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The Methionine-aromatic Motif Plays a Unique Role in Stabilizing Protein Structure

The Journal of biological chemistry, 2012-10, Vol.287 (42), p.34979-34991

2012

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Oxidation increases the strength of the methionine-aromatic interaction

Nature chemical biology, 2016-10, Vol.12 (10), p.860-866

2016

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Open and Closed Conformations of the Isolated Transmembrane Domain of Death Receptor 5 Support a New Model of Activation

Biophysical journal, 2014-03, Vol.106 (6), p.L21-L24

2014

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Engineered protein-small molecule conjugates empower selective enzyme inhibition

Cell chemical biology, 2022-02, Vol.29 (2), p.328-338.e4

2022

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Piecing it together: Unraveling the elusive structure-function relationship in single-pass membrane receptors

Biochimica et biophysica acta. Biomembranes, 2017-09, Vol.1859 (9), p.1398-1416

2017

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Death Receptor 5 Activation Is Energetically Coupled to Opening of the Transmembrane Domain Dimer

Biophysical journal, 2017-07, Vol.113 (2), p.381-392

2017

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TNFR1 Signaling Is Associated with Backbone Conformational Changes of Receptor Dimers Consistent with Overactivation in the R92Q TRAPS Mutant

Biochemistry (Easton), 2012-08, Vol.51 (33), p.6545-6555

2012

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Modularly assembled porous cell-laden hydrogels

Biomaterials, 2010-06, Vol.31 (18), p.4918-4925

2010

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Death Receptor 5 Networks Require Membrane Cholesterol for Proper Structure and Function

Journal of molecular biology, 2016-12, Vol.428 (24), p.4843-4855

2016

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Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Induces Death Receptor 5 Networks That Are Highly Organized

The Journal of biological chemistry, 2012-06, Vol.287 (25), p.21265-21278

2012

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Physical Hydrogels Photo-Cross-Linked from Self-Assembled Macromers for Potential Use in Tissue Engineering

Biomacromolecules, 2009-12, Vol.10 (12), p.3182-3187

2009

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Minimal Nucleation State of α‑Synuclein Is Stabilized by Dynamic Threonine–Water Networks

ACS chemical neuroscience, 2017-09, Vol.8 (9), p.1859-1864

2017

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An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors

SLAS discovery, 2017-09, Vol.22 (8), p.950-961

2017

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Analysis of Conformational Dynamics Associated with TNFR1 Signaling by Live-Cell FRET and Computational Modeling

Biophysical journal, 2012-01, Vol.102 (3), p.250a-250a

Lewis, Andrew K.

2012

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Investigating the Role of Transmembrane Domain Cysteine Residues in the Organization of TNF Receptors

Biophysical journal, 2016-02, Vol.110 (3), p.227a-227a

2016

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Oxidative Stress Modulates Bioactivity of Lymphotoxin, but not TNF, Through Site-Specific Oxidation of Methionine Residues

Biophysical journal, 2014-01, Vol.106 (2), p.251a-252a

2014

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Computational Studies of Alpha-Synuclein Fibril Formation and Stability

Biophysical journal, 2018-02, Vol.114 (3), p.230a-230a

2018

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TNFR1 Signaling is Associated with Backbone Conformational Changes of Receptor Dimers Consistent with Overactivation in the R92Q TRAPS Mutant

Biophysical journal, 2013-01, Vol.104 (2), p.61a-62a

2013

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Quantitative Analysis of Ligand-Induced Supramolecular Clustering of Death Receptor 5 in Jurkat Cells

Biophysical journal, 2014-01, Vol.106 (2), p.715a-715a

2014

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Methionine-Aromatic Interactions in Calmodulin: A Replica Exchange MD and EPR Spectroscopy Study

Biophysical journal, 2015-01, Vol.108 (2), p.213a-214a

2015

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Signaling in the Tumor Necrosis Factor Superfamily is Driven by Formation of Receptor Networks: Unraveling the Structural and Dynamic Paradigm

Biophysical journal, 2012-01, Vol.102 (3), p.430a-430a

2012

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Oxidation Increases the Strength of the Methionine-Aromatic Interaction

Biophysical journal, 2015-01, Vol.108 (2), p.17a-17a

2015

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Comprehensive Transcriptome Assembly of Chickpea (Cicer arietinum L.) Using Sanger and Next Generation Sequencing Platforms: Development and Applications

PloS one, 2014-01, Vol.9 (1), p.e86039-e86039

2014

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Noninvasive Immunometabolic Cardiac Inflammation Imaging Using Hyperpolarized Magnetic Resonance

Circulation research, 2018-04, Vol.122 (8), p.1084-1093

2018

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Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

PLoS medicine, 2017-01, Vol.14 (1), p.e1002215-e1002215

2017

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The Methionine-aromatic Motif Plays a Unique Role in Stabilizing Protein Structure

Oxidation increases the strength of the methionine-aromatic interaction

Open and Closed Conformations of the Isolated Transmembrane Domain of Death Receptor 5 Support a New Model of Activation

Engineered protein-small molecule conjugates empower selective enzyme inhibition

Piecing it together: Unraveling the elusive structure-function relationship in single-pass membrane receptors

Death Receptor 5 Activation Is Energetically Coupled to Opening of the Transmembrane Domain Dimer

TNFR1 Signaling Is Associated with Backbone Conformational Changes of Receptor Dimers Consistent with Overactivation in the R92Q TRAPS Mutant

Modularly assembled porous cell-laden hydrogels

Death Receptor 5 Networks Require Membrane Cholesterol for Proper Structure and Function

Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Induces Death Receptor 5 Networks That Are Highly Organized

Physical Hydrogels Photo-Cross-Linked from Self-Assembled Macromers for Potential Use in Tissue Engineering

Minimal Nucleation State of α‑Synuclein Is Stabilized by Dynamic Threonine–Water Networks

An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors

Analysis of Conformational Dynamics Associated with TNFR1 Signaling by Live-Cell FRET and Computational Modeling

Investigating the Role of Transmembrane Domain Cysteine Residues in the Organization of TNF Receptors

Oxidative Stress Modulates Bioactivity of Lymphotoxin, but not TNF, Through Site-Specific Oxidation of Methionine Residues

Computational Studies of Alpha-Synuclein Fibril Formation and Stability

TNFR1 Signaling is Associated with Backbone Conformational Changes of Receptor Dimers Consistent with Overactivation in the R92Q TRAPS Mutant

Quantitative Analysis of Ligand-Induced Supramolecular Clustering of Death Receptor 5 in Jurkat Cells

Methionine-Aromatic Interactions in Calmodulin: A Replica Exchange MD and EPR Spectroscopy Study

Signaling in the Tumor Necrosis Factor Superfamily is Driven by Formation of Receptor Networks: Unraveling the Structural and Dynamic Paradigm

Oxidation Increases the Strength of the Methionine-Aromatic Interaction

Comprehensive Transcriptome Assembly of Chickpea (Cicer arietinum L.) Using Sanger and Next Generation Sequencing Platforms: Development and Applications

Noninvasive Immunometabolic Cardiac Inflammation Imaging Using Hyperpolarized Magnetic Resonance

Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach

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