol.276 (21), p.17985-17993

2001

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Conditional control of pancreatic progenitor maintenance and differentiation by FGF10 uncovers an endocrine-specific competence window in development

Developmental biology, 2007-06, Vol.306 (1), p.415-415

2007

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Key transcriptional effectors of the pancreatic acinar phenotype and oncogenic transformation

Diagnostic and Prognostic Markers for Pancreatitis and Pancreatic Ductal Adenocarcinoma

Conditional Expression Demonstrates the Role of the Homeodomain Transcription Factor Pdx1 in Maintenance and Regeneration of β-Cells in the Adult Pancreas

Program Specificity for Ptf1a in Pancreas versus Neural Tube Development Correlates with Distinct Collaborating Cofactors and Chromatin Accessibility

Conditional expression of Smad7 in pancreatic beta cells disrupts TGF-beta signaling and induces reversible diabetes mellitus

An inflammatory transcriptional switch

Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism

MIST1 and PTF1 Collaborate in Feed-Forward Regulatory Loops That Maintain the Pancreatic Acinar Phenotype in Adult Mice

MIST1 Links Secretion and Stress as both Target and Regulator of the Unfolded Protein Response

Concerted cell and in vivo screen for pancreatic ductal adenocarcinoma (PDA) chemotherapeutics

Isolated Pancreatic Aplasia Due to a Hypomorphic PTF1A Mutation

PDX1 Deficiency Causes Mitochondrial Dysfunction and Defective Insulin Secretion through TFAM Suppression

Replacement of Rbpj With Rbpjl in the PTF1 Complex Controls the Final Maturation of Pancreatic Acinar Cells

The Parahox gene Pdx1 is required to maintain positional identity in the adult foregut

Notch-Independent Functions of CSL

Assessment of RNA Quality by Semi-Quantitative RT-PCR of Multiple Regions of a Long Ubiquitous mRNA

An Endocrine-Exocrine Switch in the Activity of the Pancreatic Homeodomain Protein PDX1 through Formation of a Trimeric Complex with PBX1b and MRG1 (MEIS2)

A comprehensive survey of DNA-binding transcription factor gene expression in human fetal and adult organs

An inflammatory transcriptional switch

A candidate gene for human neurodegenerative disorders: a rat PKCγ mutation causes a Parkinsonian syndrome

Key transcriptional effectors of the pancreatic acinar phenotype and oncogenic transformation

Integration of Tetracycline Regulation into a Cell-specific Transcriptional Enhancer

Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis

DNA Binding and Transcriptional Activation by a PDX1·PBX1b·MEIS2b Trimer and Cooperation with a Pancreas-specific Basic Helix-Loop-Helix Complex

Conditional control of pancreatic progenitor maintenance and differentiation by FGF10 uncovers an endocrine-specific competence window in development

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