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Programmed Death-1 Inhibition of Phosphatidylinositol 3-Kinase/AKT/Mechanistic Target of Rapamycin Signaling Impairs Sarcoidosis CD4 + T Cell Proliferation

American journal of respiratory cell and molecular biology, 2017-01, Vol.56 (1), p.74-82

2017

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Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α

Genes & development, 2014-12, Vol.28 (23), p.2621-2635

2014

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Endosomal cargo recycling mediated by Gpa1 and phosphatidylinositol 3-kinase is inhibited by glucose starvation

Molecular biology of the cell, 2022-04, Vol.33 (4), p.ar31-ar31

2022

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class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagy

The Journal of cell biology, 2010-11, Vol.191 (4), p.827-843

2010

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Cracking the context-specific PI3K signaling code

Science signaling, 2020-01, Vol.13 (613)

2020

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TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α

Science signaling, 2017-07, Vol.10 (486)

2017

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Par3 integrates Tiam1 and phosphatidylinositol 3-kinase signaling to change apical membrane identity

Molecular biology of the cell, 2017-01, Vol.28 (2), p.252-260

2017

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Tyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration

Science signaling, 2011-09, Vol.4 (192), p.ra64

2011

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CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation

The Journal of cell biology, 2021-09, Vol.220 (9), p.1

2021

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A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1-mediated adhesion in T cells

Science signaling, 2022-07, Vol.15 (743), p.eabl9169

2022

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Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis

Molecular biology of the cell, 2012-12, Vol.23 (23), p.4526-4542

2012

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Essentiality of Sis1, a J-domain protein Hsp70 cochaperone, can be overcome by Tti1, a specialized PIKK chaperone

Molecular biology of the cell, 2022-03, Vol.33 (3), p.br3-br3

2022

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Staying alive: Metabolic adaptations to quiescence

Cell cycle (Georgetown, Tex.), 2012-05, Vol.11 (9), p.1680-1696

2012

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A module for Rac temporal signal integration revealed with optogenetics

The Journal of cell biology, 2017-08, Vol.216 (8), p.2515-2531

2017

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Propranolol improves impaired hepatic phosphatidylinositol 3-kinase/akt signaling after burn injury

Molecular medicine (Cambridge, Mass.), 2012-05, Vol.18 (4), p.707-711

2012

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PI3Kβ plays a critical role in neutrophil activation by immune complexes

Science signaling, 2011-04, Vol.4 (168), p.ra23

2011

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Phosphoinositide‐3 kinase gamma regulates caspase‐1 activation and leukocyte recruitment in acute murine gout

Journal of leukocyte biology, 2019-09, Vol.106 (3), p.619-629

2019

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Phosphoinositide 3-kinase γ inhibits cardiac GSK-3 independently of Akt

Science signaling, 2013-01, Vol.6 (259), p.ra4

2013

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PI3Kβ links integrin activation and PI(3,4)P 2 production during invadopodial maturation

Molecular biology of the cell, 2019-08, Vol.30 (18), p.2367-2376

2019

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miR-451 suppresses EMT and metastasis in glioma cells

Cell cycle (Georgetown, Tex.), 2021-07, Vol.20 (13), p.1270-1278

2021

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α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion

The Journal of cell biology, 2017-11, Vol.216 (11), p.3767-3783

2017

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Molecular insights into kinase mediated signaling pathways of chemokines and their cognate G protein coupled receptors

Frontiers in bioscience (Landmark. Print), 2020-03, Vol.25 (7), p.1361-1385

2020

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Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids

Nature medicine, 2014-02, Vol.20 (2), p.175-183

2014

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TGF-β is associated with poor prognosis and promotes osteosarcoma progression via PI3K/Akt pathway activation

Cell cycle (Georgetown, Tex.), 2020-09, Vol.19 (18), p.2327-2339

2020

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p85β increases phosphoinositide 3-kinase activity and accelerates tumor progression

Cell cycle (Georgetown, Tex.), 2012-10, Vol.11 (19), p.3523-3524

2012

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Programmed Death-1 Inhibition of Phosphatidylinositol 3-Kinase/AKT/Mechanistic Target of Rapamycin Signaling Impairs Sarcoidosis CD4 + T Cell Proliferation

Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α

Endosomal cargo recycling mediated by Gpa1 and phosphatidylinositol 3-kinase is inhibited by glucose starvation

class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagy

Cracking the context-specific PI3K signaling code

TGF-β promotes PI3K-AKT signaling and prostate cancer cell migration through the TRAF6-mediated ubiquitylation of p85α

Par3 integrates Tiam1 and phosphatidylinositol 3-kinase signaling to change apical membrane identity

Tyrosine phosphorylation of the Gα-interacting protein GIV promotes activation of phosphoinositide 3-kinase during cell migration

CYRI-A limits invasive migration through macropinosome formation and integrin uptake regulation

A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1-mediated adhesion in T cells

Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis

Essentiality of Sis1, a J-domain protein Hsp70 cochaperone, can be overcome by Tti1, a specialized PIKK chaperone

Staying alive: Metabolic adaptations to quiescence

A module for Rac temporal signal integration revealed with optogenetics

Propranolol improves impaired hepatic phosphatidylinositol 3-kinase/akt signaling after burn injury

PI3Kβ plays a critical role in neutrophil activation by immune complexes

Phosphoinositide‐3 kinase gamma regulates caspase‐1 activation and leukocyte recruitment in acute murine gout

Phosphoinositide 3-kinase γ inhibits cardiac GSK-3 independently of Akt

PI3Kβ links integrin activation and PI(3,4)P 2 production during invadopodial maturation

miR-451 suppresses EMT and metastasis in glioma cells

α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion

Molecular insights into kinase mediated signaling pathways of chemokines and their cognate G protein coupled receptors

Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids

TGF-β is associated with poor prognosis and promotes osteosarcoma progression via PI3K/Akt pathway activation

p85β increases phosphoinositide 3-kinase activity and accelerates tumor progression

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