UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 55

Sortiert nach

Targeting cancer with kinase inhibitors

The Journal of clinical investigation, 2015-05, Vol.125 (5), p.1780-1789

2015

Volltextzugriff (PDF)

Suppression of HER2/HER3-Mediated Growth of Breast Cancer Cells with Combinations of GDC-0941 PI3K Inhibitor, Trastuzumab, and Pertuzumab

Clinical cancer research, 2009-06, Vol.15 (12), p.4147-4156

2009

Volltextzugriff (PDF)

Phosphoproteomic characterization of DNA damage response in melanoma cells following MEK/PI3K dual inhibition

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (48), p.19426-19431

2013

Volltextzugriff (PDF)

Inhibitors of p21-activated kinases (PAKs)

Journal of medicinal chemistry, 2015-01, Vol.58 (1), p.111-129

2015

Volltextzugriff (PDF)

Active PI3K pathway causes an invasive phenotype which can be reversed or promoted by blocking the pathway at divergent nodes

PloS one, 2012-05, Vol.7 (5), p.e36402-e36402

2012

Volltextzugriff (PDF)

Evaluation of Protein Kinase cAMP-Activated Catalytic Subunit Alpha as a Therapeutic Target for Fibrolamellar Carcinoma

Gastro hep advances, 2023, Vol.2 (3), p.307-321

2023

Volltextzugriff (PDF)

Calmodulin in Action: Diversity in Target Recognition and Activation Mechanisms

Cell, 2002-03, Vol.108 (6), p.739-742

2002

Volltextzugriff (PDF)

Protein Kinase A Downregulation Delays the Development and Progression of Polycystic Kidney Disease

Journal of the American Society of Nephrology, 2022-06, Vol.33 (6), p.1087-1104

2022

Volltextzugriff (PDF)

MazF Cleaves Cellular mRNAs Specifically at ACA to Block Protein Synthesis in Escherichia coli

Molecular cell, 2003-10, Vol.12 (4), p.913-923

2003

Volltextzugriff (PDF)

Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation

Nature (London), 2000-07, Vol.406 (6791), p.86-90

2000

Volltextzugriff (PDF)

Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window

Journal of medicinal chemistry, 2016-06, Vol.59 (11), p.5520-5541

2016

Volltextzugriff (PDF)

Machine Learning ADME Models in Practice: Four Guidelines from a Successful Lead Optimization Case Study

ACS medicinal chemistry letters, 2024-08, Vol.15 (8), p.1169-1173

2024

Volltextzugriff (PDF)

pHUSH: a single vector system for conditional gene expression

BMC biotechnology, 2007-09, Vol.7 (1), p.61-61, Article 61

2007

Volltextzugriff (PDF)

Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling pathways to the cell cycle

The Journal of biological chemistry, 2017-09, Vol.292 (35), p.14311-14324

2017

Volltextzugriff (PDF)

Structure-Guided Design of Group I Selective p21-Activated Kinase Inhibitors

Journal of medicinal chemistry, 2015-06, Vol.58 (12), p.5121-5136

2015

Volltextzugriff (PDF)

Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors

Journal of medicinal chemistry, 2014-02, Vol.57 (3), p.1033-1045

2014

Volltextzugriff (PDF)

p21-Activated kinase inhibitors: a patent review

Expert opinion on therapeutic patents, 2012-03, Vol.22 (3), p.293-310

2012

Volltextzugriff (PDF)

PAK1 mediates pancreatic cancer cell migration and resistance to MET inhibition

The Journal of pathology, 2014-12, Vol.234 (4), p.502-513

2014

Volltextzugriff (PDF)

Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents

Breast cancer research : BCR, 2015-04, Vol.17 (1), p.59, Article 59

2015

Volltextzugriff (PDF)

Design of Selective PAK1 Inhibitor G‑5555: Improving Properties by Employing an Unorthodox Low‑pK a Polar Moiety

ACS medicinal chemistry letters, 2015-12, Vol.6 (12), p.1241-1246

2015

Volltextzugriff (PDF)

Multiplexed gene expression profiling identifies the FGFR4 pathway as a novel biomarker in intrahepatic cholangiocarcinoma

Oncotarget, 2017-06, Vol.8 (24), p.38592-38601

2017

Volltextzugriff (PDF)

Synthesis and evaluation of a series of 4-azaindole-containing p21-activated kinase-1 inhibitors

Bioorganic & medicinal chemistry letters, 2016-08, Vol.26 (15), p.3518-3524

2016

Volltextzugriff (PDF)

Radixin: cytoskeletal adopter and signaling protein

The international journal of biochemistry & cell biology, 2004-11, Vol.36 (11), p.2131-2136

2004

Volltextzugriff (PDF)

p21-Activated Kinase Inhibitors

The Enzymes, 2013, Vol.34, p.157-180

2013

Volltextzugriff (PDF)

p21-activated kinase 1: PAK'ed with potential

Oncotarget, 2011-06, Vol.2 (6), p.491-496

2011

Volltextzugriff (PDF)

1 – 25 von 55

Suche als RSS-Feed

Aktive Filter

SpracheJapanisch

ThemaMedical Sciences

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(48)
Mit Volltextzugriff
(48)

Publikationsform

Sprache

Englisch
(55)

Erscheinungsjahr

n.n

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 30 Tagen
(1)
... seit 90 Tagen
(2)

Menü

Weitere Dienste

Einstellungen

Targeting cancer with kinase inhibitors

Suppression of HER2/HER3-Mediated Growth of Breast Cancer Cells with Combinations of GDC-0941 PI3K Inhibitor, Trastuzumab, and Pertuzumab

Phosphoproteomic characterization of DNA damage response in melanoma cells following MEK/PI3K dual inhibition

Inhibitors of p21-activated kinases (PAKs)

Active PI3K pathway causes an invasive phenotype which can be reversed or promoted by blocking the pathway at divergent nodes

Evaluation of Protein Kinase cAMP-Activated Catalytic Subunit Alpha as a Therapeutic Target for Fibrolamellar Carcinoma

Calmodulin in Action: Diversity in Target Recognition and Activation Mechanisms

Protein Kinase A Downregulation Delays the Development and Progression of Polycystic Kidney Disease

MazF Cleaves Cellular mRNAs Specifically at ACA to Block Protein Synthesis in Escherichia coli

Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation

Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window

Machine Learning ADME Models in Practice: Four Guidelines from a Successful Lead Optimization Case Study

pHUSH: a single vector system for conditional gene expression

Role of the E3 ubiquitin ligase RNF157 as a novel downstream effector linking PI3K and MAPK signaling pathways to the cell cycle

Structure-Guided Design of Group I Selective p21-Activated Kinase Inhibitors

Back Pocket Flexibility Provides Group II p21-Activated Kinase (PAK) Selectivity for Type I 1/2 Kinase Inhibitors

p21-Activated kinase inhibitors: a patent review

PAK1 mediates pancreatic cancer cell migration and resistance to MET inhibition

Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents

Design of Selective PAK1 Inhibitor G‑5555: Improving Properties by Employing an Unorthodox Low‑pK a Polar Moiety

Multiplexed gene expression profiling identifies the FGFR4 pathway as a novel biomarker in intrahepatic cholangiocarcinoma

Synthesis and evaluation of a series of 4-azaindole-containing p21-activated kinase-1 inhibitors

Radixin: cytoskeletal adopter and signaling protein

p21-Activated Kinase Inhibitors

p21-activated kinase 1: PAK'ed with potential

Aktive Filter

Suchergebnisse filtern