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Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2

Science (American Association for the Advancement of Science), 1999-12, Vol.286 (5449), p.2495-2498

1999

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β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3

Science (American Association for the Advancement of Science), 2000-11, Vol.290 (5496), p.1574-1577

2000

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G protein—coupled receptor kinases

Cell, 1993-08, Vol.74 (3), p.409-412

Lefkowitz, Robert J.

1993

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Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor

Science (American Association for the Advancement of Science), 1995-06, Vol.268 (5215), p.1350-1353

1995

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Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by β-adrenergic receptor stimulation and blockade

Circulation (New York, N.Y.), 1998-10, Vol.98 (17), p.1783-1789

1998

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Beta-adrenergic receptor sequestration. A potential mechanism of receptor resensitization

The Journal of biological chemistry, 1993-01, Vol.268 (1), p.337-341

1993

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Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family

The Journal of biological chemistry, 1992-09, Vol.267 (25), p.17882-17890

1992

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Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases

The Journal of biological chemistry, 1994-03, Vol.269 (9), p.6832-6841

1994

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Turning off the signal: desensitization of β‐adrenergic receptor function

The FASEB journal, 1990-08, Vol.4 (11), p.2881-2889

1990

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μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence

Nature (London), 2000-12, Vol.408 (6813), p.720-723

2000

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Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors

Annual review of pharmacology and toxicology, 2012-01, Vol.52 (1), p.179-197

2012

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Dishevelled 2 Recruits β-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4

Science (American Association for the Advancement of Science), 2003-09, Vol.301 (5638), p.1391-1394

2003

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β -adrenergic Receptor Kinase: Identification of a Novel Protein Kinase That Phosphorylates the Agonist-Occupied Form of the Receptor

Proceedings of the National Academy of Sciences - PNAS, 1986-05, Vol.83 (9), p.2797-2801

1986

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In vivo inhibition of elevated myocardial β-adrenergic receptor kinase activity in hybrid transgenic mice restores normal β-adrenergic signaling and function

Circulation (New York, N.Y.), 1999-08, Vol.100 (6), p.648-653

1999

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The Receptor Kinase Family: Primary Structure of Rhodopsin Kinase Reveals Similarities to the β-Adrenergic Receptor Kinase

Proceedings of the National Academy of Sciences - PNAS, 1991-10, Vol.88 (19), p.8715-8719

1991

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The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain

The Journal of neuroscience, 1992-10, Vol.12 (10), p.4045-4055

1992

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Structure of the adrenergic and related receptors

Annual review of neuroscience, 1989-01, Vol.12 (1), p.67-83

1989

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The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2

The Journal of biological chemistry, 1993-05, Vol.268 (13), p.9161-9164

1993

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The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor

Nature (London), 1988-09, Vol.335 (6188), p.358-360

1988

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Prospects for cardiovascular research

JAMA : the journal of the American Medical Association, 2001-02, Vol.285 (5), p.581

2001

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Molecular mechanisms of receptor desensitization using the β -adrenergic receptor-coupled adenylate cyclase system as a model

Nature (London), 1985-09, Vol.317 (6033), p.124-129

1985

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Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation

Nature (London), 1987-05, Vol.327 (6117), p.67-70

1987

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In vivo ventricular gene delivery of a β-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction

Circulation (New York, N.Y.), 2001-03, Vol.103 (9), p.1311-1316

2001

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Phosphorylation/Dephosphorylation of the β -adrenergic Receptor Regulates Its Functional Coupling to Adenylate Cyclase and Subcellular Distribution

Proceedings of the National Academy of Sciences - PNAS, 1986-12, Vol.83 (24), p.9408-9412

1986

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Role of acidic amino acids in peptide substrates of the .beta.-adrenergic receptor kinase and rhodopsin kinase

Biochemistry (Easton), 1991-05, Vol.30 (21), p.5118-5125

1991

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Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2

β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3

G protein—coupled receptor kinases

Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor

Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by β-adrenergic receptor stimulation and blockade

Beta-adrenergic receptor sequestration. A potential mechanism of receptor resensitization

Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family

Identification, purification, and characterization of GRK5, a member of the family of G protein-coupled receptor kinases

Turning off the signal: desensitization of β‐adrenergic receptor function

μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence

Molecular Mechanism of β-Arrestin-Biased Agonism at Seven-Transmembrane Receptors

Dishevelled 2 Recruits β-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4

β -adrenergic Receptor Kinase: Identification of a Novel Protein Kinase That Phosphorylates the Agonist-Occupied Form of the Receptor

In vivo inhibition of elevated myocardial β-adrenergic receptor kinase activity in hybrid transgenic mice restores normal β-adrenergic signaling and function

The Receptor Kinase Family: Primary Structure of Rhodopsin Kinase Reveals Similarities to the β-Adrenergic Receptor Kinase

The G-protein-coupled receptor kinases beta ARK1 and beta ARK2 are widely distributed at synapses in rat brain

Structure of the adrenergic and related receptors

The substance P receptor, which couples to Gq/11, is a substrate of beta-adrenergic receptor kinase 1 and 2

The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor

Prospects for cardiovascular research

Molecular mechanisms of receptor desensitization using the β -adrenergic receptor-coupled adenylate cyclase system as a model

Cross-talk between cellular signalling pathways suggested by phorbol-ester-induced adenylate cyclase phosphorylation

In vivo ventricular gene delivery of a β-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction

Phosphorylation/Dephosphorylation of the β -adrenergic Receptor Regulates Its Functional Coupling to Adenylate Cyclase and Subcellular Distribution

Role of acidic amino acids in peptide substrates of the .beta.-adrenergic receptor kinase and rhodopsin kinase

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