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Present status and future perspectives of drug delivery field

Drug delivery system, 1999, Vol.14 (2), p.73-78

Sezaki, Hitoshi

1999

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Therapeutic effects of superoxide dismutase derivatives modified with mono- or polysaccharides on hepatic injury induced by ischemia/reperfusion

Biochemical and biophysical research communications, 1992-11, Vol.189 (1), p.191-196

1992

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Soluble macromolecular carriers for the delivery of antitumour drugs

Advanced drug delivery reviews, 1989-03, Vol.3 (2), p.247-266

1989

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Structure-activity relationship of 1-alkyl- or 1-alkenylazacycloalkanone derivatives as percutaneous penetration enhancers

Journal of pharmaceutical sciences, 1988-05, Vol.77 (5), p.418-424

1988

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Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. II. Disposition and pharmacokinetics following intravenous and intramuscular administration

International journal of pharmaceutics, 1987, Vol.37 (1), p.145-154

1987

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Disposition characteristics of macromolecules in the perfused tissue-isolated tumor preparation

Cancer research (Chicago, Ill.), 1992-08, Vol.52 (16), p.4396-4401

1992

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Enhanced lymphatic delivery of mitomycin C conjugated with dextran

Cancer research (Chicago, Ill.), 1984-06, Vol.44 (6), p.2505-2510

1984

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at The Start of Our New Society

Drug delivery system, 1988, Vol.3 (3), p.381-382

Sezaki, Hitoshi

1988

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Disposition of anticancer drugs after bolus arterial administration in a tissue-isolated tumor perfusion system

Cancer research (Chicago, Ill.), 1990-03, Vol.50 (5), p.1640-1644

1990

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Our Beginning in 1983

Drug delivery system, 1993, Vol.8 (2), p.77-82

1993

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Alteration of biopharmaceutical properties of drugs by their conjugation with water-soluble macromolecules: Uricase-dextran conjugate

Journal of controlled release, 1990, Vol.11 (1), p.149-156

1990

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Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. I. Physicochemical characteristics and in vivo and in vitro antitumor activities

International journal of pharmaceutics, 1987, Vol.37 (1), p.135-143

1987

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Treatment of cystic hygroma and lymphangioma with the use of bleomycin fat emulsion

Cancer, 1987-08, Vol.60 (4), p.741-749

1987

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Analysis of skin penetration enhancement based on a two-layer skin diffusion model with polar and nonpolar routes in the stratum corneum: dose-dependent effect of 1-geranylazacycloheptan-2-one on drugs with different lipophilicities

Biological & pharmaceutical bulletin, 1993, Vol.16 (7), p.690-697

1993

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Control of Pharmaceutical Properties of Soybean Trypsin Inhibitor by Conjugation with Dextran II: Biopharmaceutical and Pharmacological Properties

Journal of pharmaceutical sciences, 1989-03, Vol.78 (3), p.219-222

1989

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Control of Pharmaceutical Properties of Soybean Trypsin Inhibitor by Conjugation with Dextran I: Synthesis and Characterization

Journal of pharmaceutical sciences, 1989-02, Vol.78 (2), p.117-121

1989

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Tissue Distribution of 111In-Labeled Uricase Conjugated with Charged Dextrans and Polyethylene Glycol

Journal of Pharmacobio-Dynamics, 1991, Vol.14(11), pp.623-629

1991

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Trends in Drug Delivery

Yakugaku zasshi, 1984, Vol.104 (12), p.1211-1222

SEZAKI, HITOSHI

1984

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Improvement of absolute bioavailability of normally poorly absorbed drugs: inducement of the intestinal absorption of streptomycin and gentamycin by lipid-bile salt mixed micelles in rat and rabbit

International journal of pharmaceutics, 1979-03, Vol.2 (2), p.101-111

1979

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Cellular interaction and in vitro antitumor activity of mitomycin C-dextran conjugate

Cancer research (Chicago, Ill.), 1986-09, Vol.46 (9), p.4463-4468

1986

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The Accumulation Mechanism of Cationic Mitomycin C-dextran Conjugates in the Liver: In-vivo Cellular Localization and In-vitro Interaction with Hepatocytes

Journal of pharmacy and pharmacology, 1988-01, Vol.40 (1), p.1-6

1988

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EFFECT OF SURFACTANTS ON THE ABSORPTION OF p-AMINOBENZOIC ACID FROM THE RAT INTESTINE

Journal of Pharmacobio-Dynamics, 1979, Vol.2(4), pp.251-256

1979

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CARRIER-MEDIATED TRANSPORT SYSTEMS FOR AMINOPENICIL-LINS IN RAT SMALL INTESTINE

Journal of Pharmacobio-Dynamics, 1978, Vol.1(4), pp.262-267

1978

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DRUG ABSORPTION FROM THE GASTROINTESTINAL TRACT AND IMMUNITY : THE MECHANISM OF THE DECREASED ABSORPTION OF SALICYLIC ACID DURING SYSTEMIC ANAPHYLAXIS.I

Journal of Pharmacobio-Dynamics, 1984, Vol.7(10), pp.728-736

1984

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Mechanism for the inducement of the intestinal absorption of poorly absorbed drugs by mixed micelles I. Effects of various lipid—bile salt mixed micelles on the intestinal absorption of streptomycin in rat

International journal of pharmaceutics, 1980, Vol.4 (4), p.271-279

1980

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Present status and future perspectives of drug delivery field

Therapeutic effects of superoxide dismutase derivatives modified with mono- or polysaccharides on hepatic injury induced by ischemia/reperfusion

Soluble macromolecular carriers for the delivery of antitumour drugs

Structure-activity relationship of 1-alkyl- or 1-alkenylazacycloalkanone derivatives as percutaneous penetration enhancers

Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. II. Disposition and pharmacokinetics following intravenous and intramuscular administration

Disposition characteristics of macromolecules in the perfused tissue-isolated tumor preparation

Enhanced lymphatic delivery of mitomycin C conjugated with dextran

at The Start of Our New Society

Disposition of anticancer drugs after bolus arterial administration in a tissue-isolated tumor perfusion system

Our Beginning in 1983

Alteration of biopharmaceutical properties of drugs by their conjugation with water-soluble macromolecules: Uricase-dextran conjugate

Development of a novel polymeric prodrug of mitomycin C, mitomycin C-dextran conjugate with anionic charge. I. Physicochemical characteristics and in vivo and in vitro antitumor activities

Treatment of cystic hygroma and lymphangioma with the use of bleomycin fat emulsion

Analysis of skin penetration enhancement based on a two-layer skin diffusion model with polar and nonpolar routes in the stratum corneum: dose-dependent effect of 1-geranylazacycloheptan-2-one on drugs with different lipophilicities

Control of Pharmaceutical Properties of Soybean Trypsin Inhibitor by Conjugation with Dextran II: Biopharmaceutical and Pharmacological Properties

Control of Pharmaceutical Properties of Soybean Trypsin Inhibitor by Conjugation with Dextran I: Synthesis and Characterization

Tissue Distribution of 111In-Labeled Uricase Conjugated with Charged Dextrans and Polyethylene Glycol

Trends in Drug Delivery

Improvement of absolute bioavailability of normally poorly absorbed drugs: inducement of the intestinal absorption of streptomycin and gentamycin by lipid-bile salt mixed micelles in rat and rabbit

Cellular interaction and in vitro antitumor activity of mitomycin C-dextran conjugate

The Accumulation Mechanism of Cationic Mitomycin C-dextran Conjugates in the Liver: In-vivo Cellular Localization and In-vitro Interaction with Hepatocytes

EFFECT OF SURFACTANTS ON THE ABSORPTION OF p-AMINOBENZOIC ACID FROM THE RAT INTESTINE

CARRIER-MEDIATED TRANSPORT SYSTEMS FOR AMINOPENICIL-LINS IN RAT SMALL INTESTINE

DRUG ABSORPTION FROM THE GASTROINTESTINAL TRACT AND IMMUNITY : THE MECHANISM OF THE DECREASED ABSORPTION OF SALICYLIC ACID DURING SYSTEMIC ANAPHYLAXIS.I

Mechanism for the inducement of the intestinal absorption of poorly absorbed drugs by mixed micelles I. Effects of various lipid—bile salt mixed micelles on the intestinal absorption of streptomycin in rat

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