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Rapid classification of a novel ALS-causing I149S variant in superoxide dismutase-1

Amyotrophic lateral sclerosis and frontotemporal degeneration, 2024-08, Vol.25 (5-6), p.608-614

2024

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High-content analysis of proteostasis capacity in cellular models of amyotrophic lateral sclerosis (ALS)

Scientific reports, 2024-06, Vol.14 (1), p.13844-11

2024

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Amyloidogenic regions in beta-strands II and III modulate the aggregation and toxicity of SOD1 in living cells

Open biology, 2024-06, Vol.14 (6), p.230418-17

2024

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RNA-binding properties orchestrate TDP-43 homeostasis through condensate formation in vivo

Nucleic acids research, 2024-05, Vol.52 (9), p.5301-5319

2024

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Tryptophan residues in TDP-43 and SOD1 modulate the cross-seeding and toxicity of SOD1

The Journal of biological chemistry, 2024-05, Vol.300 (5), p.107207-107207, Article 107207

2024

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Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS

PLoS biology, 2024-01, Vol.22 (1), p.e3002462, Article e3002462

2024

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ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis

Human molecular genetics, 2023-07, Vol.32 (14), p.2386-2398

2023

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Protocol for the generation and automated confocal imaging of whole multi-cellular tumor spheroids

STAR protocols, 2023-06, Vol.4 (2), p.102331-102331, Article 102331

2023

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Assessment of protein inclusions in cultured cells using automated image analysis

STAR protocols, 2022-12, Vol.3 (4), p.101748-101748, Article 101748

2022

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Cells Overexpressing ALS-Associated SOD1 Variants Are Differentially Susceptible to CuATSM-Associated Toxicity

ACS chemical neuroscience, 2022-08, Vol.13 (16), p.2371-2379

2022

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CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1 G93A mice with a C57BL/6 background

Scientific reports, 2021-09, Vol.11 (1), p.19392

2021

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CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 background

Scientific reports, 2021-09, Vol.11 (1), Article 19392

2021

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CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1 G93A mice with a C57BL/6 background

Scientific reports, 2021-09, Vol.11 (1), p.1-12

2021

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Protein Aggregation in Amyotrophic Lateral Sclerosis

Spectrums of Amyotrophic Lateral Sclerosis, 2021, p.105-121

2021

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Cerebrovascular amyloid angiopathy in bioengineered vessels is reduced by high‐density lipoprotein particles enriched in apolipoprotein E: Development of new models and analysis methods/amyloid/Abeta

Alzheimer's & dementia, 2020-12, Vol.16 (S2)

2020

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Cerebrovascular amyloid angiopathy in bioengineered vessels is reduced by high‐density lipoprotein particles enriched in apolipoprotein E

Alzheimer's & dementia, 2020-12, Vol.16, p.n/a

2020

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Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALS

iScience, 2020-11, Vol.23 (11), p.101700-101700, Article 101700

2020

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Thulium oxide nanoparticles as radioenhancers for the treatment of metastatic cutaneous squamous cell carcinoma

Physics in medicine & biology, 2020-11, Vol.65 (21), p.215018

2020

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Amyotrophic Lateral Sclerosis: Proteins, Proteostasis, Prions, and Promises

Frontiers in cellular neuroscience, 2020-11, Vol.14, p.581907-581907

2020

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Neurodegenerative disease-associated protein aggregates are poor inducers of the heat shock response in neuronal cells

Journal of cell science, 2020-08, Vol.133 (15)

2020

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Proteome Homeostasis Dysfunction: A Unifying Principle in ALS Pathogenesis

Trends in neurosciences (Regular ed.), 2020-05, Vol.43 (5), p.274-284

2020

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Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E

Molecular neurodegeneration, 2020-03, Vol.15 (1), p.23-23, Article 23

2020

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The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins

Glia, 2020-02, Vol.68 (2), p.407-421

2020

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Tryptophan residue 32 in human Cu-Zn superoxide dismutase modulates prion-like propagation and strain selection

PloS one, 2020-01, Vol.15 (1), p.e0227655

2020

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Trajectory Taken by Dimeric Cu/Zn Superoxide Dismutase through the Protein Unfolding and Dissociation Landscape Is Modulated by Salt Bridge Formation

Analytical chemistry (Washington), 2020-01, Vol.92 (2), p.1702-1711

2020

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Rapid classification of a novel ALS-causing I149S variant in superoxide dismutase-1

High-content analysis of proteostasis capacity in cellular models of amyotrophic lateral sclerosis (ALS)

Amyloidogenic regions in beta-strands II and III modulate the aggregation and toxicity of SOD1 in living cells

RNA-binding properties orchestrate TDP-43 homeostasis through condensate formation in vivo

Tryptophan residues in TDP-43 and SOD1 modulate the cross-seeding and toxicity of SOD1

Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS

ALS-linked CCNF variant disrupts motor neuron ubiquitin homeostasis

Protocol for the generation and automated confocal imaging of whole multi-cellular tumor spheroids

Assessment of protein inclusions in cultured cells using automated image analysis

Cells Overexpressing ALS-Associated SOD1 Variants Are Differentially Susceptible to CuATSM-Associated Toxicity

CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1 G93A mice with a C57BL/6 background

CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1G93A mice with a C57BL/6 background

CuATSM improves motor function and extends survival but is not tolerated at a high dose in SOD1 G93A mice with a C57BL/6 background

Protein Aggregation in Amyotrophic Lateral Sclerosis

Cerebrovascular amyloid angiopathy in bioengineered vessels is reduced by high‐density lipoprotein particles enriched in apolipoprotein E: Development of new models and analysis methods/amyloid/Abeta

Cerebrovascular amyloid angiopathy in bioengineered vessels is reduced by high‐density lipoprotein particles enriched in apolipoprotein E

Ubiquitin Homeostasis Is Disrupted in TDP-43 and FUS Cell Models of ALS

Thulium oxide nanoparticles as radioenhancers for the treatment of metastatic cutaneous squamous cell carcinoma

Amyotrophic Lateral Sclerosis: Proteins, Proteostasis, Prions, and Promises

Neurodegenerative disease-associated protein aggregates are poor inducers of the heat shock response in neuronal cells

Proteome Homeostasis Dysfunction: A Unifying Principle in ALS Pathogenesis

Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E

The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins

Tryptophan residue 32 in human Cu-Zn superoxide dismutase modulates prion-like propagation and strain selection

Trajectory Taken by Dimeric Cu/Zn Superoxide Dismutase through the Protein Unfolding and Dissociation Landscape Is Modulated by Salt Bridge Formation

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