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Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2

Science (American Association for the Advancement of Science), 1999-12, Vol.286 (5449), p.2495-2498

1999

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β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3

Science (American Association for the Advancement of Science), 2000-11, Vol.290 (5496), p.1574-1577

2000

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Platelet-Derived Growth Factor Receptor Association with Na+/H+ Exchanger Regulatory Factor Potentiates Receptor Activity

Molecular and Cellular Biology, 2000-11, Vol.20 (22), p.8352-8363

2000

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Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor

Science (American Association for the Advancement of Science), 1995-06, Vol.268 (5215), p.1350-1353

1995

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Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases

The Journal of biological chemistry, 1999-05, Vol.274 (20), p.13978-13984

1999

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Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases

The Journal of biological chemistry, 1994-03, Vol.269 (9), p.6832-6841

1994

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Turning off the signal: desensitization of β‐adrenergic receptor function

The FASEB journal, 1990-08, Vol.4 (11), p.2881-2889

1990

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β-Arrestin Scaffolding of the ERK Cascade Enhances Cytosolic ERK Activity but Inhibits ERK-mediated Transcription following Angiotensin AT1a Receptor Stimulation

The Journal of biological chemistry, 2002-03, Vol.277 (11), p.9429-9436

2002

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Dishevelled 2 Recruits β-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4

Science (American Association for the Advancement of Science), 2003-09, Vol.301 (5638), p.1391-1394

2003

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Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors

Annual review of pharmacology and toxicology, 2012-01, Vol.52 (1), p.179-197

2012

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Desensitization, Internalization, and Signaling Functions of β-Arrestins Demonstrated by RNA Interference

Proceedings of the National Academy of Sciences - PNAS, 2003-02, Vol.100 (4), p.1740-1744

2003

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Activation and Targeting of Extracellular Signal-Regulated Kinases by β-Arrestin Scaffolds

Proceedings of the National Academy of Sciences - PNAS, 2001-02, Vol.98 (5), p.2449-2454

2001

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β -adrenergic Receptor Kinase: Identification of a Novel Protein Kinase That Phosphorylates the Agonist-Occupied Form of the Receptor

Proceedings of the National Academy of Sciences - PNAS, 1986-05, Vol.83 (9), p.2797-2801

1986

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The G-Protein-Coupled Receptor Phosphatase: A Protein Phosphatase Type 2A with a Distinct Subcellular Distribution and Substrate Specificity

Proceedings of the National Academy of Sciences - PNAS, 1995-08, Vol.92 (18), p.8343-8347

1995

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In vivo inhibition of elevated myocardial β-adrenergic receptor kinase activity in hybrid transgenic mice restores normal β-adrenergic signaling and function

Circulation (New York, N.Y.), 1999-08, Vol.100 (6), p.648-653

1999

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Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems

The Journal of biological chemistry, 1992-04, Vol.267 (12), p.8558-8564

1992

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The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2

The Journal of biological chemistry, 1993-05, Vol.268 (13), p.9161-9164

1993

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The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor

The Journal of biological chemistry, 2000-03, Vol.275 (13), p.9572-9580

2000

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Protein Kinase A and G Protein-coupled Receptor Kinase Phosphorylation Mediates β-1 Adrenergic Receptor Endocytosis through Different Pathways

The Journal of biological chemistry, 2003-09, Vol.278 (37), p.35403-35411

2003

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Molecular mechanisms of receptor desensitization using the β -adrenergic receptor-coupled adenylate cyclase system as a model

Nature (London), 1985-09, Vol.317 (6033), p.124-129

1985

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Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation

Nature (London), 1987-05, Vol.327 (6117), p.67-70

1987

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Phosphorylation/Dephosphorylation of the β -adrenergic Receptor Regulates Its Functional Coupling to Adenylate Cyclase and Subcellular Distribution

Proceedings of the National Academy of Sciences - PNAS, 1986-12, Vol.83 (24), p.9408-9412

1986

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Role of acidic amino acids in peptide substrates of the .beta.-adrenergic receptor kinase and rhodopsin kinase

Biochemistry (Easton), 1991-05, Vol.30 (21), p.5118-5125

1991

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β-Arrestins Regulate Mitogenic Signaling and Clathrin-mediated Endocytosis of the Insulin-like Growth Factor I Receptor

The Journal of biological chemistry, 1998-11, Vol.273 (48), p.31640-31643

1998

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Assembly of an A kinase-anchoring protein-beta(2)-adrenergic receptor complex facilitates receptor phosphorylation and signaling

Current biology, 2000-04, Vol.10 (7), p.409-412

2000

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Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2

β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3

Platelet-Derived Growth Factor Receptor Association with Na+/H+ Exchanger Regulatory Factor Potentiates Receptor Activity

Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor

Pleiotropic coupling of G protein-coupled receptors to the mitogen-activated protein kinase cascade. Role of focal adhesions and receptor tyrosine kinases

Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases

Turning off the signal: desensitization of β‐adrenergic receptor function

β-Arrestin Scaffolding of the ERK Cascade Enhances Cytosolic ERK Activity but Inhibits ERK-mediated Transcription following Angiotensin AT1a Receptor Stimulation

Dishevelled 2 Recruits β-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4

Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors

Desensitization, Internalization, and Signaling Functions of β-Arrestins Demonstrated by RNA Interference

Activation and Targeting of Extracellular Signal-Regulated Kinases by β-Arrestin Scaffolds

β -adrenergic Receptor Kinase: Identification of a Novel Protein Kinase That Phosphorylates the Agonist-Occupied Form of the Receptor

The G-Protein-Coupled Receptor Phosphatase: A Protein Phosphatase Type 2A with a Distinct Subcellular Distribution and Substrate Specificity

In vivo inhibition of elevated myocardial β-adrenergic receptor kinase activity in hybrid transgenic mice restores normal β-adrenergic signaling and function

Receptor-specific desensitization with purified proteins. Kinase dependence and receptor specificity of beta-arrestin and arrestin in the beta 2-adrenergic receptor and rhodopsin systems

The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2

The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor

Protein Kinase A and G Protein-coupled Receptor Kinase Phosphorylation Mediates β-1 Adrenergic Receptor Endocytosis through Different Pathways

Molecular mechanisms of receptor desensitization using the β -adrenergic receptor-coupled adenylate cyclase system as a model

Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation

Phosphorylation/Dephosphorylation of the β -adrenergic Receptor Regulates Its Functional Coupling to Adenylate Cyclase and Subcellular Distribution

Role of acidic amino acids in peptide substrates of the .beta.-adrenergic receptor kinase and rhodopsin kinase

β-Arrestins Regulate Mitogenic Signaling and Clathrin-mediated Endocytosis of the Insulin-like Growth Factor I Receptor

Assembly of an A kinase-anchoring protein-beta(2)-adrenergic receptor complex facilitates receptor phosphorylation and signaling

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