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HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4

Journal of allergy and clinical immunology, 2017-08, Vol.140 (2), p.584-587.e8

2017

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GRK2 expression and catalytic activity are essential for vasoconstrictor/ERK-stimulated arterial smooth muscle proliferation

Biochemical pharmacology, 2023-10, Vol.216, p.115795-115795, Article 115795

2023

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Using the Flp-In™ T-Rex™ system to regulate GPCR expression

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.21

2011

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G protein-coupled receptor signalling in astrocytes in health and disease: A focus on metabotropic glutamate receptors

Biochemical pharmacology, 2012-08, Vol.84 (3), p.249-259

2012

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Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors

Biochemical journal, 2001-11, Vol.359 (Pt 3), p.465-484

2001

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Differential regulation of β2-adrenoceptor and adenosine A2B receptor signalling by GRK and arrestin proteins in arterial smooth muscle

Cellular signalling, 2018-11, Vol.51, p.86-98

2018

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Design and use of fluorescent ligands to study ligand-receptor interactions in single living cells

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.211

2011

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Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2

Cardiovascular research, 2010-02, Vol.85 (3), p.424-433

2010

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Study of GPCR-protein interactions by BRET

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.357

2011

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Time resolved FRET strategy with fluorescent ligands to analyze receptor interactions in native tissues: application to GPCR oligomerization

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.373

2011

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Measuring spatiotemporal dynamics of cyclic AMP signaling in real-time using FRET-based biosensors

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.297

2011

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Radioligand binding methods for membrane preparations and intact cells

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.135

2011

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A model for Ca2+ oscillations stimulated by the type 5 metabotropic glutamate receptor: an unusual mechanism based on repetitive, reversible phosphorylation of the receptor

Biochimie, 2011-12, Vol.93 (12), p.2132-2138

2011

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G protein-coupled receptor kinase 2 and arrestin2 regulate arterial smooth muscle P2Y-purinoceptor signalling

Cardiovascular research, 2011-01, Vol.89 (1), p.193-203

2011

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Determining allosteric modulator mechanism of action: integration of radioligand binding and functional assay data

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.195

Langmead, Christopher J

2011

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Principal role of adenylyl cyclase 6 in K+ channel regulation and vasodilator signalling in vascular smooth muscle cells

Cardiovascular research, 2011-09, Vol.91 (4), p.694-702

2011

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Regulation of neuronal plasticity and fear by a dynamic change in PAR1―G protein coupling in the amygdala

Molecular psychiatry, 2013-10, Vol.18 (10), p.1136-1145

2013

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[Ca2+]i oscillations in ASM: Relationship with persistent airflow obstruction in asthma

Respirology (Carlton, Vic.), 2014-07, Vol.19 (5), p.763-766

2014

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Identification of GPCR localization in detergent resistant membranes

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.411

2011

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Using calcium imaging as a readout of GPCR activation

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.277

2011

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Temporal profiling of changes in phosphatidylinositol 4,5-bisphosphate, inositol 1,4,5-trisphosphate and diacylglycerol allows comprehensive analysis of phospholipase C-initiated signalling in single neurons

Journal of neurochemistry, 2008-11, Vol.107 (3), p.602-615

2008

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Generation of epitope-tagged GPCRs

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.53

2011

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Quantification of GPCR mRNA using real-time RT-PCR

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.165

2011

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Examining site-specific GPCR phosphorylation

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.237

2011

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Ubiquitination of GPCRs

Methods in molecular biology (Clifton, N.J.), 2011, Vol.746, p.251

2011

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HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4

GRK2 expression and catalytic activity are essential for vasoconstrictor/ERK-stimulated arterial smooth muscle proliferation

Using the Flp-In™ T-Rex™ system to regulate GPCR expression

G protein-coupled receptor signalling in astrocytes in health and disease: A focus on metabotropic glutamate receptors

Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors

Differential regulation of β2-adrenoceptor and adenosine A2B receptor signalling by GRK and arrestin proteins in arterial smooth muscle

Design and use of fluorescent ligands to study ligand-receptor interactions in single living cells

Endothelin signalling in arterial smooth muscle is tightly regulated by G protein-coupled receptor kinase 2

Study of GPCR-protein interactions by BRET

Time resolved FRET strategy with fluorescent ligands to analyze receptor interactions in native tissues: application to GPCR oligomerization

Measuring spatiotemporal dynamics of cyclic AMP signaling in real-time using FRET-based biosensors

Radioligand binding methods for membrane preparations and intact cells

A model for Ca2+ oscillations stimulated by the type 5 metabotropic glutamate receptor: an unusual mechanism based on repetitive, reversible phosphorylation of the receptor

G protein-coupled receptor kinase 2 and arrestin2 regulate arterial smooth muscle P2Y-purinoceptor signalling

Determining allosteric modulator mechanism of action: integration of radioligand binding and functional assay data

Principal role of adenylyl cyclase 6 in K+ channel regulation and vasodilator signalling in vascular smooth muscle cells

Regulation of neuronal plasticity and fear by a dynamic change in PAR1―G protein coupling in the amygdala

[Ca2+]i oscillations in ASM: Relationship with persistent airflow obstruction in asthma

Identification of GPCR localization in detergent resistant membranes

Using calcium imaging as a readout of GPCR activation

Temporal profiling of changes in phosphatidylinositol 4,5-bisphosphate, inositol 1,4,5-trisphosphate and diacylglycerol allows comprehensive analysis of phospholipase C-initiated signalling in single neurons

Generation of epitope-tagged GPCRs

Quantification of GPCR mRNA using real-time RT-PCR

Examining site-specific GPCR phosphorylation

Ubiquitination of GPCRs

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