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selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone

Proceedings of the National Academy of Sciences - PNAS, 2010-02, Vol.107 (6), p.2687-2692

2010

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Small-molecule Binding to the DNA Minor Groove Is Mediated by a Conserved Water Cluster

Journal of the American Chemical Society, 2013-01, Vol.135 (4), p.1369-1377

2013

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Pharmacological inhibition of the transcription factor PU.1 in leukemia

The Journal of clinical investigation, 2017-12, Vol.127 (12), p.4297-4313

2017

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A New Generation of Minor-Groove-Binding-Heterocyclic Diamidines That Recognize G·C Base Pairs in an AT Sequence Context

Molecules (Basel, Switzerland), 2019-03, Vol.24 (5), p.946

2019

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Structure of an RNA G-quadruplex from the West Nile virus genome

Nature communications, 2024-06, Vol.15 (1), p.5428-10, Article 5428

2024

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Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines

Nucleic acids research, 2013-01, Vol.41 (1), p.125-138

2013

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Heterocyclic Diamidine DNA Ligands as HOXA9 Transcription Factor Inhibitors: Design, Molecular Evaluation, and Cellular Consequences in a HOXA9-Dependant Leukemia Cell Model

Journal of medicinal chemistry, 2019-02, Vol.62 (3), p.1306-1329

2019

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May the Best Molecule Win: Competition ESI Mass Spectrometry

International Journal of Molecular Sciences, 2015-10, Vol.16 (10), p.24506-24531

2015

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Systematic synthetic and biophysical development of mixed sequence DNA binding agents

Organic & biomolecular chemistry, 2017-01, Vol.15 (4), p.827-835

2017

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Synthesis and antileishmanial evaluation of thiazole orange analogs

Bioorganic & medicinal chemistry letters, 2020-01, Vol.30 (1), p.126725, Article 126725

2020

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Electrostatic control of DNA intersegmental translocation by the ETS transcription factor ETV6

The Journal of biological chemistry, 2017-08, Vol.292 (32), p.13187-13196

2017

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Kinetics and Structures on the Molecular Path to the Quadruplex Form of the Human Telomere

Journal of molecular biology, 2014-04, Vol.426 (8), p.1625-1628

2014

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Structure-specific recognition of quadruplex DNA by organic cations: Influence of shape, substituents and charge

Biophysical chemistry, 2007-03, Vol.126 (1), p.140-153

2007

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Telomestatin and Diseleno Sapphyrin Bind Selectively to Two Different Forms of the Human Telomeric G-Quadruplex Structure

Journal of the American Chemical Society, 2005-07, Vol.127 (26), p.9439-9447

2005

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DNA selection by the master transcription factor PU.1

Cell reports (Cambridge), 2023-07, Vol.42 (7), p.112671-112671, Article 112671

2023

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Differences in isolation rate and antimicrobial susceptibility of bacteria isolated from foals with sepsis at admission and after ≥48 hours of hospitalization

Journal of veterinary internal medicine, 2020-03, Vol.34 (2), p.955-963

2020

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Asymmetrically Substituted Quadruplex-Binding Naphthalene Diimide Showing Potent Activity in Pancreatic Cancer Models

ACS medicinal chemistry letters, 2020-08, Vol.11 (8), p.1634-1644

2020

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Tri- and tetra-substituted naphthalene diimides as potent G-quadruplex ligands

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (5), p.1668-1673

2008

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Unexpected DNA Affinity and Sequence Selectivity through Core Rigidity in Guanidinium-Based Minor Groove Binders

Journal of medicinal chemistry, 2014-09, Vol.57 (18), p.7663-7672

2014

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Thermodynamic Factors That Drive Sequence-Specific DNA Binding of Designed, Synthetic Minor Groove Binding Agents

Life (Basel, Switzerland), 2022-05, Vol.12 (5), p.681

2022

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Kinesic Patterning in Deceptive and Truthful Interactions

Journal of nonverbal behavior, 2015-03, Vol.39 (1), p.1-24

2015

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Prevalence of latent alpha-herpesviruses in Thoroughbred racing horses

The veterinary journal (1997), 2012-08, Vol.193 (2), p.579-582

2012

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Discovery of new G-quadruplex binding chemotypes

Chemical communications (Cambridge, England), 2014-01, Vol.50 (8), p.960-963

2014

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Probing the Electrostatics and Pharmacological Modulation of Sequence-Specific Binding by the DNA-Binding Domain of the ETS Family Transcription Factor PU.1: A Binding Affinity and Kinetics Investigation

Journal of molecular biology, 2013-05, Vol.425 (10), p.1655-1669

2013

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selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone

G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo

Small-molecule Binding to the DNA Minor Groove Is Mediated by a Conserved Water Cluster

Pharmacological inhibition of the transcription factor PU.1 in leukemia

A New Generation of Minor-Groove-Binding-Heterocyclic Diamidines That Recognize G·C Base Pairs in an AT Sequence Context

Structure of an RNA G-quadruplex from the West Nile virus genome

Targeting the DNA-binding activity of the human ERG transcription factor using new heterocyclic dithiophene diamidines

Heterocyclic Diamidine DNA Ligands as HOXA9 Transcription Factor Inhibitors: Design, Molecular Evaluation, and Cellular Consequences in a HOXA9-Dependant Leukemia Cell Model

May the Best Molecule Win: Competition ESI Mass Spectrometry

Systematic synthetic and biophysical development of mixed sequence DNA binding agents

Synthesis and antileishmanial evaluation of thiazole orange analogs

Electrostatic control of DNA intersegmental translocation by the ETS transcription factor ETV6

Kinetics and Structures on the Molecular Path to the Quadruplex Form of the Human Telomere

Structure-specific recognition of quadruplex DNA by organic cations: Influence of shape, substituents and charge

Telomestatin and Diseleno Sapphyrin Bind Selectively to Two Different Forms of the Human Telomeric G-Quadruplex Structure

DNA selection by the master transcription factor PU.1

Differences in isolation rate and antimicrobial susceptibility of bacteria isolated from foals with sepsis at admission and after ≥48 hours of hospitalization

Asymmetrically Substituted Quadruplex-Binding Naphthalene Diimide Showing Potent Activity in Pancreatic Cancer Models

Tri- and tetra-substituted naphthalene diimides as potent G-quadruplex ligands

Unexpected DNA Affinity and Sequence Selectivity through Core Rigidity in Guanidinium-Based Minor Groove Binders

Thermodynamic Factors That Drive Sequence-Specific DNA Binding of Designed, Synthetic Minor Groove Binding Agents

Kinesic Patterning in Deceptive and Truthful Interactions

Prevalence of latent alpha-herpesviruses in Thoroughbred racing horses

Discovery of new G-quadruplex binding chemotypes

Probing the Electrostatics and Pharmacological Modulation of Sequence-Specific Binding by the DNA-Binding Domain of the ETS Family Transcription Factor PU.1: A Binding Affinity and Kinetics Investigation

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