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Tyrosine 547 Constitutes an Essential Part of the Catalytic Mechanism of Dipeptidyl Peptidase IV

The Journal of biological chemistry, 2004-08, Vol.279 (33), p.34691-34697

2004

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Structure Determination of T Cell Protein-tyrosine Phosphatase

The Journal of biological chemistry, 2002-05, Vol.277 (22), p.19982-19990

2002

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Discovery and SAR of a Novel Selective and Orally Bioavailable Nonpeptide Classical Competitive Inhibitor Class of Protein-Tyrosine Phosphatase 1B

Journal of medicinal chemistry, 2002-09, Vol.45 (20), p.4443-4459

2002

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Structure-based Design of a Low Molecular Weight, Nonphosphorus, Nonpeptide, and Highly Selective Inhibitor of Protein-tyrosine Phosphatase 1B

The Journal of biological chemistry, 2000-04, Vol.275 (14), p.10300-10307

2000

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2-(Oxalylamino)-Benzoic Acid Is a General, Competitive Inhibitor of Protein-tyrosine Phosphatases

The Journal of biological chemistry, 2000-03, Vol.275 (10), p.7101-7108

2000

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Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog

Nature structural & molecular biology, 2003-01, Vol.10 (1), p.19-25

2003

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Enzyme kinetic characterization of protein tyrosine phosphatases

Biochimie, 2003-05, Vol.85 (5), p.527-534

2003

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Crystal structure of the alkaline proteinase Savinase ™ from Bacillus lentus at 1.4 Å resolution

Journal of molecular biology, 1992-01, Vol.223 (2), p.427-445

1992

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Affinity purification of recombinant protein-tyrosine phosphatase 1B using a highly selective inhibitor

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2004-01, Vol.799 (1), p.1-8

2004

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Dipeptidyl peptidases 8 and 9: specificity and molecular characterization compared with dipeptidyl peptidase IV

Biochemical journal, 2006-06, Vol.396 (2), p.391-399

2006

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Characterization of recombinant murine factor VIIa and recombinant murine tissue factor: a human–murine species compatibility study

Thrombosis research, 2005, Vol.116 (1), p.75-85

2005

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Steric Hindrance as a Basis for Structure-Based Design of Selective Inhibitors of Protein-Tyrosine Phosphatases

Biochemistry (Easton), 2001-12, Vol.40 (49), p.14812-14820

2001

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Dipeptidyl peptidase 8 and 9: specificity and molecular characterization compared to dipeptidyl peptidase IV

Biochemical journal, 2006-02, Vol.396 (2), p.391-399

2006

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Residue 259 Is a Key Determinant of Substrate Specificity of Protein-tyrosine Phosphatases 1B and α

The Journal of biological chemistry, 2000-06, Vol.275 (24), p.18201-18209

2000

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Synthesis of 2-amino-4h-thiazolo[5,4-b]indole and characterization of its colored conversion products with protein tyrosine phosphatase inhibitory activity

Journal of heterocyclic chemistry, 2001-05, Vol.38 (3), p.569-577

2001

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Cavity Mutants of Savinase™: Crystal Structures and Differential Scanning Calorimetry Experiments Give Hints of the Function of the Buried Water Molecules in Subtilisins

Journal of molecular biology, 1994-09, Vol.242 (3), p.193-202

1994

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Residue 259 Is a Key Determinant of Substrate Specificity of Protein-tyrosine Phosphatases 1B and Î

The Journal of biological chemistry, 2000-06, Vol.275 (24), p.18201

2000

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Synthesis of 2‐amino‐4 h ‐thiazolo[5,4‐ b ]indole and characterization of its colored conversion products with protein tyrosine phosphatase inhibitory activity

Journal of heterocyclic chemistry, 2001-05, Vol.38 (3), p.569-577

2001

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Crystal structures of the alkaline proteases savinase and esperase from Bacillus lentus

Advances in experimental medicine and biology, 1996, Vol.379, p.49

1996

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pH dependence of the catalytic activity of a subtilisin-like proteinase

Advances in experimental medicine and biology, 1996, Vol.379, p.229

1996

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Cavity Mutants of Savinase

Journal of molecular biology, 1994-09, Vol.242 (3), p.193-202

1994

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An investigation of the savinase water channel: implications of cavity mutations

Advances in experimental medicine and biology, 1996, Vol.379, p.235

1996

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X-Ray structure of the antibiotic bacitracin A

FEBS letters, 1991-07, Vol.285 (1), p.115-119

1991

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Engineering surface charges in a subtilisin: the effects on electrophoretic and ion-exchange behaviour

Protein engineering, 1994-06, Vol.7 (6), p.793-800

1994

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Crystallographic Studies of Savinase, a Subtilisin‐like Proteinase, at pH 10.5

European journal of biochemistry, 1994-09, Vol.224 (2), p.507-518

1994

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Tyrosine 547 Constitutes an Essential Part of the Catalytic Mechanism of Dipeptidyl Peptidase IV

Structure Determination of T Cell Protein-tyrosine Phosphatase

Discovery and SAR of a Novel Selective and Orally Bioavailable Nonpeptide Classical Competitive Inhibitor Class of Protein-Tyrosine Phosphatase 1B

Structure-based Design of a Low Molecular Weight, Nonphosphorus, Nonpeptide, and Highly Selective Inhibitor of Protein-tyrosine Phosphatase 1B

2-(Oxalylamino)-Benzoic Acid Is a General, Competitive Inhibitor of Protein-tyrosine Phosphatases

Crystal structure of human dipeptidyl peptidase IV/CD26 in complex with a substrate analog

Enzyme kinetic characterization of protein tyrosine phosphatases

Crystal structure of the alkaline proteinase Savinase ™ from Bacillus lentus at 1.4 Å resolution

Affinity purification of recombinant protein-tyrosine phosphatase 1B using a highly selective inhibitor

Dipeptidyl peptidases 8 and 9: specificity and molecular characterization compared with dipeptidyl peptidase IV

Characterization of recombinant murine factor VIIa and recombinant murine tissue factor: a human–murine species compatibility study

Steric Hindrance as a Basis for Structure-Based Design of Selective Inhibitors of Protein-Tyrosine Phosphatases

Dipeptidyl peptidase 8 and 9: specificity and molecular characterization compared to dipeptidyl peptidase IV

Residue 259 Is a Key Determinant of Substrate Specificity of Protein-tyrosine Phosphatases 1B and α

Synthesis of 2-amino-4h-thiazolo[5,4-b]indole and characterization of its colored conversion products with protein tyrosine phosphatase inhibitory activity

Cavity Mutants of Savinase™: Crystal Structures and Differential Scanning Calorimetry Experiments Give Hints of the Function of the Buried Water Molecules in Subtilisins

Residue 259 Is a Key Determinant of Substrate Specificity of Protein-tyrosine Phosphatases 1B and Î

Synthesis of 2‐amino‐4 h ‐thiazolo[5,4‐ b ]indole and characterization of its colored conversion products with protein tyrosine phosphatase inhibitory activity

Crystal structures of the alkaline proteases savinase and esperase from Bacillus lentus

pH dependence of the catalytic activity of a subtilisin-like proteinase

Cavity Mutants of Savinase

An investigation of the savinase water channel: implications of cavity mutations

X-Ray structure of the antibiotic bacitracin A

Engineering surface charges in a subtilisin: the effects on electrophoretic and ion-exchange behaviour

Crystallographic Studies of Savinase, a Subtilisin‐like Proteinase, at pH 10.5

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