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Metabolic support of tumour-infiltrating regulatory T cells by lactic acid

Nature (London), 2021-03, Vol.591 (7851), p.645-651

2021

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Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

Nature immunology, 2021-02, Vol.22 (2), p.205-215

2021

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Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

Nature immunology, 2023-02, Vol.24 (2), p.267-279

2023

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IL-35 mitigates murine acute graft-versus-host disease with retention of graft-versus-leukemia effects

Leukemia, 2015-04, Vol.29 (4), p.939-946

2015

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MicroRNA-17 Modulates Regulatory T Cell Function by Targeting Co-regulators of the Foxp3 Transcription Factor

Immunity (Cambridge, Mass.), 2016-07, Vol.45 (1), p.83-93

2016

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Inducible T-cell receptor expression in precursor T cells for leukemia control

Leukemia, 2015-07, Vol.29 (7), p.1530-1542

2015

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TIM‐1 Signaling Is Required for Maintenance and Induction of Regulatory B Cells

American journal of transplantation, 2015-04, Vol.15 (4), p.942-953

2015

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An IL-27/Lag3 axis enhances Foxp3+ regulatory T cell–suppressive function and therapeutic efficacy

Mucosal immunology, 2016-01, Vol.9 (1), p.137-145

2016

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Unraveling the Therapeutic Benefit of Sequenced Chemo-immunotherapy

Clinical cancer research, 2024-05, Vol.30 (9), p.1705-1707

2024

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Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles

The Journal of experimental medicine, 1993-07, Vol.178 (1), p.27-47

1993

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Simultaneous quantitation of 15 cytokines using a multiplexed flow cytometric assay

Journal of immunological methods, 1999-07, Vol.227 (1), p.41-52

1999

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Utility of Indocyanine Green for Sentinel Lymph Node Biopsy in Pediatric Sarcoma and Melanoma

Journal of pediatric surgery, 2024-07, Vol.59 (7), p.1326-1333

2024

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Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells

Science immunology, 2022-08, Vol.7 (74), p.eabj9123

2022

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Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

Nature (London), 1996-07, Vol.382 (6587), p.171-174

1996

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Preferential control of induced regulatory T cell homeostasis via a Bim/Bcl-2 axis

Cell death & disease, 2012-02, Vol.3 (2), p.e270-e270

2012

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Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted stat6 gene

Nature (London), 1996-04, Vol.380 (6575), p.630-633

1996

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Multiplexed particle-based flow cytometric assays

Journal of immunological methods, 2000-09, Vol.243 (1), p.243-255

Vignali, Dario A.A.

2000

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Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

Nature (London), 1992-08, Vol.358 (6389), p.764-768

1992

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Metabolic Regulation of T Cell Immunity

Immune Metabolism in Health and Tumor, 2017, Vol.1011, p.87-130

2017

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Exhausted T cells in tumors gain suppressor activity and can restrain immunity

Nature immunology, 2023-02, Vol.24 (2), p.218-219

2023

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Regulatory T cells and inhibitory cytokines in autoimmunity

Current opinion in immunology, 2009-12, Vol.21 (6), p.612-618

2009

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On the Dynamics of TCR:CD3 Complex Cell Surface Expression and Downmodulation

Immunity (Cambridge, Mass.), 2000-11, Vol.13 (5), p.665-675

2000

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Amino acid residues that flank core peptide epitopes and the extracellular domains of CD4 modulate differential signaling through the T cell receptor

The Journal of experimental medicine, 1994-06, Vol.179 (6), p.1945-1956

1994

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Processing of an endogenous protein can generate MHC class II-restricted T cell determinants distinct from those derived from exogenous antigen

The Journal of immunology (1950), 1991-11, Vol.147 (10), p.3306-3313

1991

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T Cell Receptor Recognition of MHC Class II–Bound Peptide Flanking Residues Enhances Immunogenicity and Results in Altered TCR V Region Usage

Immunity (Cambridge, Mass.), 1997-09, Vol.7 (3), p.387-399

1997

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Metabolic support of tumour-infiltrating regulatory T cells by lactic acid

Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

Hypoxia drives CD39-dependent suppressor function in exhausted T cells to limit antitumor immunity

IL-35 mitigates murine acute graft-versus-host disease with retention of graft-versus-leukemia effects

MicroRNA-17 Modulates Regulatory T Cell Function by Targeting Co-regulators of the Foxp3 Transcription Factor

Inducible T-cell receptor expression in precursor T cells for leukemia control

TIM‐1 Signaling Is Required for Maintenance and Induction of Regulatory B Cells

An IL-27/Lag3 axis enhances Foxp3+ regulatory T cell–suppressive function and therapeutic efficacy

Unraveling the Therapeutic Benefit of Sequenced Chemo-immunotherapy

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles

Simultaneous quantitation of 15 cytokines using a multiplexed flow cytometric assay

Utility of Indocyanine Green for Sentinel Lymph Node Biopsy in Pediatric Sarcoma and Melanoma

Tumor microenvironmental signals reshape chromatin landscapes to limit the functional potential of exhausted T cells

Requirement for Stat4 in interleukin-12-mediated responses of natural killer and T cells

Preferential control of induced regulatory T cell homeostasis via a Bim/Bcl-2 axis

Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted stat6 gene

Multiplexed particle-based flow cytometric assays

Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in size

Metabolic Regulation of T Cell Immunity

Exhausted T cells in tumors gain suppressor activity and can restrain immunity

Regulatory T cells and inhibitory cytokines in autoimmunity

On the Dynamics of TCR:CD3 Complex Cell Surface Expression and Downmodulation

Amino acid residues that flank core peptide epitopes and the extracellular domains of CD4 modulate differential signaling through the T cell receptor

Processing of an endogenous protein can generate MHC class II-restricted T cell determinants distinct from those derived from exogenous antigen

T Cell Receptor Recognition of MHC Class II–Bound Peptide Flanking Residues Enhances Immunogenicity and Results in Altered TCR V Region Usage

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