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KcsA-Kv1.x chimeras with complete ligand-binding sites provide improved predictivity for screening selective Kv1.x blockers

The Journal of biological chemistry, 2024-04, Vol.300 (4), p.107155-107155, Article 107155

2024

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Chemical and biophysical characterization of novel potassium channel blocker 3-fluoro-5-methylpyridin-4-amine

Scientific reports, 2024-05, Vol.14 (1), p.11105-11105

2024

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A novel isoquinoline alkaloid HJ-69 isolated from Zanthoxylum bungeanum attenuates inflammatory pain by inhibiting voltage-gated sodium and potassium channels

Journal of ethnopharmacology, 2024-08, Vol.330, p.118218-118218, Article 118218

2024

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Inhibition of voltage-gated potassium channel by aripiprazole in rabbit coronary arterial smooth muscle cells

European journal of pharmacology, 2024-06, Vol.973, p.176610-176610, Article 176610

2024

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Voltage-gated potassium channel 1.3: A promising molecular target in multiple disease therapy

Biomedicine & pharmacotherapy, 2024-06, Vol.175, p.116651-116651, Article 116651

2024

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Synthetic ShK-like Peptide from the Jellyfish Nemopilema nomurai Has Human Voltage-Gated Potassium-Channel-Blocking Activity

Marine drugs, 2024-05, Vol.22 (5), p.217

2024

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The scorpion toxin BeKm‐1 blocks hERG cardiac potassium channels using an indispensable arginine residue

FEBS letters, 2024-04, Vol.598 (8), p.889-901

2024

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Non-vascular ATP-sensitive potassium channel activation does not trigger migraine attacks: A randomized clinical trial

Cephalalgia, 2024-05, Vol.44 (5), p.3331024241248211-3331024241248211

2024

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Purinergic inhibitory regulation of esophageal smooth muscle is mediated by P2Y receptors and ATP-dependent potassium channels in rats

The journal of physiological sciences, 2024-04, Vol.74 (1), p.26-26

2024

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Selective inhibition of A-fiber-mediated excitatory transmission underlies the analgesic effects of KCNQ channel opening in the spinal dorsal horn

Neuropharmacology, 2024-08, Vol.254, p.109994-109994, Article 109994

2024

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An Overview of the Pharmacokinetics and Pharmacodynamics of Landiolol (an Ultra-Short Acting β1 Selective Antagonist) in Atrial Fibrillation

Pharmaceutics, 2024-04, Vol.16 (4), p.517

2024

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Study on peripheral antinociception induced by hydrogen peroxide (H 2 O 2 ): characterization and mechanisms

Naunyn-Schmiedeberg's archives of pharmacology, 2024-05

2024

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Population-specific variations in KCNH2 predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy

Antimicrobial agents and chemotherapy, 2024-03, Vol.68 (5), p.e0139023

2024

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The small conductance Ca 2+ -activated K + channel activator GW542573X impairs hippocampal memory in C57BL/6J mice

Neuropharmacology, 2024-07, Vol.252, p.109960

2024

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The Inhibition of TREK-1 K + Channels via Multiple Compounds Contained in the Six Kamikihito Components, Potentially Stimulating Oxytocin Neuron Pathways

International journal of molecular sciences, 2024-05, Vol.25 (9), p.4907

2024

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Redox Regulation of Mitochondrial Potassium Channels Activity

Antioxidants, 2024-04, Vol.13 (4), p.434

2024

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Synthetic ShK-like Peptide from the Jellyfish INemopilema nomurai/I Has Human Voltage-Gated Potassium-Channel-Blocking Activity

Marine drugs, 2024-05, Vol.22 (5)

2024

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Modelling and analysis of cAMP-induced mixed-mode oscillations in cortical neurons: Critical roles of HCN and M-type potassium channels

PLoS computational biology, 2024-03, Vol.20 (3), p.e1011559-e1011559

2024

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Regulation of T Lymphocyte Functions through Calcium Signaling Modulation by Nootkatone

International journal of molecular sciences, 2024-05, Vol.25 (10), p.5240

2024

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Does the small conductance Ca 2+ -activated K + current I SK flow under physiological conditions in rabbit and human atrial isolated cardiomyocytes?

Journal of molecular and cellular cardiology, 2023-10, Vol.183, p.70

2023

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Vasorelaxant and Blood Pressure-Lowering Effects of Cnidium monnieri Fruit Ethanol Extract in Sprague Dawley and Spontaneously Hypertensive Rats

International journal of molecular sciences, 2024-04, Vol.25 (8), p.4223

2024

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Dilation of Pregnant Rat Uterine Arteries with Phenols from Extra Virgin Olive Oil Is Endothelium-Dependent and Involves Calcium and Potassium Channels

Cells (Basel, Switzerland), 2024-04, Vol.13 (7), p.619

2024

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Polygenic scores for cardiovascular risk factors improve estimation of clinical outcomes in CCB treatment compared to pharmacogenetic variants alone

The pharmacogenomics journal, 2024-06, Vol.24 (3), p.12-12

2024

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Testosterone Enhances K V Currents and Airway Smooth Muscle Relaxation Induced by ATP and UTP through P2Y 4 Receptors and Adenylyl Cyclase Pathway

International journal of molecular sciences, 2024-04, Vol.25 (9)

2024

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KcsA-Kv1.x chimeras with complete ligand-binding sites provide improved predictivity for screening selective Kv1.x blockers

Chemical and biophysical characterization of novel potassium channel blocker 3-fluoro-5-methylpyridin-4-amine

A novel isoquinoline alkaloid HJ-69 isolated from Zanthoxylum bungeanum attenuates inflammatory pain by inhibiting voltage-gated sodium and potassium channels

Inhibition of voltage-gated potassium channel by aripiprazole in rabbit coronary arterial smooth muscle cells

Voltage-gated potassium channel 1.3: A promising molecular target in multiple disease therapy

Synthetic ShK-like Peptide from the Jellyfish Nemopilema nomurai Has Human Voltage-Gated Potassium-Channel-Blocking Activity

In Silico Assisted Identification, Synthesis, and In Vitro Pharmacological Characterization of Potent and Selective Blockers of the Epilepsy-Associated KCNT1 Channel

The scorpion toxin BeKm‐1 blocks hERG cardiac potassium channels using an indispensable arginine residue

Non-vascular ATP-sensitive potassium channel activation does not trigger migraine attacks: A randomized clinical trial

Purinergic inhibitory regulation of esophageal smooth muscle is mediated by P2Y receptors and ATP-dependent potassium channels in rats

Selective inhibition of A-fiber-mediated excitatory transmission underlies the analgesic effects of KCNQ channel opening in the spinal dorsal horn

An Overview of the Pharmacokinetics and Pharmacodynamics of Landiolol (an Ultra-Short Acting β1 Selective Antagonist) in Atrial Fibrillation

Study on peripheral antinociception induced by hydrogen peroxide (H 2 O 2 ): characterization and mechanisms

Population-specific variations in KCNH2 predispose patients to delayed ventricular repolarization upon dihydroartemisinin-piperaquine therapy

The small conductance Ca 2+ -activated K + channel activator GW542573X impairs hippocampal memory in C57BL/6J mice

The Inhibition of TREK-1 K + Channels via Multiple Compounds Contained in the Six Kamikihito Components, Potentially Stimulating Oxytocin Neuron Pathways

Redox Regulation of Mitochondrial Potassium Channels Activity

Synthetic ShK-like Peptide from the Jellyfish INemopilema nomurai/I Has Human Voltage-Gated Potassium-Channel-Blocking Activity

Modelling and analysis of cAMP-induced mixed-mode oscillations in cortical neurons: Critical roles of HCN and M-type potassium channels

Regulation of T Lymphocyte Functions through Calcium Signaling Modulation by Nootkatone

Does the small conductance Ca 2+ -activated K + current I SK flow under physiological conditions in rabbit and human atrial isolated cardiomyocytes?

Vasorelaxant and Blood Pressure-Lowering Effects of Cnidium monnieri Fruit Ethanol Extract in Sprague Dawley and Spontaneously Hypertensive Rats

Dilation of Pregnant Rat Uterine Arteries with Phenols from Extra Virgin Olive Oil Is Endothelium-Dependent and Involves Calcium and Potassium Channels

Polygenic scores for cardiovascular risk factors improve estimation of clinical outcomes in CCB treatment compared to pharmacogenetic variants alone

Testosterone Enhances K V Currents and Airway Smooth Muscle Relaxation Induced by ATP and UTP through P2Y 4 Receptors and Adenylyl Cyclase Pathway

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