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High-content phenotypic and pathway profiling to advance drug discovery in diseases of unmet need

Cell chemical biology, 2021-03, Vol.28 (3), p.338-355

2021

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Chemogenomic library design strategies for precision oncology, applied to phenotypic profiling of glioblastoma patient cells

iScience, 2023-07, Vol.26 (7), p.107209, Article 107209

2023

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Clinical features associated with trait-impulsiveness in euthymic bipolar disorder patients

Journal of affective disorders, 2013-01, Vol.144 (3), p.240-247

2013

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Recombinant cell bioassays for the detection of (gluco)corticosteroids and endocrine-disrupting potencies of several environmental PCB contaminants

Analytical and bioanalytical chemistry, 2011-08, Vol.401 (3), p.873-882

2011

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Development of a rapid yeast estrogen bioassay, based on the expression of green fluorescent protein

Gene, 2004-01, Vol.325, p.187-200

2004

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Validation of a recombinant cell bioassay for the detection of (gluco)corticosteroids in feed

Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 2013-02, Vol.30 (2), p.264-271

2013

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Discovery of senolytics using machine learning

Nature communications, 2023-06, Vol.14 (1), p.3445-3445, Article 3445

2023

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A cautionary note on the use of N-acetylcysteine as a reactive oxygen species antagonist to assess copper mediated cell death

PloS one, 2023-12, Vol.18 (12), p.e0294297-e0294297

2023

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EcoFlex: A Multifunctional MoClo Kit for E. coli Synthetic Biology

ACS synthetic biology, 2016-10, Vol.5 (10), p.1059-1069

2016

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Stereoselective synthesis of deoxy analogues of the 3C-protease inhibitor thysanone

Tetrahedron, 2002, Vol.58 (1), p.183-189

2002

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Discovery of pyrazolopyrimidines that selectively inhibit CSF-1R kinase by iterative design, synthesis and screening against glioblastoma cells

RSC medicinal chemistry, 2023-12, Vol.14 (12), p.2611-2624

2023

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Biological Materials: The Next Frontier for Cell-Free Synthetic Biology

Frontiers in bioengineering and biotechnology, 2020-05, Vol.8, p.399-399

2020

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Specific Nucleic AcId Ligation for the detection of Schistosomes: SNAILS

PLoS neglected tropical diseases, 2022-07, Vol.16 (7), p.e0010632-e0010632

2022

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A study of the real-world effectiveness of group psychoeducation for bipolar disorders: Is change in illness perception a key mediator of benefit?

Journal of affective disorders, 2018-02, Vol.227, p.713-720

2018

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The cylindromatosis gene product, CYLD, interacts with MIB2 to regulate notch signalling

Oncotarget, 2014-12, Vol.5 (23), p.12126-12140

2014

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Addition of silyloxydienes to 2-substituted 1,4-benzoquinones and 1,4-naphthoquinones

Tetrahedron, 1997-06, Vol.53 (22), p.7715-7730

1997

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High-Content Phenotypic Profiling in Esophageal Adenocarcinoma Identifies Selectively Active Pharmacological Classes of Drugs for Repurposing and Chemical Starting Points for Novel Drug Discovery

SLAS discovery, 2020-08, Vol.25 (7), p.770-782

2020

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Gloom and doom? The future of marine capture fisheries

Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2005-01, Vol.360 (1453), p.21-46

2005

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β2-microglobulin: a biomarker for bipolar disorder and schizophrenia?

European neuropsychopharmacology, 2017-10, Vol.27, p.S635-S636

2017

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P.1.f.023 - β2-microglobulin: a biomarker for bipolar disorder and schizophrenia?

European neuropsychopharmacology, 2017-10, Vol.27, p.S635-S636

2017

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Application of a High-Content Screening Assay Utilizing Primary Human Lung Fibroblasts to Identify Antifibrotic Drugs for Rapid Repurposing in COVID-19 Patients

SLAS discovery, 2021-10, Vol.26 (9), p.1091-1106

2021

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Morphological profiling in human neural progenitor cells classifies hits in a pilot drug screen for Alzheimer's disease

Brain communications, 2024, Vol.6 (2), p.fcae101-fcae101

2024

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The status of routine fishery data collection in Southeast Asia, central America, the South Pacific, and West Africa, with special reference to small-scale fisheries

ICES journal of marine science, 2011-09, Vol.68 (8), p.1743-1750

2011

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Rapid yeast estrogen bioassays stably expressing human estrogen receptors α and β, and green fluorescent protein: a comparison of different compounds with both receptor types

The Journal of steroid biochemistry and molecular biology, 2004-07, Vol.91 (3), p.99-109

2004

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new highly specific and robust yeast androgen bioassay for the detection of agonists and antagonists

Analytical and bioanalytical chemistry, 2007-11, Vol.389 (5), p.1549-1558

2007

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High-content phenotypic and pathway profiling to advance drug discovery in diseases of unmet need

Chemogenomic library design strategies for precision oncology, applied to phenotypic profiling of glioblastoma patient cells

Clinical features associated with trait-impulsiveness in euthymic bipolar disorder patients

Recombinant cell bioassays for the detection of (gluco)corticosteroids and endocrine-disrupting potencies of several environmental PCB contaminants

Development of a rapid yeast estrogen bioassay, based on the expression of green fluorescent protein

Validation of a recombinant cell bioassay for the detection of (gluco)corticosteroids in feed

Discovery of senolytics using machine learning

A cautionary note on the use of N-acetylcysteine as a reactive oxygen species antagonist to assess copper mediated cell death

EcoFlex: A Multifunctional MoClo Kit for E. coli Synthetic Biology

Stereoselective synthesis of deoxy analogues of the 3C-protease inhibitor thysanone

Discovery of pyrazolopyrimidines that selectively inhibit CSF-1R kinase by iterative design, synthesis and screening against glioblastoma cells

Biological Materials: The Next Frontier for Cell-Free Synthetic Biology

Specific Nucleic AcId Ligation for the detection of Schistosomes: SNAILS

A study of the real-world effectiveness of group psychoeducation for bipolar disorders: Is change in illness perception a key mediator of benefit?

The cylindromatosis gene product, CYLD, interacts with MIB2 to regulate notch signalling

Addition of silyloxydienes to 2-substituted 1,4-benzoquinones and 1,4-naphthoquinones

High-Content Phenotypic Profiling in Esophageal Adenocarcinoma Identifies Selectively Active Pharmacological Classes of Drugs for Repurposing and Chemical Starting Points for Novel Drug Discovery

Gloom and doom? The future of marine capture fisheries

β2-microglobulin: a biomarker for bipolar disorder and schizophrenia?

P.1.f.023 - β2-microglobulin: a biomarker for bipolar disorder and schizophrenia?

Application of a High-Content Screening Assay Utilizing Primary Human Lung Fibroblasts to Identify Antifibrotic Drugs for Rapid Repurposing in COVID-19 Patients

Morphological profiling in human neural progenitor cells classifies hits in a pilot drug screen for Alzheimer's disease

The status of routine fishery data collection in Southeast Asia, central America, the South Pacific, and West Africa, with special reference to small-scale fisheries

Rapid yeast estrogen bioassays stably expressing human estrogen receptors α and β, and green fluorescent protein: a comparison of different compounds with both receptor types

new highly specific and robust yeast androgen bioassay for the detection of agonists and antagonists

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