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The Role of IGF/IGF-IR-Signaling and Extracellular Matrix Effectors in Bone Sarcoma Pathogenesis

Cancers, 2021-05, Vol.13 (10), p.2478

2021

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Arsenic‐induced IGF‐1 signaling impairment and neurite shortening: The protective roles of IGF‐1 through the PI3K/Akt axis

Environmental toxicology, 2024-03, Vol.39 (3), p.1119-1128

2024

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Therapeutic Targeting of the IGF Axis

Cells (Basel, Switzerland), 2019-08, Vol.8 (8), p.895

2019

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The Insulin/IGF System in Mammalian Sexual Development and Reproduction

International journal of molecular sciences, 2019-09, Vol.20 (18), p.4440

2019

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IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling

eLife, 2018-04, Vol.7

2018

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Disrupting Insulin and IGF Receptor Function in Cancer

International journal of molecular sciences, 2021-01, Vol.22 (2), p.555

2021

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Insulin-like growth factor I receptor blockade enhances chemotherapy and radiation responses and inhibits tumour growth in human gastric cancer xenografts

Gut, 2005-05, Vol.54 (5), p.591-600

2005

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Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I

Diabetes (New York, N.Y.), 2017-01, Vol.66 (1), p.64-74

2017

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The Roles of the IGF Axis in the Regulation of the Metabolism: Interaction and Difference between Insulin Receptor Signaling and IGF-I Receptor Signaling

International journal of molecular sciences, 2021-06, Vol.22 (13), p.6817

2021

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Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II

PloS one, 2011-11, Vol.6 (11), p.e27488

2011

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Microtia patients: Auricular chondrocyte ECM is promoted by CGF through IGF‐1 activation of the IGF‐1R/PI3K/AKT pathway

Journal of cellular physiology, 2019-12, Vol.234 (12), p.21817-21824

2019

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TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations

Nature communications, 2015-08, Vol.6 (1), p.7951-7951, Article 7951

2015

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IGF‐1 regulates astrocytic phagocytosis and inflammation through the p110α isoform of PI3K in a sex‐specific manner

Glia, 2022-06, Vol.70 (6), p.1153-1169

2022

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Tcf7l1 Acts as a Suppressor for the Self‐Renewal of Liver Cancer Stem Cells and Is Regulated by IGF/MEK/ERK Signaling Independent of β‐Catenin

Stem cells (Dayton, Ohio), 2019-11, Vol.37 (11), p.1389-1400

2019

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The combined inhibition of the CaMKIIδ and calcineurin signaling cascade attenuates IGF‐IIR‐induced cardiac hypertrophy

Journal of cellular physiology, 2020-04, Vol.235 (4), p.3539-3547

2020

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IGF-I: A Key Growth Factor that Regulates Neurogenesis and Synaptogenesis from Embryonic to Adult Stages of the Brain

Frontiers in neuroscience, 2016-02, Vol.10, p.52-52

2016

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HSF1 phosphorylation by ERK/GSK3 suppresses RNF126 to sustain IGF‐IIR expression for hypertension‐induced cardiomyocyte hypertrophy

Journal of cellular physiology, 2018-02, Vol.233 (2), p.979-989

2018

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Interaction between IGF-IR and ER induced by E2 and IGF-I

PloS one, 2013-05, Vol.8 (5), p.e62642-e62642

2013

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Transcriptome profiling of Ewing sarcomas – treatment resistance pathways and IGF‐dependency

Molecular oncology, 2020-05, Vol.14 (5), p.1101-1117

2020

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Metformin downregulates the insulin/IGF-I signaling pathway and inhibits different uterine serous carcinoma (USC) cells proliferation and migration in p53-dependent or -independent manners

PloS one, 2013-04, Vol.8 (4), p.e61537

2013

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Activation of the IGF Axis in Thyroid Cancer: Implications for Tumorigenesis and Treatment

International journal of molecular sciences, 2019-07, Vol.20 (13), p.3258

2019

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Igf Signaling is Required for Cardiomyocyte Proliferation during Zebrafish Heart Development and Regeneration

PloS one, 2013-06, Vol.8 (6), p.e67266-e67266

2013

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A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS Fli1-regulated microRNAs

Oncogene, 2011-12, Vol.30 (49), p.4910-4920

2011

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Time‐dependent contribution of BMP, FGF, IGF, and HH signaling to the proliferation of mesenchymal stroma cells during chondrogenesis

Journal of cellular physiology, 2018-11, Vol.233 (11), p.8962-8970

2018

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Human conditions of insulin-like growth factor-I (IGF-I) deficiency

Journal of translational medicine, 2012-11, Vol.10 (1), p.224-224, Article 224

2012

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The Role of IGF/IGF-IR-Signaling and Extracellular Matrix Effectors in Bone Sarcoma Pathogenesis

Arsenic‐induced IGF‐1 signaling impairment and neurite shortening: The protective roles of IGF‐1 through the PI3K/Akt axis

Therapeutic Targeting of the IGF Axis

The Insulin/IGF System in Mammalian Sexual Development and Reproduction

IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling

Disrupting Insulin and IGF Receptor Function in Cancer

Insulin-like growth factor I receptor blockade enhances chemotherapy and radiation responses and inhibits tumour growth in human gastric cancer xenografts

Insulin Regulates Astrocytic Glucose Handling Through Cooperation With IGF-I

The Roles of the IGF Axis in the Regulation of the Metabolism: Interaction and Difference between Insulin Receptor Signaling and IGF-I Receptor Signaling

Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II

Microtia patients: Auricular chondrocyte ECM is promoted by CGF through IGF‐1 activation of the IGF‐1R/PI3K/AKT pathway

TRB3 links insulin/IGF to tumour promotion by interacting with p62 and impeding autophagic/proteasomal degradations

IGF‐1 regulates astrocytic phagocytosis and inflammation through the p110α isoform of PI3K in a sex‐specific manner

Tcf7l1 Acts as a Suppressor for the Self‐Renewal of Liver Cancer Stem Cells and Is Regulated by IGF/MEK/ERK Signaling Independent of β‐Catenin

The combined inhibition of the CaMKIIδ and calcineurin signaling cascade attenuates IGF‐IIR‐induced cardiac hypertrophy

IGF-I: A Key Growth Factor that Regulates Neurogenesis and Synaptogenesis from Embryonic to Adult Stages of the Brain

HSF1 phosphorylation by ERK/GSK3 suppresses RNF126 to sustain IGF‐IIR expression for hypertension‐induced cardiomyocyte hypertrophy

Interaction between IGF-IR and ER induced by E2 and IGF-I

Transcriptome profiling of Ewing sarcomas – treatment resistance pathways and IGF‐dependency

Metformin downregulates the insulin/IGF-I signaling pathway and inhibits different uterine serous carcinoma (USC) cells proliferation and migration in p53-dependent or -independent manners

Activation of the IGF Axis in Thyroid Cancer: Implications for Tumorigenesis and Treatment

Igf Signaling is Required for Cardiomyocyte Proliferation during Zebrafish Heart Development and Regeneration

A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS Fli1-regulated microRNAs

Time‐dependent contribution of BMP, FGF, IGF, and HH signaling to the proliferation of mesenchymal stroma cells during chondrogenesis

Human conditions of insulin-like growth factor-I (IGF-I) deficiency

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