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Role of metabolic H2O2 generation: redox signaling and oxidative stress

The Journal of biological chemistry, 2014-03, Vol.289 (13), p.8735-8741

Sies, Helmut

2014

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Lack of prion transmission barrier in human PrP transgenic Drosophila

The Journal of biological chemistry, 2024-09, Vol.300 (9), p.107617, Article 107617

2024

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Chaperone-mediated autophagy and endosomal microautophagy: Joint by a chaperone

The Journal of biological chemistry, 2018-04, Vol.293 (15), p.5414-5424

2018

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Development of a mouse model expressing a bifunctional glutathione-synthesizing enzyme to study glutathione limitation in vivo

The Journal of biological chemistry, 2024-02, Vol.300 (2), p.105645-105645, Article 105645

2024

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Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues

The Journal of biological chemistry, 2024-07, Vol.300 (7), p.107445, Article 107445

2024

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Oral arsenic administration to humanizedUDP-glucuronosyltransferase1 neonatal mice induces UGT1A1 through a dependence on Nrf2 and PXR

The Journal of biological chemistry, 2023-03, Vol.299 (3), p.102955, Article 102955

2023

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The NSs protein of severe fever with thrombocytopenia syndrome virus differentially inhibits the type 1 interferon response among animal species

The Journal of biological chemistry, 2023-06, Vol.299 (6), p.104819-104819, Article 104819

2023

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Abstract 2164 Familial Thrombocytopenia-Associated Germline ETV6 P214L Mutation Results in XPO1-Mediated Nuclear Export

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.106030, Article 106030

2024

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Investigating the mechanism of photoisomerization in jellyfish rhodopsin with the counterion at an atypical position

The Journal of biological chemistry, 2023-06, Vol.299 (6), p.104726-104726, Article 104726

2023

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Combined Liver X Receptor/Peroxisome Proliferator-activated Receptor γ Agonist Treatment Reduces Amyloid β Levels and Improves Behavior in Amyloid Precursor Protein/Presenilin 1 Mice

The Journal of biological chemistry, 2015-08, Vol.290 (35), p.21591-21602

2015

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Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the Alzheimer disease mouse model: in vivo and in vitro studies

The Journal of biological chemistry, 2013-01, Vol.288 (2), p.1295-1306

2013

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Gut microbial β-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens

The Journal of biological chemistry, 2019-12, Vol.294 (49), p.18586-18599

2019

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Hypokinesia and Reduced Dopamine Levels in Zebrafish Lacking β- and γ1-Synucleins

The Journal of biological chemistry, 2012-01, Vol.287 (5), p.2971-2983

2012

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Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1–40 deposition underlies plaque polymorphism in progressing Alzheimer’s disease pathology

The Journal of biological chemistry, 2019-04, Vol.294 (17), p.6719-6732

2019

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Vitamin D receptor targets hepatocyte nuclear factor 4α and mediates protective effects of vitamin D in nonalcoholic fatty liver disease

The Journal of biological chemistry, 2020-03, Vol.295 (12), p.3891-3905

2020

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Triclosan administration to humanized UDP-glucuronosyltransferase 1 neonatal mice induces UGT1A1 through a dependence on PPARα and ATF4

The Journal of biological chemistry, 2024-06, Vol.300 (6), p.107340, Article 107340

2024

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The emerging role of α-synuclein truncation in aggregation and disease

The Journal of biological chemistry, 2020-07, Vol.295 (30), p.10224-10244

2020

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Iso-α-acids, Bitter Components of Beer, Prevent Inflammation and Cognitive Decline Induced in a Mouse Model of Alzheimer's Disease

The Journal of biological chemistry, 2017-03, Vol.292 (9), p.3720-3728

2017

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Three dimensional and four dimensional live imaging to study mechanisms of progressive neurodegeneration

The Journal of biological chemistry, 2024-07, Vol.300 (7), p.107433, Article 107433

2024

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Are N- and C-terminally truncated Aβ species key pathological triggers in Alzheimer's disease?

The Journal of biological chemistry, 2018-10, Vol.293 (40), p.15419-15428

2018

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eIF5 stimulates the CUG initiation of RAN translation of poly-GA dipeptide repeat protein (DPR) in C9orf72 FTLD/ALS

The Journal of biological chemistry, 2024-03, Vol.300 (3), p.105703-105703, Article 105703

2024

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Impaired malin expression and interaction with partner proteins in Lafora disease

The Journal of biological chemistry, 2024-05, Vol.300 (5), p.107271, Article 107271

2024

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Widespread and Enzyme-independent Nϵ-Acetylation and Nϵ-Succinylation of Proteins in the Chemical Conditions of the Mitochondrial Matrix

The Journal of biological chemistry, 2013-10, Vol.288 (40), p.29036-29045

2013

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Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity

The Journal of biological chemistry, 2020-12, Vol.295 (52), p.17986-17996

2020

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Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase

The Journal of biological chemistry, 2015-06, Vol.290 (26), p.16043-16058

2015

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Role of metabolic H2O2 generation: redox signaling and oxidative stress

Lack of prion transmission barrier in human PrP transgenic Drosophila

Chaperone-mediated autophagy and endosomal microautophagy: Joint by a chaperone

Development of a mouse model expressing a bifunctional glutathione-synthesizing enzyme to study glutathione limitation in vivo

Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues

Oral arsenic administration to humanizedUDP-glucuronosyltransferase1 neonatal mice induces UGT1A1 through a dependence on Nrf2 and PXR

The NSs protein of severe fever with thrombocytopenia syndrome virus differentially inhibits the type 1 interferon response among animal species

Abstract 2164 Familial Thrombocytopenia-Associated Germline ETV6 P214L Mutation Results in XPO1-Mediated Nuclear Export

Investigating the mechanism of photoisomerization in jellyfish rhodopsin with the counterion at an atypical position

Combined Liver X Receptor/Peroxisome Proliferator-activated Receptor γ Agonist Treatment Reduces Amyloid β Levels and Improves Behavior in Amyloid Precursor Protein/Presenilin 1 Mice

Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the Alzheimer disease mouse model: in vivo and in vitro studies

Gut microbial β-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens

Hypokinesia and Reduced Dopamine Levels in Zebrafish Lacking β- and γ1-Synucleins

Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1–40 deposition underlies plaque polymorphism in progressing Alzheimer’s disease pathology

Vitamin D receptor targets hepatocyte nuclear factor 4α and mediates protective effects of vitamin D in nonalcoholic fatty liver disease

Triclosan administration to humanized UDP-glucuronosyltransferase 1 neonatal mice induces UGT1A1 through a dependence on PPARα and ATF4

The emerging role of α-synuclein truncation in aggregation and disease

Iso-α-acids, Bitter Components of Beer, Prevent Inflammation and Cognitive Decline Induced in a Mouse Model of Alzheimer's Disease

Three dimensional and four dimensional live imaging to study mechanisms of progressive neurodegeneration

Are N- and C-terminally truncated Aβ species key pathological triggers in Alzheimer's disease?

eIF5 stimulates the CUG initiation of RAN translation of poly-GA dipeptide repeat protein (DPR) in C9orf72 FTLD/ALS

Impaired malin expression and interaction with partner proteins in Lafora disease

Widespread and Enzyme-independent Nϵ-Acetylation and Nϵ-Succinylation of Proteins in the Chemical Conditions of the Mitochondrial Matrix

Coronavirus infection and PARP expression dysregulate the NAD metabolome: An actionable component of innate immunity

Ganglioside GD3 Enhances Invasiveness of Gliomas by Forming a Complex with Platelet-derived Growth Factor Receptor α and Yes Kinase

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