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Synthesis of QS-21-Xylose: Establishment of the Immunopotentiating Activity of Synthetic QS-21 Adjuvant with a Melanoma Vaccine

Angewandte Chemie (International ed.), 2008-01, Vol.47 (34), p.6395-6398

2008

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Development of Improved Vaccine Adjuvants Based on the Saponin Natural Product QS-21 through Chemical Synthesis

Accounts of chemical research, 2016-09, Vol.49 (9), p.1741-1756

2016

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Synthesis of Antiproliferative Cephalotaxus Esters and Their Evaluation against Several Human Hematopoietic and Solid Tumor Cell Lines: Uncovering Differential Susceptibilities to Multidrug Resistance

Chemistry : a European journal, 2008-01, Vol.14 (14), p.4293-4306

2008

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Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer

Expert review of vaccines, 2011-04, Vol.10 (4), p.463-470

2011

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Synthesis of the hexacyclic triterpene core of the jujuboside saponins via tandem Wolff rearrangement–intramolecular ketene hetero-Diels–Alder reaction

Tetrahedron, 2018-06, Vol.74 (26), p.3370-3383

2018

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Rapid assembly of the doubly-branched pentasaccharide domain of the immunoadjuvant jujuboside A via convergent B(C 6 F 5 ) 3 -catalyzed glycosylation of sterically-hindered precursors

Chemical communications (Cambridge, England), 2017-05, Vol.53 (43), p.5838-5841

2017

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Synthesis of Readily Modifiable Cyclodextrin Analogues via Cyclodimerization of an Alkynyl−Azido Trisaccharide

Journal of the American Chemical Society, 2004-02, Vol.126 (6), p.1638-1639

2004

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Development of a minimal saponin vaccine adjuvant based on QS-21

Nature chemistry, 2014-07, Vol.6 (7), p.635

2014

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Versatile strategy for the divergent synthesis of linear oligosaccharide domain variants of Quillaja saponin vaccine adjuvants

Chemical communications (Cambridge, England), 2015-09, Vol.51 (73), p.13949-13952

2015

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Quillaja Saponin Variants with Central Glycosidic Linkage Modifications Exhibit Distinct Conformations and Adjuvant Activities

Chemical science (Cambridge), 2016-03, Vol.7 (3), p.2371-2380

2016

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Non-natural and photo-reactive amino acids as biochemical probes of immune function

PloS one, 2008-12, Vol.3 (12), p.e3938-e3938

2008

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Highly convergent synthesis of C3- or C2-symmetric carbohydrate macrocycles

Organic letters, 2005-09, Vol.7 (20), p.4479-4482

2005

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Correction: Versatile strategy for the divergent synthesis of linear oligosaccharide domain variants of Quillaja saponin vaccine adjuvants

Chemical communications (Cambridge, England), 2015-10, Vol.51 (76), p.1441-1441

2015

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Ring-Opening of Aziridine-2-Carboxamides with Carbohydrate C1-O-Nucleophiles. Stereoselective Preparation of α- and β-O-Glycosyl Serine Conjugates

Journal of the American Chemical Society, 2008-11, Vol.130 (46), p.15228-15229

2008

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Cell-selective labeling using amino acid precursors for proteomic studies of multicellular environments

Nature methods, 2013-08, Vol.10 (8), p.768

2013

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Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol

Bioorganic & medicinal chemistry, 2014-11, Vol.22 (21), p.5917-5923

2014

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Highly Convergent Synthesis of C 3- or C 2-Symmetric Carbohydrate Macrocycles

Organic letters, 2005-09, Vol.7 (20), p.4479-4482

2005

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Dehydrative Glycosylation with Activated Diphenyl Sulfonium Reagents. Scope, Mode of C(1)-Hemiacetal Activation, and Detection of Reactive Glycosyl Intermediates

Journal of the American Chemical Society, 2000-05, Vol.122 (18), p.4269-4279

2000

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Synthesis and Structure Verification of the Vaccine Adjuvant QS-7-Api. Synthetic Access to Homogeneous Quillaja saponaria Immunostimulants

Journal of the American Chemical Society, 2008-05, Vol.130 (18), p.5860-5861

2008

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Synthetic Access to the Chlorocyclopentane Cores of the Proposed Original and Revised Structures of Palau'amine

Angewandte Chemie (International ed.), 2008-01, Vol.47 (36), p.6821-6824

2008

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Total Synthesis of (+)-Batzelladine A and (−)-Batzelladine D via [4 + 2]-Annulation of Vinyl Carbodiimides with N-Alkyl Imines

Journal of the American Chemical Society, 2006-10, Vol.128 (40), p.13255-13260

2006

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Preclinical evaluation of the synthetic adjuvant SQS-21 and its constituent isomeric saponins

Vaccine, 2010-06, Vol.28 (26), p.4260-4267

2010

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Dehydrative Sialylation with C2-Hemiketal Sialyl Donors

Organic letters, 2003-07, Vol.5 (14), p.2539-2541

2003

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C2-Hydroxyglycosylation with Glycal Donors. Probing the Mechanism of Sulfonium-Mediated Oxygen Transfer to Glycal Enol Ethers

Journal of the American Chemical Society, 2002-06, Vol.124 (25), p.7343-7352

2002

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Site-Selective Conjugation of Thiols with Aziridine-2-Carboxylic Acid-Containing Peptides

Journal of the American Chemical Society, 2004-10, Vol.126 (40), p.12712-12713

2004

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Synthesis of QS-21-Xylose: Establishment of the Immunopotentiating Activity of Synthetic QS-21 Adjuvant with a Melanoma Vaccine

Development of Improved Vaccine Adjuvants Based on the Saponin Natural Product QS-21 through Chemical Synthesis

Synthesis of Antiproliferative Cephalotaxus Esters and Their Evaluation against Several Human Hematopoietic and Solid Tumor Cell Lines: Uncovering Differential Susceptibilities to Multidrug Resistance

Natural and synthetic saponin adjuvant QS-21 for vaccines against cancer

Synthesis of the hexacyclic triterpene core of the jujuboside saponins via tandem Wolff rearrangement–intramolecular ketene hetero-Diels–Alder reaction

Rapid assembly of the doubly-branched pentasaccharide domain of the immunoadjuvant jujuboside A via convergent B(C 6 F 5 ) 3 -catalyzed glycosylation of sterically-hindered precursors

Synthesis of Readily Modifiable Cyclodextrin Analogues via Cyclodimerization of an Alkynyl−Azido Trisaccharide

Development of a minimal saponin vaccine adjuvant based on QS-21

Versatile strategy for the divergent synthesis of linear oligosaccharide domain variants of Quillaja saponin vaccine adjuvants

Quillaja Saponin Variants with Central Glycosidic Linkage Modifications Exhibit Distinct Conformations and Adjuvant Activities

Non-natural and photo-reactive amino acids as biochemical probes of immune function

Highly convergent synthesis of C3- or C2-symmetric carbohydrate macrocycles

Correction: Versatile strategy for the divergent synthesis of linear oligosaccharide domain variants of Quillaja saponin vaccine adjuvants

Ring-Opening of Aziridine-2-Carboxamides with Carbohydrate C1-O-Nucleophiles. Stereoselective Preparation of α- and β-O-Glycosyl Serine Conjugates

Cell-selective labeling using amino acid precursors for proteomic studies of multicellular environments

Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol

Highly Convergent Synthesis of C 3- or C 2-Symmetric Carbohydrate Macrocycles

Dehydrative Glycosylation with Activated Diphenyl Sulfonium Reagents. Scope, Mode of C(1)-Hemiacetal Activation, and Detection of Reactive Glycosyl Intermediates

Synthesis and Structure Verification of the Vaccine Adjuvant QS-7-Api. Synthetic Access to Homogeneous Quillaja saponaria Immunostimulants

Synthetic Access to the Chlorocyclopentane Cores of the Proposed Original and Revised Structures of Palau'amine

Total Synthesis of (+)-Batzelladine A and (−)-Batzelladine D via [4 + 2]-Annulation of Vinyl Carbodiimides with N-Alkyl Imines

Preclinical evaluation of the synthetic adjuvant SQS-21 and its constituent isomeric saponins

Dehydrative Sialylation with C2-Hemiketal Sialyl Donors

C2-Hydroxyglycosylation with Glycal Donors. Probing the Mechanism of Sulfonium-Mediated Oxygen Transfer to Glycal Enol Ethers

Site-Selective Conjugation of Thiols with Aziridine-2-Carboxylic Acid-Containing Peptides

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